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Biomedical subjects

M Neubauer

Publications and source records attributed to M Neubauer.

At least 91 records · Page 5Linked to original sources
PubMed1976

Hypophyseal function in the operative and postoperative phases after removal of pituitary tumours.

In 47 patients with various pituitary tumours plasma cortisol, LH, FSH, prolactin, and GH were measured by radioimmunoassays to investigate anterior pituitary function. In 14 subjects LH--RH and TRH stimulation tests were performed to assess pituitary reserve before, during, and after surgical therapy. The mean cortisol levels were raised during and after the operative procedures until the 14th postoperative days. In patients with functionless tumours the other hormone concentrations remained nearly unchanged and in the normal ranges. After the removal of the tumour a rapid decrease in hormone levels, as might be expected, was rare, with the exception of the GH and prolactin levels in patients with hypersecretion. The postoperative stimulation tests showed a maintained secretory pituitary reserve due to active tissue left behind after operative removal of the tumour.

Adenoma↗
PubMed1975

[Androgens in the plasma of women with hirsutism (author's transl)].

109 women with hirsutism were investigated (102 with idiopathic hirsutism, four with Stein-Leventhal syndrome, one each with adrenal adenoma, adrenal carcinoma and hilus-cell tumour). Levels of testosterone, dihydrotestosterone, androstenediol and dehydroepiandrosterone were measured, usually in the course of a combined adrenal-ovarian stimulation-suppression test. Measuring several plasma androgens made it possible to distinguish idiopathic hirsutism from other endocrine diseases with hirsutism. Mean plasma testosterone level in idiopathic hirsutism was not significantly different from that in healthy women. Elevated testosterone and(or) dihydrotestosterone levels were found in only 22 of 102 women. There was a marked increase in plasma testosterone after HCG injection in the patient with Stein-Leventhal syndrome. Androstenediol and dehydroepiandrosterone were both important in the diagnosis of autonomous adrenal steroid secretion.

Adenoma↗