Biomedical subjects

M Ochodnický

Publications and source records attributed to M Ochodnický.

At least 19 recordsLinked to original sources

PubMed1994

[Renal excretion of calcium in healthy persons].

The authors examined the calcium excretion in a group of 100 healthy subjects (50 men and 50 women) aged 21-40 years. Urine was collected under ambulatory conditions. Calcium excretion was expressed as Ca excretion per minute, Nordin's index, calciuria/GF.1.73 m2 and the renal threshold for calcium. Calcium excretion per minute was significantly lower in women, as compared with men. This significant difference of mean values of calcium excretion per minute persists when the subjects are classified by sex and age groups. Women aged 31-40 years had a significantly lower calciuria/GF.1.73 m2 than men aged 21-30 years and a significantly higher renal threshold for calcium, as compared with men of equal age. If standard conditions of urine collection are respected, the mentioned examination method can be used during ambulatory examinations of patients with impaired calcium and phosphate metabolism. The assessed values of different indicators must be, however, compared with values of healthy subjects of the same age and sex.

Adult↗

PubMed1993

[Relation between morphometric indicators in axons of myelinated peripheral nerve fibers and the age of experimental animals].

The authors observed the dependence of morphometric indicators of myelinated nerve fibers on the age of experimental animals. They performed a morphometric analysis of myelinated nerve fibers, namely nervous peroneus communis in male adult white rats of 17, 21, 25 and 31 weeks of age. They discovered that the values of individual morphometric indicators of axons of myelinated nerve fibers (axon perimeter, axon circular diameter, axon area, circular axon area) and their distribution vary in dependence on age of experimental animals. The authors emphasize that observation of experimental alterations of morphometric indicators of myelinated nerve fiber axons requires a comparison of findings in groups of animals with those in control groups of animals of the same age. (Tab. 2, Fig. 4, Ref. 28.)

Aging↗

PubMed1993

[Dynamics of digoxin-like immunoactivity during the oral glucose tolerance test in pregnant women].

The changes of serum digoxin-like immunoactivity (DLIA) during 75g oral glucose tolerance test (OGTT), were investigated in 25 pregnant women with various glucose tolerance. 13 women had a normal glucose tolerance (NGT), 12 women had an impaired glucose tolerance (IGT) or gestational diabetes mellitus (GDM). Test was performed after 25 week of pregnancy. The results were compared with 9 nonpregnant healthy volunteers (NHV). After an oral glucose challenge, there was observed a significant decrease in serum DLIA (p < 0.01 in 1st hour), in both groups of the pregnant women. In the group of NHV these findings were not found. Our findings suggest a possible relationships between DLIA and glucose tolerance in pregnant women. However, it needs further investigation. (Tab. 1, Fig. 1, Ref. 24.)

Adult↗

PubMed1992

[Endogenous digitalis-like substance in relation to glycemia and insulinemia].

The digitalis-like substance (DLS), insulin resistance, and hyperglycemia are ascribed important roles in the pathogenesis of essential hypertension. The relationship between DLS and glycemia (insulinemia) was investigated in the present study. The levels of glycemia, insulinemia and DLS were measured during oral glucose load in a group of 18 subjects with various blood pressure values. Fasting levels of glycemia and insulinemia were in each subject within the physiological range and no correlation was found to exist between the fasting levels of DLS and glycemia (insulinemia). One hour after oral glucose load the increase of glycemia and insulinemia was significantly higher in the group of subjects with SBP > 140 and/or DBP > 90 mmHg than in normotensive subjects (p < 0.001). The increase in glycemia (insulinemia) was followed by a decrease of DLS. This contrary trend could be expressed as a significant inverse correlation between the change in plasma DLS and the change in glycemia (r = -0.660 p = 0.0039), and also between the change in plasma DLS and the change insulinemia (r = -0.687 p = 0.0023). These findings are assumed to suggest certain mechanisms involved in the pathophysiology of essential hypertension. (Tab. 3, Fig. 2, Ref. 20.)

Adult↗

PubMed1989

[Review of the morphological changes in peripheral nerves in experimental diabetes mellitus].

A survey of morphological changes of myelinated nerve fibers of peripheral nerves recorded in experimental streptozotocin induced diabetes mellitus in rats is presented. Causes of discordant interpretations of findings are considered and pathogenetic mechanisms involved in morphological changes of myelinated nerve fibers of peripheral nerves observed in this model of diabetes mellitus are discussed. (Ref. 41.)

Animals↗

PubMed1988