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Biomedical subjects

M Osteaux

Publications and source records attributed to M Osteaux.

At least 163 records · Page 9Linked to original sources
PubMed1978

Correlation between liver scintigraphy and computed tomography in the detection of liver metastases.

Parallel scintigraphic and computed tomographic (CT-scan) examinations of the liver were carried out during the same observation period in 55 cancer patients in whom the liver status could be microscopically and macroscopically documented with regard to presence or absence of metastases. Scintigraphy was realized by means of 198Au or 99mTc-colloid using a rectilinear scanner or a gamma-camera; CT-scan images of the liver were obtained by a standard commercial instrument before and after injection of a contrast product. The liver was found to be normal in 38 out of the 55 observed patients and a metastatic involvement was seen in 17 cases. In 45 out of 55 cases, there was concordance between the results obtained by the two investigation methods and discordance in 10 cases. The sensitivity is 97% for the scintigraphy, 94% for the CT-scan and 100% for the common negative results. The specificity can be established as 64% for the scintigraphy, 65% for the CT-scan and 74% for common positive findings. It seems therefore that these two techniques present the same efficiency in the detection of liver metastases and that the results obtained are only partly complementary.

Female↗
PubMed1977

The management of anterior sacral meningocele with computed tomography.

This report concerns a case of anterior sacral meningocele (ASM) with an evaluation of the diagnostic reliability of the CT scan for the management of this condition and others concerning the vertebral column and pelvis. This technic makes a precise preoperative survey possible by the direct demonstration of the lesion and its extension, by the measurement of its density and by the visualization of its pedicle, as well as easy and atraumatic postoperative control. ASM is a congenital meningeal cyst, herniating through a bony defect of the sacrum. It often remains undetected, since it is a rather rare condition and difficult to visualize with simple diagnostic procedures. An early diagnosis of this basically benign condition is nevertheless very important, because of the serious pitfalls that may arise.

Adult↗
PubMed1977

[Study of the liver by computerised tomography. Assessment of one years experience involving 1,480 investigations (author's transl)].

During a period of one year, and in two departments with identical equipment, 1,480 underwent examination of the liver by computerised tomography (C. T.). A critical analysis of the method is made, based upon the diagnostic results obtained as well as the errors and gaps noted. After describing the normal liver, the authors give the "C. T. appearances" of the main hepatic conditions, based upon correlation with macroscopic pathological findings.

Cysts↗
PubMedDate not supplied

Absolute quantification of 31P liver metabolites in rat using an external reference and a surface spoiling magnetic field gradient.

A simple method for measuring absolute concentrations of 31P metabolites in rat liver using an external reference is described. It neutralizes systematic errors due to conductive losses by calibration of the matching capacitor and selects liver signals via an electrically driven, surface spoiling magnetic field gradient. The technique avoids the chemical shift problems associated with linear field gradient localization methods at 4.7 T and allows combination with the double standard method for absolute metabolite concentration determination. Application of the method to the in vivo measurement of the absolute concentrations of ATP and P(i) in eight rat livers yields results that are in good agreement with literature values. Absolute phosphomonoester concentrations were also obtained, but no literature data were available.

Adenosine Triphosphate↗
PubMedDate not supplied

Inverted Meckel's diverticulum as a leading point for ileoileal intussusception in an adult: case report.

Intussusception due to an inverted Meckel's diverticulum is considered a rare occurrence. We present a case of a 37-year-old male with anemia and melena due to an inverted Meckel's diverticulum at the base of an ileoileal intussusception. To our knowledge, this is the first case in which small bowel enema, computed tomography, and magnetic resonance imaging showed the pathology.

Adult↗
PubMedDate not supplied

Determination of liver volume in vivo in rats using MRI.

Accurate estimation of the liver volume may be important for the diagnosis of several pathological processes in patients and for the study of new therapies in experimental oncology. Although sonography and computed tomography (CT) have been used for this purpose in patients, the lack of spatial resolution and tissue differentiation is a source of measurement errors which, at present, makes it impossible to accept sonography and CT widely for the determination of the liver volume. In the present study, the liver volumes of seven rats were measured by magnetic resonance imaging (MRI) and an automated image analysis system before and after the animals were killed. Volume computation was carried out by adding up the individual volumes in the sequential MR sections. Adequate MR images with high contrast between the liver and surrounding structures were obtained with spin echo pulse sequence and retarded phase encoding while no contrast material was used. The mean volumes of the livers measured by MR in vivo and in cadavers were 11.91 +/- 0.40 and 11.92 +/- 0.45 ml, respectively. When compared with the actual liver volumes measured in vitro after resection, the errors of determinations in vivo and in cadavers were as small as 3.1 and 2.1%, respectively. These data indicate that MR imaging is an accurate means to determine the liver volume in vivo and that it may be potentially useful to measure small intrahepatic lesions in patients.

Animals↗