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M Ogiwara

Publications and source records attributed to M Ogiwara.

54 records · Page 3Linked to original sources
PubMed1991

[The relation between ECG findings and lesions of acute and old myocardial infarction in autopsy cases].

Sixty-four elderly autopsy cases with acute myocardial infarction (AMI) were investigated in Nagoya Koseiin Geriatric Hospital. First AMI was observed in 35 cases, and recurrent AMI in 29. The primary causes of death were cardiac rupture and congestive heart failure in the first AMI and the recurrent AMI, respectively. The most frequent ECG findings before AMI were ischemic ST-T-change (57%) and Q-QS abnormality (41%) on the first and recurrent AMI, respectively. The ECG findings were normal in 6 (21%) of 29 recurrent MI cases. There was a tendency towards Q-QS abnormality in large size old MI, but not in small size MI. In 29 cases with recurrent AMI, the positional relationship between the old MI and the AMI was classified into 3 groups of different area, same area, and different and same area according to the Maccarie classification. The frequency in our cases was similar in the 3 groups. Ten cases with different area were further classified into 3 groups, i.e. opposite, adjacent, and opposite and adjacent. Opposite cases consisted of 4 (40%) cases, while opposite and adjacent consisted of 6 (60%). It is suggested that the recurrent AMI is more likely to be fatal when AMI occurs opposite to a previous lesion rather than adjacent to an old lesion.

Aged↗
PubMed1991

[Three cases of Meige syndrome treated with facial nerve block].

Three cases of Meige syndrome with severe bilateral facial spasm were reported. All patients suffered from abnormal facial movement characterized by blepharospasm and oromandibular dystonia, and had atrophic changes of bilateral basal ganglia which were recognized by brain CT scan. Bilateral facial nerve block at the foramen stylomastoideum was applied to those three patients. Excellent results were obtained by this block technique in all the patients. The technique is not so sophisticated and is recommended for the treatment of the patient with Meige's syndrome.

Aged↗
PubMed1989

[Temporal changes in internal echoes in hepatic hemangiomas].

We have discovered a fact that there is a temporal changes of internal echo levels in hepatic hemangiomas. Nine hemangiomas in 6 cases diagnosed by CT were studied ultrasonographically by the real-time scanner during the observation period from 4 to 30 minutes. Low echo portions occupying within the tumor (low echo level ratio) showed temporal changes in 8 of 9 hemangiomas during this period. It is important to take temporal factors into consideration for the ultrasonographic diagnosis of hepatic masses. We coined the term "wax and wane" sign to the temporal changes of internal echo levels in the hepatic hemangioma.

Adult↗
PubMed1989

[A clinicopathological analysis of cardiac rupture following acute myocardial infarction in elderly patients].

In all autopsied cases from January 1980 to June 1988 (56-102 years old, 243 men and 307 women), cardiac rupture death was observed in 14 cases out of 68 deaths of acute myocardial infarction in our hospital. Cardiac rupture occurred in 2, 4, 3, and 5 cases in their 60's, 70's, 80's, and 90' respectively, and 4 in men and 10 in women. Complaints of chest pain were present in 4 cases. Cerebrovascular disease was present in 9 cases and hypertension in 7. In 9 cases, the thickness of the ruptured wall was over 14 mm. The location of the ruptured lesion was the anterior wall in 4 cases, anteroseptal in 3, anterolateral in 1, lateral in 1, posterior in 1, and apical in 1. In conclusion, the incidence of cardiac rupture was higher in female than in males, and in silent myocardial infarction than in painful one. The location of rupture was frequently in the anterior or lateral wall. Aging and hypertension would not be a worsening factor in the pathogenesis of cardiac rupture in myocardial infarction, but cerebrovascular disease might be a risk factor in respect to masking occurrence of myocardial infarction.

Aged↗
PubMed1984

Clearance and maximum removal rate of liposomes in normal and impaired liver of rat.

In the present study the author described a new method for analysis of the reticuloendothelial system (RES) function, using blood clearance of liposomes containing encapsulated phenolsulfonphthalein as a marker. Various types and doses of liposomes were intravenously administered to rats and the clearance of liposomes from blood was observed. Large liposomes were cleared from blood at a faster rate than small ones. Large liposomes composed of phosphatidylcholine and cholesterol were mainly phagocytized with Kupffer cells. The rate of disappearance of liposomes from blood was able to be calculated. With increments of administered doses there was an associated decrease of the disappearance rate, which corresponded to the Lineweaver-Burk plot in the enzymatic process, and it was possible to calculate the maximum removal rate and Michaelis constant. Disappearance rates decreased after prior administration of large liposomes and the inhibitory mode was competitive. Disappearance rates decreased after pretreatment with dextran sulfate and the inhibitory mode differed from the competitive. In partially hepatectomized and CCl4 intoxicated animals, disappearance rates also decreased. Liposomes are easily prepared and non-toxic. The clearance test of liposomes is possible to evaluate the role of the phagocytic function of the RES, chiefly Kupffer cells, in various experimental and clinical conditions.

Animals↗
PubMed1984

[A study of multiple primary cancers of the stomach and other organs].

The incidence of associated synchronous or heterochronous malignant tumors in this series was 3.3% (21/633). These patients were found more in multiple cancer than single cancer of the stomach. A relatively high incidence of associated cancer of other organs was found with cancer of the large bowel and of the cervix in heterochronous cancer and cancer of the esophagus in synchronous tumors. The cumulative corrected 10-year survival rate of 15 cases of heterochronous tumors was 85.7%. On the other hand, six patients with synchronous tumor had more advanced cancer of other organs than gastric cancer, and four of them died due to cancer of other organs within two years. Both primaries should be found at the early stage and treated with curative surgery and/or radiotherapy.

Colonic Neoplasms↗
PubMed1984

Effects of surgical treatment and adjuvant chemotherapy studied by the depth of penetration in gastric cancer patients undergoing curative gastrectomy.

This report concerns 133 of 377 patients with gastric cancer who underwent curative gastric resection at the First Department of Surgery, Shinshu University Hospital, between January 1, 1967, and December 31, 1975. The effects of surgical treatment and adjuvant chemotherapy were investigated for every depth of penetration into the gastric walls. The 5-year survival rate was 41.7% among patients subjected to gastrectomy and 61.7% among those treated by curative gastrectomy. The 5-year survival rate decreased along with increased depth of invasion. Following surgical treatment, the 5-year survival rate was higher in the patients who underwent absolute curative resection than in those who were subjected to relatively curative resection. Extended radical gastrectomy is needed for patients with the depth of invasion through the muscularis propria. It is necessary to complement chemotherapy for patients with lymph node metastasis who are subjected to relative curative gastrectomy. In the patients with serosal invasion, papillary and tubular adenocarcinoma decreased and poorly differentiated adenocarcinoma increased substantially. The patients with poorly differentiated adenocarcinoma had a poorer prognosis than did those with tubular adenocarcinoma. Some ideas for the treatment of poorly differentiated adenocarcinoma are earnestly hoped for.

Adenocarcinoma↗
PubMed1984

[Clinico-pathological study and surgical treatment of cancer of the greater curvature of the stomach].

We retrospectively studied the clinicopathological features and surgical treatment of patients with cancer of the great curvature seen between 1967--1977. The incidence of cancer of the greater curvature in gastrectomized patients was 11% (31/281): this was the least frequent of four locations. Curatively resected patients, the five-year survival rate of those with cancer of the greater curvature was 50%, significantly lower than in patients with cancer of the anterior and posterior wall. Factors influencing the survival rate were age, size of the tumor, stage of the cancer, the presence of poorly differentiated adenocarcinoma, and relative curative resection. To improve the results of surgical treatment, early diagnosis and extended lymph node dissection are essential.

Adenocarcinoma↗
PubMed1982

[2,8-Dihydroxyadeninuria: 2.8-dihydroxyadenine crystals in urinary sediment in patients with adenine-phosphoribosyltransferase deficiency].

A girl had frequent ureteric infections from the age of three years onwards, passed 2.8-dihydroxyadenine ureteric stones and was in renal failure. At six years of age she was without symptoms, but even during this stage characteristic round crystals of 2,8-dihydroxyadenine were found in the urinary sediment. Activity of adenine-phosphoribosyltransferase (A-PRTase) in red blood cells was markedly diminished to 4.5% of normal values. Crystal excretion was inhibited by allopurinol. These findings suggest that it may be possible to detect cases of considerable A-PRTase deficiency and thus prevent the development of stones and renal insufficiency.

Adenine↗
PubMed1979

Surgical treatment of the radiation injured bowel.

Over the last 10 years, 9 patients treated by surgical procedure for radiation injuries of the bowel were studied with the following conclusions: The damage to the small intestine caused by external irradiation leads to adhesion of the bowel, perforation and postoperative anastomotic dehiscence if the irradiated bowel is used in the anastomosis. Surgical treatment for the small intestine is resection of the damaged loop. In order to determine the extent of the resection it is important that during the operation fibrosis and obstruction of vessels in the submucosa and subserosa is examined by biopsy. On the other hand, rectal ulcer and/or rectovaginal fistula is chiefly caused by intracavitary application plus external irradiation. For these lesion Hartmann operation or colostomy is performed, and the postoperative course is uneventful.

Adult↗