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Biomedical subjects

M Pakkanen

Publications and source records attributed to M Pakkanen.

8 recordsLinked to original sources
PubMed1996

Biodegradable positive fixation for the endoscopic brow lift.

Development of endoscopic techniques allows the separation and repositioning of the periosteum of the orbital rims and zygomaxilla for a brow lift without skin excision. Questions have been raised about the permanence of this repositioning without fixation. We have developed a technique using biodegradable polylactide pericranial pins that serve as fixation points to allow specific suspension of the periosteum with positive positioning until the third phase of wound healing is complete. Through two inconspicuous incisions near the midportion of the scalp, subperiosteal dissection is carried to the orbital rims and the zygomatic arch anteriorly and all the way to the base of the occiput posteriorly. This allows for contracture of the occipitalis muscle to contribute to the repositioning and lifting of the brow. Up to seven sutures are then placed through and through the pericranium of the periosteum and frontalis along the superior and lateral border of the orbital rim. These stitches of long-acting polylactide acid are secured to two pins placed in the outer table of the cranium to maintain positive fixation for more than 6 weeks. In this way precise, positive positioning is maintained until wound healing and reattachment of the structures are complete. We began these procedures in 1993; our results at 24 months are promising.

Endoscopy↗
PubMed1977

Survival rates of patients with malignant melanoma of the skin.

This paper reports on cases of malignant melanoma of the skin diagnosed in Finland between 1963 and 1968. Sufficient data for estimating the survival was obtained in 691 cases. The ten-year relative survival rate for the entire series was 41% for males and 53% for females. This sex difference remained constant throughout the various divisions of the material. The ten-year relative survival rate of males with tumour in stage I was 52% and that of females 59%. The highest survival rate of stage I tumour in males was for the tumours of the lower extremities (77%) and in females for those in the head and neck (79%). The relative survival of patients with tumour of the trunk in stage I was lowest in both sexes (males 49%, females 45%). The ten-year relative survival rate of patients with a local recurrence was 33% in males and 27% in females. The relative ten-year survival rates of patients with superficial melanoma were 130% in males and 92% in females.

Female↗
PubMed1977

Clinical appearance and treatment of malignant melanoma of the skin.

A report is presented on cases of malignant melanoma of the skin recorded in the Finnish Cancer Registry between 1963 and 1968. The material consisted of 693 cases where the diagnosis of melanoma was confirmed by reclassification of the histological specimens and/or by careful perusal of the hospital records. In females melanoma was most frequent on the lower extremities (43%). One half of the tumours of males were located on the trunk and two thirds of these where on the posterior side of the trunk. Most of the tumours were in stage I at the time of diagnosis (males 75%, females 80%). The mean duration of symptoms, was 4.0 months in males and 4.2 months in females. In stage I, the duration of symptoms was under four months in 40% of cases and in stage II in 37% of cases, whereas in stage III this figure was 68%. The most common symptoms were increase in size (46%) and bleeding from the tumour (11%). Only 28 patients were treated radically while "wide" excision was the most common surgical method (48%).

Adolescent↗