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Biomedical subjects

M P France

Publications and source records attributed to M P France.

15 recordsLinked to original sources

Optimizing arthroscopic knots.

Arthroscopic repairs, such as those for shoulder instability, are commonly performed. However, the failure rate after arthroscopic repair appears to be higher than with open surgery. These failures may relate to the challenge of tying secure knots arthroscopically. Many knots tied arthroscopically commonly consist of an initial slip knot to remove slack, and a series of half-hitches. Half-hitches, instead of square throws, are difficult to avoid and result when asymmetrical tension is applied to the strands. For this reason, the security of knots tied arthroscopically may not be equivalent to square knots and a greater rate of failure may occur. The purpose of this study was to determine (1) the security of various arthroscopic knots under cyclic and peak loading conditions, (2) how the surgeon can modify the method or sequence of half-hitch throws to minimize knot slippage or breakage, and (3) whether using an arthroscopic knot pusher affects the security of the same knot tied by hand. The most secure knot configurations were achieved by reversing the half-hitch throws and alternating the posts. These knots performed significantly better than all other knots tested (P < .002). Thus the surgeon can control the holding capacity and minimize suture loop displacement by proper alternation of the tying strands and reversal of the loop when placing the hitches.(ABSTRACT TRUNCATED AT 250 WORDS)

Arthroscopy

Basophil leucocytes in responses to parasitic infection and some other stimuli in sheep.

Basophil leucocytes are a significant component of the infiltrating cells in a variety of tissue reactions in guinea pigs. However, little is known about the participation of basophils in similar reactions in most other animal species. The circulating blood, skin and small intestinal mucosa of sheep were examined after they had received stimuli known to elicit basophil-rich responses in guinea pigs but relatively few basophils were found.

Animals

Chronic intestinal pseudo-obstruction in a dog.

A three-year-old neutered female Border Collie was presented with inappetence, vomiting and diarrhoea. Abdominal radiographs revealed an obstructive pattern but no physical obstruction was evident at laparotomy. A diagnosis of chronic intestinal pseudo-obstruction was made based on histopathological changes in intestinal biopsies. Treatment was unsuccessful and the dog deteriorated progressively until euthanased five weeks after presentation.

Animals

Disassembly of a modular humeral prosthesis. A case report.

A modular humeral hemiarthroplasty utilizing a prosthesis with a taper-lock design was performed on a 77-year-old woman with a diagnosis of rotator cuff arthropathy. Radiographic examination at 3 months after surgery revealed disarticulation of the modular head and neck from the humeral prosthetic stem. This is a case report of a disarticulated modular humeral hemiarthroplasty.

Aged

Pudendal nerve palsy following fracture table traction.

In separate retrospective and prospective studies at the same Level 1 trauma center, pudendal nerve palsy complicating fracture table cases was analyzed. Incidence was established and pertinent variables categorized and compared. From January 1986 through October 1988, four of 216 fracture table patients (1.9%) were diagnosed with a postoperative pudendal nerve palsy. A subsequent three-month prospective study, ensuring use of preventive measures and incorporating active postoperative screening, resulted in only one of 36 patients (2.8%) developing this complication after fracture table traction. Symptoms associated with this palsy, including genitoperineal hypoesthesia, erectile dysfunction, or both, occurred within the first two postoperative days and resolved spontaneously by six months. No association of variables had any statistical significance. The pathoanatomy of this complication and preventive guidelines are reviewed.

Adolescent

Painful internal disc derangements of the lumbosacral spine: discographic diagnosis and treatment by posterior lumbar interbody fusion.

Results of surgical or non-surgical treatment of patients with chronic persistent low back pain, but without clearly demonstrable diagnosis of disc herniation, spinal stenosis, or spinal instability, range between 50% to 80% of success rates in the literature. Between 1984 and 1988, the authors reviewed 25 consecutive cases of internal derangements of the lumbar disc treated by subtotal disc excision and interbody fusion. All patients had chronic, persistent, or frequently recurring low back pain resistant to active nonoperative treatments for a minimum of 3 months (mean: 16); no evidence of disc herniation, stenosis, or instability; no previous operation; single level of the pathologic condition in L-S spine; and diagnosis made by clinical information, CT, MRI, and/or discography. Ages ranged from 25 to 51 (mean: 38 to 40). Average follow up was 2 years (range: 13 to 57 months). In addition, 20 patients (32 discographics) who had available information of discography, MRI, and CT scan of the L-S spine, were reviewed for the relationship between disc morphology, pressure, volume, and pain response during discography. Overall clinical results for the 25 patients were: 58% excellent (15 of 26), 31% good (8 of 26), and 11% fair (3 of 26). No patients were in the "poor" category. The successful fusion rate was 95%.

Back Pain

Nonhemophilic hemosiderotic synovitis of the shoulder. A case report.

In a nonhemophilic 72-year-old man, a persistent degenerative hemarthrosis of the shoulder joint was associated with a complete tear of the rotator cuff. Extensive, rusty synovial pigmentation and hyperplasia (hemosiderotic synovitis) mimicking pigmented villonodular synovitis (PVS) were noted at surgery. Spontaneous hemarthrosis of the shoulder includes rapid onset of severe pain, limitation of movement, subsequent appearance of a bruise on the affected shoulder and arm, and radiological evidence of joint degeneration. Hemosiderotic synovitis results from chronic intraarticular bleeding. With the breakdown of trapped hemoglobin, iron-containing hemosiderin is stored in synovial tissue producing rusty discoloration and proliferative reaction. The classic cytoarchitecture of PVS has additional subsynovial nodular proliferation of mononuclear cells. Hemarthrosis may produce significant structural alteration of joints. Its prompt recognition and the awareness of underlying causes should lead to earlier diagnosis, appropriate therapy, less joint destruction, and better outcomes.

Aged

Perioperative blood loss associated with total knee arthroplasty. A comparison of procedures performed with and without cementing.

We reviewed the cases of thirty-four patients (thirty-eight knees) in whom prostheses with an identical design were used for primary total knee arthroplasty, and we compared the perioperative blood loss between the eleven knees in which cement was used and the twenty-seven knees in which cement was not used. The patients who had an uncemented prosthesis had a significantly greater mean blood loss, both intraoperatively (p less than or equal to 0.05) and during each subsequent eight-hour interval on the first postoperative day (p less than or equal to 0.05). The total for the forty-eight-hour postoperative collection also was greater (p less than or equal to 0.01), as was the cumulative loss for the entire study (p less than or equal to 0.01). When patients who had rheumatoid arthritis and osteoarthrosis were considered separately, the results were similar; that is, there was a significantly greater total postoperative blood loss in each of the two groups when cement was not used (p less than or equal to 0.025). A minimum postoperative hemoglobin concentration of ninety-five grams per liter was maintained; a greater percentage of patients (sixteen of twenty-seven) in whom cement was not used needed a transfusion as compared with two of eleven in the group in whom cement was not used (p less than or equal to 0.025), and they also needed more packed red-blood cells (1062 compared with 750 milliliters) (p less than or equal to 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

Aged

Histological examination of the central nervous system in the diagnosis of botulism.

Type C botulinum toxin was given to mice by mouth or intraperitoneal injection. The central nervous system (CNS) of control and affected mice was examined by histological methods such as would be used in a field investigation of botulism. The only change definitely associated with intoxication was microscopic haemorrhage and vascular engorgement; other changes were considered incidental or artefactual. The results are discussed in the light of other descriptions of botulism in animals. It is concluded that non-specific petechiation and vascular engorgement sometimes occur in the CNS in botulism but that the only way routine histology may support a diagnosis of botulism is by exclusion of other diseases.

Administration, Oral

Tips of the trade #13. Tension band wiring of olecranon fractures.

Figure-of-eight tension band wiring is a common method of fixation for displaced olecranon fractures. A modification of this technique, twisting both limbs of the figure-of-eight, has been introduced. A simple technique of performing this modification is described that reduces the chance of wire breakage during application, and permits greater flexibility with associated procedures and ease of revision.

Bone Wires