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Biomedical subjects

M Noya

Publications and source records attributed to M Noya.

At least 73 records · Page 4Linked to original sources
PubMed1991

Bone anomalies in myotonic dystrophy.

Sixteen patients with myotonic dystrophy underwent CT examination of the skull, and measurement of bone mineral density at lumbar spine and hip by dual-photon absortiometry. The results were compared with those of 20 normal subjects of similar age and sex distribution. Hyperostosis of the calvarium, and increased bone mineral density at lumbar vertebrae were observed. One case showed basal ganglia calcification associated with hyperparathyroidism secondary to deficiency of vitamin D. In the other 15 patients, studies of calcium metabolism were normal. There results suggest the existence of generalized hyperostotic potential in patients with myotonic dystrophy.

Adolescent↗
PubMed1991

[Platelets and migraine. Correlation between biochemical markers of platelet aggregation and serotonin].

The correlation between the biochemical markers of platelet activation and serotonin in migraine was investigated. The beta-thromboglobulin (beta-TG), platelet factor 4 (PF-4) and serotonin levels in 105 patients with migraine were measured. The results confirmed an increase in beta-TG and PF4 levels and a reduction in serotonin levels during the migraine attacks. However, we did not find a significant correlation between these fluctuations. These findings suggest the existence of extraplatelet mechanism in the pathophysiology of migraine.

Adolescent↗
PubMed1990

[Hormonal profile and changes in platelet aggregation in menstrual migraine].

We evaluated the hormonal profile and the platelet function in a group of 20 patients with menstrual migraine and a control group of 10 healthy women. Plasma levels of estradiol, progesterone, FSH and LH, as well as betathromboglobulin, platelet factor 4 and platelet serotonin were measured in different phases of the menstrual cycle. The hormonal profile did not show significant differences between both groups. The patients with menstrual migraine had higher BTG, FP4 and serotonin levels in the premenstrual phase than the control group. The results of this study show that in premenstrual migraine a platelet hyperagregation develops during the premenstrual phase. This abnormality is not directly correlated with the hormonal fluctuations observed during the menstrual cycle.

Adult↗
PubMed1990

[Platelet function in tension headache].

The possibility of abnormal platelet function in patients with tension headache was evaluated with serial plasmatic measurements of serotonin, beta-thromboglobulin and platelet factor 4. In 40 patients with tension headache we found increased serotonin, thromboglobulin and platelet factor 4 levels during the painful phases as compared with the asymptomatic phases. These data might indicate that an increased platelet aggregation plays some role in the pathogenesis of tension headache.

Adult↗
PubMed1989

[Magnetic resonance in the evaluation of neurologic complications of cervical spondylosis].

The evaluation of the neurological complications of cervical spondylosis frequently requires contrast myelography. Magnetic resonance (MR) scan would appear as a good alternative approach. We report the MR findings in 12 patients with symptoms and/or signs of spinal cord and radicular disease associated with cervical spondylosis, and we compare them with the conventional studies, including CT and CT assisted myelography. The MR image, weighted in T1, permitted to visualize the compressed spinal cord in the sagittal planes in 4 cases, with enhanced spinal cord signal in 2 of them. In a patient with herniated C5-C6 disk, the sagittal sections directly demonstrated the herniated material in the spinal canal, displacing and compressing the spinal cord. The sequences weighted in T2 demonstrated the degree of stenosis of the cervical canal caused by extradural compression. In these images, the diminished signal of the nucleus pulposus was correlated with degeneration of intervertebral disks. MR was more sensitive than the other studies to detect discal degeneration and herniation, stenosis of the spinal canal, compression of the subarachnoidal space and spinal cord injury.

Aged↗