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Biomedical subjects

M Onerci

Publications and source records attributed to M Onerci.

At least 37 records · Page 2Linked to original sources

Audiological findings in kernicteric patients.

Audiological findings in kernicteric patients. Thirty patients followed up because of kernicterus sequelae and 15 normal children serving as control group were examined to determine their hearing status and evoked response audiometry (ERA) results. Seventeen out of the 30 patients (57%) had high frequency sensorineural hearing loss. Sixteen of them had bilateral hearing loss. Ten had no response or prolonged bilateral latencies. The results showed that high neonatal serum bilirubin levels affect the hearing adversely.

Adolescent↗

Pneumatised superior turbinate: a common anatomic variation?

Anatomic variations are important in preendoscopic CT evaluation of the paranasal sinuses. In this study, we investigated whether the superior turbinate could become pneumatised like the middle turbinate, pneumatisation of which is well-known. Images of 52 patients who underwent CT examination prior to endoscopic sinus surgery and who had normally aerated posterior ethmoidal cells and an unobscured nasal cavity were retrospectively evaluated. The patients were 12-68 years old (median age, 35 years); 28 were women and 24 were men. Pneumatisation of the superior turbinates was graded in two groups as minimal or marked. Pneumatisation was evident in 25 patients (48%). 13 unilateral (25%), 8 bilateral (15%) pneumatisations were detected in the group graded as minimal, whereas 1 unilateral and 3 bilateral pneumatisations were present in the markedly (8%) pneumatised group of patients. Superior turbinates were seemingly aerated through the posterior ethmoid cells. The superior turbinates can be pneumatised as the middle turbinate is a not frequent anatomic variation that should be taken into account in preendoscopic CT evaluation of the paranasal sinuses.

Adolescent↗

Evaluation of the microbiology of chronic sinusitis.

Chronic sinusitis is one of the most common diseases treated in outpatient centres. In this prospective study, 49 patients with the diagnosis of chronic maxillary sinusitis were evaluated microbiologically by using sinus swab, irrigation fluid and sinus mucosal tissue specimens obtained during endoscopic sinus surgery. There was no bacterial growth in seven cases. In the remaining 42 cases a total of 89 bacteria were isolated, 28 of them being classical pathogens and 61 being non-classical pathogens. Among the classical pathogens Staphylococcus aureus was the most common one. The correlation between the isolates obtained from maxillary sinus and isolates obtained from throat, nose and nasopharynx did not have a predictive value. Since the overall rate of classical pathogen isolation from patients with chronic sinusitis was not significantly high, the possible role of factors other than bacterial growth should be identified in the pathogenesis of chronic sinusitis.

Adolescent↗

[Aneurysmal bone cyst of the mandible].

BACKGROUND: Aneurysmal bone cysts are benign lesions of bone consisting of a septated, cystic cavity filled with non-endothelium-lined, blood-filled spaces. Aneurysmal bone cysts mainly occur in children and adolescents. Only a few occur in the jaws. PATIENT: This is the report of a 9-year-old girl with an aneurysmal bone cyst in the condyle of the mandible who was admitted to the hospital with swelling in front of her right ear. Because of the location and to eliminate recurrence, complete surgical excision of the condyle was performed. DISCUSSION: Fifty-seven cases of aneurysmal bone cyst of the mandible have been reported to date. Aneurysmal bone cyst is treated by surgical excision, which ranges from enucleation and curettage to conservative resection. CONCLUSION: Simple curettage for aneurysmal bone cyst is reported to be associated with a high recurrence rate, a result of the difficulty of completely excising such a vascular lesion. We recommend complete surgical excision as the best treatment.

Bone Cysts, Aneurysmal↗

Trace elements in chronic sinusitis.

Trace elements are indispensable for life and play an important role in the immunological system. Since it is believed that serum trace element values decrease in chronic infections, 43 patients with chronic sinusitis were evaluated for Zn, Mg and Cu levels. While all trace elements were found to be within normal ranges, Cu values were found to be significantly lower than in a control group of 20 age- and sex-matched volunteers. The reasons for this are unclear in the present study.

Case-Control Studies↗

The effect of tonsillectomy on neutrophil chemotaxis in adults with chronic tonsillitis.

Neutrophil random motility and chemotactic responsiveness were determined in 17 healthy adults and 19 adult patients with chronic tonsillitis before and 10 days after tonsillectomy, using a modified Boyden chamber method. The mean chemotactic index values of the healthy controls were significantly higher when compared with the chronic tonsillitis patients before tonsillectomy. The postoperative mean chemotactic values were increased, and there was a statistically significant difference between the mean chemotactic index of neutrophils in preoperative and postoperative patients. The authors conclude that this change in host defense mechanism may be the reason for frequent attacks of acute tonsillitis in these patients.

Adult↗

Shortcomings of lateral sinus radiograph in the preoperative determination of the extent of endonasal endoscopic sinus surgery.

Lateral sinus radiograph is helpful in determining the distances between certain anatomic landmarks in preparation for endonasal endoscopic sinus surgery. However, some misleading factors limit the usefulness of this radiograph. In this study these distances were measured in 49 patients and compared with measurements obtained from another imaging modality, magnetic resonance imaging, which provides more accurate measurements. Results show a discrepancy in the measurements of distances between some of these landmarks that cannot be explained by the factor of magnification alone on the sinus radiographs. Statistical analysis of the results for women revealed a significant discrepancy between the distances from the nasal spine to the midfovea ethmoidalis, the sphenoethmoid junction, and the posterior sphenoid wall as measured on MR images and those as measured on lateral sinus radiographs (P < .05). For men the same was true for the distances from the nasal spine to the midfovea ethmoidalis and the posterior sphenoid wall (P < .05). It is concluded that there should be reservations in the surgical application of data provided by the lateral sinus radiograph before endoscopic sinus surgery.

Adult↗

Evaluation of leukocyte chemotactic function in patients with chronic sinusitis.

In this study the chemotactic activities of neutrophils and monocytes were evaluated in patients with chronic sinusitis as compared to a control group. Leukocyte chemotaxis was measured with a micropore filter method in blood samples taken from 26 patients with chronic sinusitis and 10 volunteers. A statistically significant impairment of leukocyte chemotaxis capacity in patients with chronic sinusitis was found. It is concluded that a functional disorder of leukocytes may play a role in the progression of the disease into a chronic state.

Adolescent↗

The effect of a new ostium and sinus mucosal flaps on mucociliary flow of the maxillary sinus.

To evaluate the effect of a new ostium upon the mucociliary flow of the maxillary sinus, a window in the lateral wall of the sinuses was made and left open in New Zealand rabbits. The contralateral sinuses were used as controls. No change in mucociliary flow was observed, except for a shorter clearance time in sinuses with a new ostium. In the second group of rabbits the maxillary sinus mucosa was elevated at the floor, lateral and medial walls and rotated about 80-90 degrees. The other side acted as control, the mucosa was elevated and put in place again. The mucociliary flow of sinuses with rotation decreased significantly.

Animals↗

Audiologic and impedancemetric findings within thalassaemic patients.

The objective of this study is to investigate hearing losses in thalassaemic patients. This study was conducted on 34 thalassemic patients of which 27 of them had thalassaemia major and the remaining 7 had thalassaemia intermedia. Six (11.11%) of the 54 ears with thalassaemia major were found to have normal hearing. Thirty-two ears (59.26%) had conductive hearing loss, 8 ears (14.81%) had mixed type of hearing loss. Moreover, in this group, there was no ear which had pure sensorineural hearing loss. Of the majority of patients having thalassaemia major and thalassaemia intermedia, an air bone gap was found even though there was no negative pressure in the middle ear. In these patients a high degree of static compliance and normal shaped, stiff amplitude, normal pressure tympanograms were observed. Moreover, in most of these patients acoustic reflexes were not obtained. These findings are rather interesting since they show the pathological changes which may cause stiffness in the middle ear sound transmission system.

Acoustic Impedance Tests↗

Lymphoma with bilateral cavernous sinus involvement in early childhood.

A 4-year-old girl developed complete ophthalmoplegia with intact pupillary responses. Computed tomography and magnetic resonance imaging demonstrated a mass invading the cavernous and sphenoid sinuses and posterior ethmoidal cells. Biopsy revealed non-Hodgkin lymphoma. This patient is the youngest reported with malignant lymphoma of the cavernous sinus and the second reported with bilateral cavernous sinus involvement.

Antineoplastic Combined Chemotherapy Protocols↗

Synovial sarcoma in the neck.

Synovial sarcomas are very uncommon and highly malignant tumours. This uncommon malignant tumour of mesenchymal origin may rarely present in the neck. Since 1954, nearly 80 cases of synovial sarcoma, located in the head and neck region have been reported. Synovial sarcoma is most prevalent in adolescents and young adults between 15 and 40 years of age. In this report we present a case of synovial sarcoma in the neck of a 10-year-old patient.

Child↗

[Oropharyngeal anthrax].

We report on a 46-year old man suffering from the oropharyngeal form of human anthrax. The patient presented with a sore throat and extensive swelling of the right neck, the oropharynx and especially the right tonsil. The skin of the mandibular and submandibular region showed vesicular lesions followed by ulcerations resulting in a blackish eschar. The diagnosis was verified by bacteriological culture. Thus, in cases of known exposure, in areas where anthrax is endemic or in immigrant workers coming from such areas, infection with bacillus anthracis should be included in the differential diagnosis of inflammatory oedematous lesions of the oropharynx.

Animal Husbandry↗

Liposarcoma of the cheek: report of a case.

Liposarcomas of the head and neck region are rare. Those originating in the buccal mucosa cause special diagnostic and therapeutic difficulties. In this report, a predominantly well-differentiated liposarcoma of the cheek in a 32-yr-old man is reported. The tumor continued to grow slowly over a period of 3 yr before definitive diagnosis was established. Radical maxillectomy was performed with total excision of the tumor. Recommendations for earlier and correct diagnosis and treatment of this rare neoplasm are discussed.

Adult↗