Cross resistance against challenge infection in mice infected with Trichinella spiralis or T. pseudospiralis.
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Biomedical subjects
Publications and source records attributed to M Ohbayashi.
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Gnathostoma malaysiae Miyazaki and Dunn, 1965 was found in the stomach wall of Rattus surifer, captured in Phuket Island and Khao Yai National Park of Thailand. This is the first to be recorded in Thailand and the second discovery after the first description of Miyazaki and Dunn (1965). Pathological findings of infected animals were also described. Some new morphological descriptions were added to the original.
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A 58-year-old female was admitted to our hospital because of weakness of the right lower extremity and dysesthesia of the right upper extremity. From her clinical symptoms the patient was tentatively diagnosed as having a sort of cerebral infarction and treated with administration of urokinase and antiplatelet agents. However, angiographical examination revealed a unruptured aneurysm of the A1 portion of the left anterior cerebral artery. Preoperative angiogram showed that the dome of the aneurysm compressed one of the neighboring perforating artery which arose from adjacent to the neck of the aneurysm. The patient underwent neck clipping of aneurysm successfully. During the operation, the perforator was hardly adhered to the dome of the aneurysm. So, careful dissection was made only around the neck and the perforator was spared. Her symptoms were disappeared immediately after surgery. The perforator was demonstrated with better filling in the postoperative angiogram than that in the preoperative angiogram. The pathomechanisms of cerebral ischemia caused by unruptured aneurysm were reviewed on the literature. Most of the cases were caused by release of fragmental thrombi from a large aneurysm. There was a very exceptional case whose symptoms had seemed to be related to the direct compression of the neighboring perforator by the aneurysm. The compressed perforator in this case was seemed to be corresponded with the medial proximal striate artery stated by Yaşargil.
Eosinophil infiltrations were observed in the intestine and the muscle of both Trichinella spiralis-infected (WBxC57BL/6)F1-W/Wv mice and their littermates, WBB6F1-+/+, +/W, +/Wv, almost to the same extent. W/Wv mice did not show infiltration of subepithelial mast cells and globule leucocytes in response to T. spiralis infection. Increased numbers of these cells were observed in their littermates. Worms in W/Wv mice were retained for longer periods than those in littermates. Also, no difference was noted in the production of specific serum antibodies between W/Wv mice and their littermates, as determined by passive cutaneous anaphylaxis (PCA) for specific IgE and by indirect haemagglutination (IHA). These results suggest a possible participation of SMC, GL and eosinophils in the expulsion of adult T. spiralis.
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A rare case of massive gastrointestinal bleeding from ileal varices was reported. On December 28, 1982, a 49-year-old male was admitted to Kurashiki Central Hospital because of massive gastrointestinal bleeding. Eleven years ago, the patient underwent an emergency operation for rupture of esophageal varices. The venous phase of selective superior mesenteric and celiac angiography showed mesenteric varices, but no definite bleeding point was noted. Endoscopy revealed esophageal varices, but no area of bleeding was encountered. Because of frequently repeated hemorrhages, laparotomy was performed. A large vein was found on the surface of the ileal wall, through an adhesion to the lateral pelvic wall. Partial resection of ileum was performed. Histological examination of the resected small bowel demonstrated ruptured submucosal varices. The postoperative course was uneventful and he was discharged on the 40th postoperative day. It is stressed that this disease should be considered as a differential diagnosis for a patient with lower gastrointestinal bleeding and portal hypertension.
Paratype material of Echinococcus cruzi Brumpt and Joyeux, 1924, described from an agouti, Dasyprocta leporina (L.), in Brazil, was compared with Echinococcus oligarthrus (Diesing, 1863), of which the larval stage occurs also in agoutis and other rodents in South America and Central America. Comparisons of the larval cestodes (metacestodes) showed that the rostellar hooks from protoscolices of the two taxa corresponded in form, and their slightly greater lengths in E. cruzi were considered to be of no taxonomic significance. They agreed as well in other morphological characteristics. Echinococcus cruzi was compared also with the other neotropical species, E. vogeli Rausch and Bernstein, 1972, Based on these comparisons and in agreement with the earlier conclusion of Cameron (1926), E. cruzi Brumpt and Joyeux, 1924 is placed in synonymy with E. oligarthrus (Diesing, 1863).