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Biomedical subjects

M Palumbo

Publications and source records attributed to M Palumbo.

166 records · Page 10Linked to original sources

[Formation of various types of complexes upon the interaction of anthraquinones with DNA].

The optical properties (circular and linear dichroism) of the 11 anthraquinone antibiotics complexed with DNA molecules under conditions giving rise to cholesteric liquid-crystalline dispersions were investigated. Complexes of compounds A911 and A912 with double-stranded linear or circular DNA molecules differ strongly in their properties from those of other anthraquinones. The possible reasons of these differences and their possible correlation with the biological activity of the A911 and A912 are discussed.

Animals↗

Quality of life in shift work syndrome.

Air Force radar controllers represent an excellent example of night shift workers, as they are obliged to demonstrate perfect alertness during working hours. We set out: a) to assess the quality of life in these shift workers; b) to identify those with shift work syndrome and c) to evaluate the possible effects of triazolam both on their quality of life and sleep. The results reveal an impairment of the quality of life in shift workers, independently of the presence of a circadian rhythm sleep disorder. Quality of life was more severely impaired in subjects with circadian rhythm sleep disorder. Hypnotic therapy brought about an improvement both in the sleep disorder and in the quality of life of subjects affected by shift work syndrome. Selective alertness tests failed to demonstrate any "sedative carry-over" in the treated patients.

Adult↗