Search PubMed⌕ Search

Biomedical subjects

M Ozeki

Publications and source records attributed to M Ozeki.

At least 55 records · Page 3Linked to original sources
PubMed1989

[Prosthetic rehabilitation with the removable partial dentures using telescopic crowns after removal of unsuccessful dental implants].

It is well-known that unsuccessful dental implants sometimes give rise to pronounced inflammatory bone resorption of the upper and lower jaw, and that in such cases it is practically much difficult to attain adequate prosthodontic rehabilitation after removal of the implants. On this study it is completely reported that two patients suffering from implant-induced osteomyelitis could be finely compensated for with the removable partial dentures using telescopic crowns after removal of the implants, and then the results are shortly discussed from the view of pathology, oral surgery and prosthodontics. In the first case a 52-year-old woman had been suffering from osteomyelitis of the right mandible due to the both bladevent and endodontic-endosseous implant, and in another case a 43-year-old woman had been suffering from osteomyelitis of the right maxilla due to the endosseous subperiosteal implant, and they had borne insufficient mastication on the affected side of the jaws. Several months after removal of the unsuccessful dental implants, they were rehabilitated with the removable partial dentures using telescopic crowns to recover and maintain good functions such as occlusion, mastication, cosmetics and speech, and oral and general health.

Adult↗
PubMed1989

[Treated case of aortic valve regurgitation associated with Behçet's disease].

Aortic valve replacement was performed to the incompetence of valve cusps with the Behçet's disease. Artificial valve was fixed from the outside of the aortic wall using teflon strips. Satisfactory results were obtained. There are 18 cases of aortic valve regurgitation accompanied with Behçet's disease including this reported case. Not only the aortic valve but also surrounding aortic walls are involved by the inflammatory lesion in Behçet's disease, so that such fixation technique of the prosthetic valve as demonstrated above might be useful. Since Behçet's disease is systemic, progressive and chronic disease, anti-inflammatory treatment with the adrenal steroids is required prior to and after the operation, and there is no distinct method of treatment for Behçet's disease, strict observation of the patient and systemic controls should be recommended continuously.

Aortic Valve↗
PubMed1989

[Successful repair of post-operative rupture of the left ventricular wall after mitral valve replacement].

Rupture of the left ventricular wall after mitral valve replacement (MVR) is a rare but lethal complication, particularly in delayed type. We have encountered five cases of this complication, and the last case who was suffered 6 hours after MVR was successfully repaired. This case is a 56-year-old woman with MS. She underwent MVR with a Duromedics 25 M. She was transferred to the ICU and the postoperative course was uneventful until 6 hours after the operation, then bleeding from chest drainage tubes increased suddenly. She was promptly brought to the operating room, and the cardiopulmonary bypass was restarted. A tear and hematoma at the posterior wall of the left ventricle (Type II perforation) were found. The rupture was closed with three interrupture mattress sutures with a teflon felt strip. Bleeding was decreased, but oppression with sponge was applied to small but continuous bleeding. At present, she is in a good condition without occurrence of pseudoaneurysm of the left ventricle. We investigated our own five cases and sixty cases reported in Japan, and etiology, surgical repair and prevention of this complication were discussed.

Adult↗
PubMed1989

[A case of concomitant association of discrete subaortic stenosis in Kelly type I and hypertrophic cardiomyopathy in early stage].

A 1-year-old baby boy with discrete subaortic stenosis in Kelly type I had coexisting echocardiographic evidence for probably indicating the presence of hypertrophic cardiomyopathy in early stage. At surgery, a discrete subaortic "fibrous membrane" was excised: although the thickening of upper ventricular septum was not thought to be so prominent, the prognosis is related to the natural history of hypertrophied muscle despite successful surgical removal of the subaortic diaphragm.

Aortic Stenosis, Subvalvular↗
PubMed1989

[A clinical study of diltiazem administration using cold glucose-insulin-potassium cardioplegic solution--comparison between diltiazem cardioplegia and diltiazem pretreatment].

A recent idea of myocardial injury during open heart surgery is thought to be caused by the intracellular calcium overload. So, one possibility for improving myocardial protection is expected on the blocking agents of transmembrane calcium movements. This study was designed to clarify the effect of Diltiazem, a kind of calcium blocking agents, on myocardial protection in terms of hemodynamics and plasma Diltiazem concentration. 38 patients who underwent coronary artery bypass grafting using glucose-insulin-potassium cardioplegic solution (GIK) were divided into three groups Control (CO) group: no Diltiazem administration. Diltiazem cardioplegia (DC) group: GIK containing 7.5 mg/l Diltiazem was used. Diltiazem pretreatment (DP) group: Diltiazem was administered intravenously 1.5 micrograms/kg/min before operation to after operation continuously. Plasma Diltiazem concentration was constantly kept at about 150 ng/ml during 24 hours after surgery in DP. On the contrary, in DC, the level was very high (10,000 ng/ml) during aortic cross clamp but decreased about 50 ng/ml at 3 hours after surgery, and Diltiazem was not detected in CO. DC included many cases of bradycardia required pacing, however, it diminished as plasma concentration decreased. Aid of catecholamin administration was reasonable in three groups. DP and DC included many cases of commendable cardiac function in terms of cardiac index, systemic vascular resistance and left ventricular work during acute stage of surgery, and there were no coronary spasm and perioperative infarction. It is concluded that Diltiazem is effective to keep good cardiac function after reperfusion, and combined (Diltiazem pretreatment--1.5 micrograms/kg/min drip infusion-and Diltiazem cardioplegia-total dose 150-300 micrograms/kg) administration should be advisable.

Calcium Channel Blockers↗
PubMed1989

[The use of free rectus abdominis myocutaneous flap to close the empyema space with alveolar fistula--a case report].

A 59-year-old man, who had had right middle and lower lobectomy for pulmonary tuberculosis, admitted for the treatment of empyema with fistula. Closure of empyema space with free rectus abdominis myocutaneous flap was performed following open window thoracotomy and thoracoplasty. As he previously underwent two major operation, lobectomy by posterolateral approach and gastrectomy for gastric ulcer, free rectus abdominis flap was chosen instead of omental flap or latissimus dorsi myocutaneous flap. Postoperative CT film showed that this flap was filled up in all interstices of the empyema cavity. The pedicle vessels to this flap are large enough to provide long stalks, so microsurgical anastomosis can be accomplished safely. The use of free rectus abdominis myocutaneous flap is one of a useful maneuver for chronic empyema with fistula.

Empyema↗
PubMed1988

[Adult neuroblastoma of the adrenal with intraatrial tumor thrombus: report of a case].

A case of adult neuroblastoma of the right adrenal with tumor thrombus extending into the right atrium is reported. Because of right heart failure, the tumor thrombus in the right atrium was removed under the cardiopulmonary bypass. The histopathological examination of the tumor thrombus revealed neuroblastoma. Fourteen days after the first operation, the adrenal tumor, right kidney and tumor thrombus remaining in the vena cava were removed to prevent the recurrence of right heart failure. Two courses of chemotherapy and radiation were given postoperatively and the patient was doing well. Eight months after the second operation, however, the patient died of multiple metastases of the bone and liver.

Adrenal Gland Neoplasms↗
PubMed1988

[Considerations in determining indication for valvular surgery].

Between 1970 and 1987 valvular operations with cardiopulmonary bypass were performed on 636 patients, with an overall early mortality of 7.5%. To determine the critical indication for valvular surgery, preoperative clinical characteristics were examined by comparing 35 patients, who had died of surgery because of low cardiac output syndrome or multiple organ failure, with operative survivors. The multivariable logistic analyses demonstrated that NYHA functional class IV, multiple valvular disease, large CTR more than 70%, high left ventricular end-diastolic pressure more than 15 mmHg, depressed left ventricular ejection fraction less than 40%, and renal and hepatic dysfunction were powerful independent clinical characteristics concerning operative mortality. The mortality was highly significant when a patient was associated with more than three of the above factors in addition to being NYHA class IV. It should be emphasized, however, that there are three survivors among 11 patients with all six factors. On the other hand the prognosis of such patients without surgery was very poor, fifteen of 21 patients, medically treated during the same period, died within two years after reaching NYHA class IV condition. These results show that several predictors are useful for decision making regarding the indication for valvular surgery. Surgery, however, should not be denied because of the severity of the disease.

Heart Valve Diseases↗
PubMed1987

Chondroitin sulfate-depolymerizing activity in Streptococcus intermedius and other streptococci.

The type strain (ATCC 27335) and 18 human oral isolates of Streptococcus intermedius and some other related streptococcal species were tested for chondroitin sulfate C-depolymerizing activity employing a modified screening plate method of Smith and Willett. As the results, S. intermedius strains except for ATCC 31412 strain were found to possess this activity. Propionibacterium acnes ATCC 11828 used as a positive control strain demonstrated strong activity, whereas S. intermedius strains showed only slightly detectable activity. This finding might be interesting in view of the classification of this species as well as its pathogenicity.

Chondroitinases and Chondroitin Lyases↗
PubMed1986

Pharmacological studies of FUT-175, nafamostat mesilate. V. Effects on the pancreatic enzymes and experimental acute pancreatitis in rats.

Effects of FUT-175 on the pancreatic enzymes in vitro and in vivo in the enterokinase-induced experimental acute pancreatitis were investigated, and they were compared with those of gabexate and aprotinin. In in vitro experiments, FUT-175 inhibited the pancreatic protease activities 10 to 100 times more potently than gabexate. Furthermore, FUT-175 inhibited the enterokinase activity. Unlike aprotinin, FUT-175 inhibited alpha 2-macroglobulin bound trypsin activity as well as free trypsin. In in vivo experiments, at doses of 0.5-50 micrograms/kg/min, FUT-175 suppressed the elevated protease activities in the experimental acute pancreatitis more potently than gabexate. Differently from the action of aprotinin, FUT-175 suppressed trypsin activities both in the pancreas and in the plasma to the same extent. Furthermore, FUT-175 reduced the mortality of rats in the experimental acute pancreatitis in a dose-dependent manner. These data strongly support that FUT-175 is clinically useful in the therapy of acute pancreatitis.

Acute Disease↗