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Biomedical subjects

M P Frick

Publications and source records attributed to M P Frick.

At least 73 records · Page 4Linked to original sources
PubMed1981

Ultrasound in acute renal transplant rejection.

Gray-scale ultrasound and biopsy were compared in 63 patients with suspected acute kidney allograft rejection. Sonographic findings of increased size and decreased echogenicity of renal pyramide, focal zones of sonolucency in renal cortex, and patchy sonolucent areas involving both cortex and medulla with coalescence correlated well with biopsy in 46 out of 50 patients (92%) treated for acute rejection (sensitivity = 0.92). Abnormal perirenal fluid collection was encountered in three out of 60 patients (5%). Out of 63 sonographic studies, 10 (16%) gave either false positive (6) or false negative (4) results for an overall accuracy of 85%.

Biopsy↗
PubMed1980

The scintigraphic appearance of the spleen following splenic artery resection.

Sequential 99mTc-sulfur colloid scans were performed on 4 patients following resection of the splenic artery and vein during donor pancreatectomy. Immediate postoperative scans showed markedly decreased or absent uptake. Over a period of two weeks the appearance returned to normal in 3 and peripheral defects were seen in 1. A patient studied after splenic artery ligation for trauma also demonstrated prompt recovery. These studies show that the normal spleen can tolerate ligation of the splenic artery and vein.

Colloids↗
PubMed1980

Uro- and angiographic findings in a "normal" population: screening of 151 symptom-free potential transplant donors for renal disease.

Potentially significant renal abnormalities were encountered in 7.3% of 151 symptom-free renal transplant donors and included renal cysts, cortical adenoma, ectopic and solitary kidney, and vascular abnormalities. Findings as they relat to donation of a kidney were important in 2.1% of patients and included solitary kidney and certain rare vascular variants rejected for technical reasons and danger of distal ureteral necrosis after transplantation.

Adolescent↗
PubMed1979

Indium 111 autologous tagged leukocytes in the diagnosis of intraperitoneal sepsis.

We report the results of a new test, indium oxine in 111 scanning, in the diagnosis of postoperative infection. Indium 111 was used to label autologous polymorphonuclear leukocytes, which when reinjected migrate to sites of infection, inflammation, or both. Standard scintigraphy localizes the labeled inflammatory cells at these sites. Sixty-six scans were performed in 43 surgical patients. Thirty-seven scans were categorized as true-positive; 19 scans were categorized as true-negative. Therefore, the accuracy rate was 85%. Two scans (3%) in one patient represented false-positive results. Two scans (3%) were positive for inflammation but there was no infection present; this group was denoted as equivocal. Six scans (9%) were false-negative; false-negative scans are more likely in old lesions with poor blood supply and in areas that overlap regions of normal uptake. The noninvasive nature of the test, high accuracy rate, and ease of administration make it a potentially useful tool in the diagnosis of postoperative infection.

Abscess↗
PubMed1979

Computer tomography, radionuclide imaging and ultrasonography in hepatic mass lesions.

The livers of 86 patients comprising this report were examined by both transmission computerized tomography (CT) and radionuclide scans (LS). Fifty-nine of them were also examined by gray-scale ultrasound (US). In a comparative study, the strengths and weaknesses of each modality were evaluated. CT demonstrated 85%. US 82%, and LS 73% of masses involving the liver. Because of better resolution and sectioning capabilities, together with stop-motion imaging, CT and US detected smaller and deeper mass lesions than did LS. However, LS was more informative in hepatocellular disorders than was US or CT. Our experience indicated that information obtained on the liver and surrounding structures by each imaging modality used here tends to be somewhat unique, and thus these procedures complement one another rather than being competitive.

Humans↗
PubMed1979

Evaluation of retroperitoneum with computerized tomography and ultrasonography in patients with testicular tumors.

Results of CT and US examinations in 24 patients with testicular tumors yielded similar sensitivity and specificity in the diagnosis of enlarged retroperitoneal lymph nodes found at laparatomy. Therefore, the choice of either imaging modality may be influenced by other factors such as presence of abundant bowel gas, post-operative wounds, surgical clips in the abdomen, cachexia or obesity.

Adult↗
PubMed1979

Evaluation of three imaging instruments in dogs with liver hemotomas: concise communication.

Single-gamma emission computerized tomography (ECT) was compared with transmission computerized tomography (TCT) and scintillation-camera imaging (SC) in eight dogs with acute, solitary hematomas in the left liver lobe. The superior performance of TCT was attributed to its inherently better spatial resolution than those of ECT or SC, and to the fact that studies with TCT could be performed during apnea. ECT was more sensitive than SC to small changes in the spatial distribution of radionuclides. In addition, the ECT, by virtue of its sectioning capability, was more sensitive than is SC to differences in radionuclide concentrations at same depth in an organ.

Animals↗
PubMed1978

Scintigraphic visualization of myocardial infarcts in baboons using thallium-201 and technetium-99m pyrophosphate.

4 baboons with myocardial infarcts were evaluated using thallium-201 for myocardial imaging and 99Tcm pyrophosphate for infarct visualization. Scintiphotographic findings were compared with the size of myocardial infarcts calculated from measurements of the activity of MB isoenzymes of creatine kinase (CK-MB) in serum and in the myocardium at autopsy, as described by Sobel's method. Lack of thallium-201 accumulation was noted in left ventricular infarcts of 3 of the 4 baboons. These same areas localized 99Tcm pyrophosphate administered 24--30 h after infarction.

Animals↗
PubMed1976

Use of 99mTc-sulfur colloid in evaluation of renal transplant complications.

Technetium-99m-sulfur colloid (TSC) was administered to 45 renal transplant patients. No TSC accumulation was seen in normally functioning transplant kidneys. Accumulation of TSC was found in 89% of transplants with rejection, in 30% of transplants exhibiting acute tubular necrosis, and in 30% of transplants of patients with sepsis. Renal accumulation of TSC in various transplant complications diminishes the value of this technique for monitoring transplant rejection.

Acute Kidney Injury↗
PubMedDate not supplied

Evaluation of abdominal fistulas with computed body tomography (CT).

Twenty-nine patients with 32 abdominal fistulas were evaluated by sinograms and CT. Sinograms were superior to CT in displaying the fistulous tract and its communications to specific organ systems. Ct added information affecting treatment plan or surgical approach by defining extent, nature and location of underlying disease, by eliminating overlap opacified fistulas, cavities, bowel loops and surface contaminations and by detecting additional undrained abscesses or recurrent tumor masses. While sinograms remain the initial procedure in the evaluation of abdomina fistulas, CT offers a useful secondary modality in selected instances.

Abdominal Muscles↗