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Biomedical subjects

M O Iankovskaia

Publications and source records attributed to M O Iankovskaia.

At least 19 recordsLinked to original sources
PubMed1994

[Hemodynamics and anaerobic glycolysis during the head-down tilt test in myocarditis patients].

The analysis is presented of the changes observed in hemodynamics and anaerobic metabolism in myocarditis patients given increasing preload. It is shown that the antiorthostatic test can specify substantial deposition of blood in the lesser or greater circulation. Patients with congestive cardiac insufficiency demonstrate more frequently increased lactate levels in the blood of the coronary sinus and reduced myocardial extraction of lactate.

Adolescent↗
PubMed1993

[Disorders of the central and intrapulmonary hemodynamics as an index of the degree of severity in myocarditis patients].

Central and intrapulmonary hemodynamic parameters were examined by direct and indirect methods in 46 patients with myocarditis (25 females and 21 males), which revealed diminished myocardial contractility, which was followed by a regular and significant pulmonary blood pressure and a reduction in the elastic properties of the pulmonary-arteriolar bed. Central and intrapulmonary hemodynamic changes are mostly associated with the development of hypodynamia and more rarely with that of the phase hemodynamic syndrome and more rarely with the volume overloading syndrome.

Adolescent↗
PubMed1991

[Clinico-morphological characteristics of pericardial mesothelioma].

The authors describe clinical and morphological features of a rare tumor, pericardial mesothelioma. Their findings lead them to a conclusion that the epithelioid cell form (tubular and papillary variants) is the most incident histologic form of this tumor. They emphasize that life-time diagnosis of pericardial mesothelioma is of paramount importance because rational chemotherapy permits prolongation of the patient's survival.

Adult↗
PubMed1991

[Clinico-morphological characteristics of dilated cardiomyopathy].

The paper presents the results of a clinicomorphological study of 50 patients with dilated cardiomyopathy. ECG, echocardiography, x-ray revealed atrial fibrillation, parasystole, extrasystole, impairment of intraventricular conduction, symptoms of a focal cicatricial myocardial lesion, high end-systolic and end-diastolic volumes, reduced ejection fraction, marked axial dilatation of the heart. Morphologic evaluation showed diffuse and diffuse microfocal cardiosclerosis, combination of sites of hypertrophic myocardiocytes with dystrophic foci, atrophy, sclerosis. Morphological evidence is available for arrhythmic, cardiomegalic, aneurysmic, infarction-like and pseudovalvular dilated cardiomyopathy.

Adult↗
PubMed1986

[Diagnostic significance of indices of kininogenesis in infectious-allergic myocarditis].

Three patterns of kininogenetic changes: enhanced (50% of patients), depressed (40%) and qualitatively-different (10%) kininogenesis, were identified through 3 measurements of blood kallikrein-kinin (BKK) activity by kininogenase techniques in patients with infectious allergic myocarditis and myocarditic cardiosclerosis. The intensity of individual phases of kininogenesis is conditioned by the activity of total plasma kallikrein, its conformation and the level of kallikrein inhibitors. During the activated kininogenesis phase, a direct relation can be seen between changes in the activity of the above-mentioned parameters and clinical severity of the disease. The measurement of total kallikrein activity, kaolin adsorption of this enzyme, and kallikrein inhibitors may be useful as an additional diagnostic test. The pattern of changes in BKK activity parameters may be indicative of persisting or progressing myocardial inflammatory allergic process in patients with myocarditic cardiosclerosis. The treatment for myocarditis with conventional anti-inflammatory agents, leaving out the drugs controlling kininogenetic changes, fails to produce complete recovery and the normalization of BKK activity.

Adult↗
PubMed1983

[Comparative diagnostic value of laboratory tests in infectious allergic myocarditis].

A comparative assessment of a series of laboratory tests has been made in 206 patients with infectious-allergic myocarditis. Routine laboratory parameters were shown to be of little informative value. Neutrophil alkaline phosphatase activity, the index of neutrophil damage with respect to soluble cardiac antigen, basophil and eosinophil degranulation, and absolute blood basophil and eosinophil quantity were found to be the most meaningful criteria for the assessment of the activity of inflammatory and allergic processes in patients with infectious-allergic myocarditis.

Acid Phosphatase↗