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Biomedical subjects

M Okuni

Publications and source records attributed to M Okuni.

At least 73 records · Page 4Linked to original sources
PubMed1977

A trial of phono-cardio-scan (PCS) for the detection of the heart disease in preschool and school children [proceedings].

An attempt of PCS was performed for the first time in Japan. Eighteen hundred twenty-six preschool and school children were examined and the result was compared with other studies (physician's auscultation and PCG). The time requirement for a single child is approximately 1.5 min. in primary school. It took longer time in kindergarten. The heart murmur detection rate is high and the sensitivity is fairly good, although it is not so good as well-trained physician's heart murmur detection rate. PCS is not perfect, but is fairly good tool for screening. It can be used only by technician. PCS may be able to save the physician's time.

Child↗
PubMed1976

Effect of steroid hormone on rheumatic carditis.

One hundred and eleven patients with rheumatic carditis of the first attack were treated with steroid hormone. In the cases, in which the steroid hormone therapy started within 2 weeks from the onset of the disease, all except one did not reveal a residual valvular heart disease after 2 years from the treatment. It was suggested that early diagnosis and the earliest start of steroid hormone therapy with large dose on rheumatic carditis is necessary for the prevention against development of rheumatic heart disease. A therapeutic schedule for rheumatic fever is recommended.

Heart Murmurs↗
PubMed1975

Studies on myocarditis in childhood, with special reference to the possible role of immunological process and the thymus in the chronicity of the disease.

Twenty-one cases of idiopathic myocarditis were studied. Fulminant form 1 case, acute fatal form 2 cases, acute benign form 4 cases, recurrent form 1 case. Chronic dilated form 2 cases progressive hypertrophy form 2 cases and asymptomatic and sudden death form was 10 cases. Clinical signs and symptoms of these cases were manifold. Also laboratory findings were nonspecific. Ten cases of latent myocarditis which showed sudden death syndrome were found among 47 cases, progressive hypertrophy form 2 cases and children. Early detection of latent myocarditis is considered to be necessary for preventing sudden death syndrome in school children. The relationship between cardiomyopathy and idiopathic myocarditis was discussed. Two cases of idiopathic myocarditis simulating cardiomyopathy were presented. The pathogenesis of chronicity in idiopathic myocarditis was discussed. Bound gammaglobulin in heart muscle was detected in a case showing progressive hypertrophy of the ventricles. Autopsy results showed a previously undescribed finding that the cases having normal thymus/body weight ratio tended to have markedly increased heart weight but the cases having increased thymus/body weight ratio tended to have near normal heart weight. These results are considered to suggest the possible role of immunity in the chronicity of idiopathic myocarditis.

Adolescent↗