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Biomedical subjects

M Okuni

Publications and source records attributed to M Okuni.

At least 37 records · Page 2Linked to original sources

[Support system for the demented elderly--the viewpoint of community care].

Judging from the features of senile dementia, it is desirable for the demented elderly to receive care at their places to which they are accustomed and to be surrounded by affectionate families, if possible. Year by year, however, sufficient intrafamilial care is becoming more and more difficult because of increasing numbers of nuclear families, women's into society, the deteriorating housing situation and the like. Accordingly, the importance of community care is increasing; an integrated care system with close cooperation of medical facility services and at-home services needs to be established. Three important measures; i.e. home helper dispatching, short stay activity and day service activity as well as close cooperative work for health activities, medical care and welfare are still far from satisfactory, though these problems have begun to be tackled actively. Various types of advanced models and regional network systems exist fulfilling several necessary conditions for effective functioning. The need of a three-layer structure was emphasized based on a practical study of Matsubara City, Osaka.

Aged↗

Serum content of zinc and vitamin C in severely handicapped children.

As fracture is known to occur more easily in severely handicapped children (SHC), bone mineral content, serum zinc level and serum vitamin C level were determined in 65 SHC. These parameters were found to be greatly reduced in all patients. The decreases in zinc and vitamin C in the serum appeared to be associated with that in bone mineral content. Supplements of zinc and vitamin C may be important to decrease the chance of fracture due to diminished bone mineral content in SHC.

Adolescent↗

Sudden death of school children in Japan.

The autopsy findings of sudden deaths of school children revealed that the main causes of death were latent myocarditis and arrhythmia, followed by idiopathic cardiomyopathy. The incidence of sudden death of school children in recent years is gradually increasing and 150 cases of sudden death occurred during the 1983 school year. A high incidence of sudden death in senior high school students was found. Sudden cardiac death accounted for approximately 80% of total deaths. The incidence of sudden cardiac death revealed prominent regional differences in Japan. The average for deaths was 0.40/100,000 children/5 years and the highest prefecture revealed 0.70 and the lowest 0.07. The cause of such differences is not clear and requires further analysis.

Adolescent↗

Treadmill exercise test in children with cardiomyopathy and postmyocarditic myocardial hypertrophy.

The treadmill exercise test with the Bruce protocol was performed in three patients with post-myocarditic myocardial hypertrophy (PMH) and ten patients with cardiomyopathy, including three with dilated cardiomyopathy (DCM), five with hypertrophic obstructive cardiomyopathy (HOCM), and two with hypertrophic and nonobstructive cardiomyopathy (HCM). The endurance time was below the normal level in all but one case and was normal or near normal in the three cases with PMH. ST depression was observed in five cases, none of which were of HCM. A marked increase in amplitude of the negative phase of the P wave in V1 was observed in one patient with DCM. The response of blood pressure during the exercise was abnormal in patients with DCM and HCM but was normal in PMH.

Adolescent↗

Effects of fatness on the electrocardiogram in children aged 12-15 years.

Using the 4-Lead Set Japanese Pediatric ECG Screening Criteria Proposal, the effects of fatness on the electrocardiograms were analyzed in 1025 junior high school children, aged 12-15 years (of whom 114 were obese). As the results show, significant differences were detected by the 1% two-sided test between the averages of the nonfat group and the middle- and high-fat groups with regard to S amplitude in leads V1-V3 for boys and girls, R amplitude in leads V4 and V5, SV1 + RV6, SV1 + RV5, and SV3 + RV3 for boys, and S amplitude in leads V4-V6 for girls. High R amplitudes were observed in leads V3 and V4 for the middle- and high-fat group of girls. When applying conventional ECG criteria for left ventricular hypertrophy to the middle- and high-fat groups of boys, the value of SV1 + RV6 greater than or equal to 4.5 mV instead of SV1 + RV6 greater than or equal to 5.0 mV is recommended.

Adipose Tissue↗

Cardiomyopathy and myocarditis in children.

Five cases of postmyocarditic change with clinical profiles of cardiomyopathy in children are described. Some cases with a history of acute myocarditis show postmyocarditic hypertrophy, which may be related to certain immunologic processes. Others with no apparent clinical history of acute myocarditis present with a clinical picture of hypertrophic cardiomyopathy and show improvement. Based on long-term observation, these cases are considered to represent postmyocarditic hypertrophy. Long-term follow-up with full laboratory examination, including endomyocardial biopsy is considered necessary in establishing the final diagnosis.

Acute Disease↗

Abnormal Q-wave in children. The first report: QS-pattern in lead V1.

Seventeen healthy children with QS-pattern in lead V1 were studied vectorcardiographycally. Age ranged from 6 to 15 years old. Azimuth at 10 and 20 msec displaced leftward and azimuth of maximum spatial voltage slightly displaced posteriorly. Anterior component was minimal. QS-pattern in lead V1 in children is not necessarily abnormal finding. The main cause of QS-pattern in lead V1 is electrical rotation of the heart.

Adolescent↗

Serum HDL-cholesterol and lipoprotein fraction in Kawasaki disease (acute mucocutaneous lymph node syndrome).

Serum HDL-cholesterol level and lipoprotein fraction were studied in 50 patients with Kawasaki disease (acute mucocutaneous lymph node syndrome), ranging in age from 4 months to 7 years, with an average of 2 years and 6 months. There were 31 males and 19 females. In 7 of these patients coronary arterial aneurysms were revealed by aortogram. In all 50 patients analysis were carried out periodically from the onset of the disease to the convalescent stage, and the following results were obtained: 1) Serum total cholesterol level showed mild change throughout the course of the disease. 2) Average HDL-cholesterol level was 29.6 +/- 11.0 mg/dl in the first week of the disease, 26.8 +/- 8.9 from 1 to 2 weeks and 47.9 +/- 12.6 after 6 weeks. There was significant difference between the HDL-cholesterol levels of first 2 weeks and after 4 weeks (p less than 0.01). 3) The recovery of HDL-cholesterol level was slow in both clinically severe patients and the patients with coronary aneurysms as compared with that in clinically mild patients (p less than 0.05). These findings suggest that there may be some relationships between the alteration of serum lipoprotein and the severity of systemic vasculitis in Kawasaki disease, especially which may play some role in clinical severity and the occurrence of coronary arterial lesions. However, further study is needed to clarify the cause of changes in serum HDL-cholesterol and lipoprotein.

Child↗

Development of a heart disease screening system for school children and its results in the Tokyo area in 1980.

After the revision of the School Health Law in Japan the systems for heart disease screening for school children showed a great advance and the computerized devices for automatic evaluation of selected leads ECG and PCG were developed rapidly and have been improved in Japan. Two systems of heart disease screening for school children have been developed, that is, the Tokyo system and the "ECG-PCG for all children system". The Tokyo system utilizes a questionnaire, a physical examination by school physicians and a chest X-ray for the primary screening procedure and ECG-PCG for the secondary procedure. The "ECG-PCG for all children system" utilizes a questionnaire, a chest X-ray and ECG-PCG. The superiority of the ECG-PCG system was shown in comparison with the Tokyo system. Nearly twice as many cases of congenital heart disease were detected by the ECG-PCG system as compared with the Tokyo system, and many cases were disclosed for the first time. The "ECG-PCG for all children system" will probably be more popular in the near future in accordance with the advance of computerized systems.

Adolescent↗