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Biomedical subjects

M P Rubinstein

Publications and source records attributed to M P Rubinstein.

21 records · Page 2Linked to original sources

The visually evoked subcortical potential: is related to the electroretinogram?

The visually evoked subcortical potential (VESP) of mean latencies P21-N28-P36 has previously been recorded at an electrode site around the mastoid process. An initial topographical study of the potential indicated that it was independent of the electroretinogram (ERG), and monocular stimulation showed bilateral reduction, which suggests that the VESP is of postchiasmal origin. A more detailed topographical study of the scalp and facial distribution of the ERG and its oscillatory potentials has been carried out, with simultaneous recording of the VESP. Two monocular fields of ERG activity have been demonstrated, each having a wide area of distribution and interacting medially. Remnants of the ERG b-wave have been detected at many electrode sites, but they were of different amplitude and morphology from the VESP. Results are also presented from two atypical control subjects and two patients, providing further evidence of the separate genesis of the ERG and VESP.

Adult↗

The scalp topography of the human visually evoked subcortical potential.

Stimulus and analysis parameters have been adjusted to provide optimum conditions for producing and recording the early components of flash visual evoked potentials. A visual evoked subcortical potential (VESP) of mean latency P23-N28-P34 has been recorded in 86% of subjects. The triphasic wave was maximal at an electrode position slightly posterior to the Rolandic/sylvian fissure and topographically separate from the lid electroretinogram and the visual evoked cortical potential. Monocular stimulation shows bilateral reduction of the amplitude of the VESP, indicating that the wave is independent of the retina and optic nerve and must be arising from a postchiasmal site.

Adult↗

The optics of fundus examination.

It has been 140 years since the invention of the ophthalmoscope in 1851 by Herman von Helmholtz. Since then, a considerable amount of time and effort has been devoted to improving the clinician's view of the fundus both for diagnostic and therapeutic reasons. Recently, there have been some notable advances in this respect, such as the 90 diopter lens, the "2.2 pan retinal" lens, and numerous "wide angle" fundus-viewing contact lenses to which the Volk Quadraspheric fundus lens has been the most recent addition. This paper is a review of the optical principles underlying the methods of fundus examination currently available.

Fundus Oculi↗