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Biomedical subjects

M Naughton

Publications and source records attributed to M Naughton.

36 records · Page 2Linked to original sources

Chronic eosinophilic pneumonia. A long-term follow-up of 12 patients.

Chronic eosinophilic pneumonia (CEP) is a rare disorder of unknown etiology characterized by striking systemic and pulmonary manifestations such as fever, weight loss, blood eosinophilia, characteristic fluffy peripheral opacities on chest radiograph, and a prompt response to corticosteroid therapy. While the initial phase has been well documented, there is very limited information concerning the long-term natural history and treated course of this condition. We report the clinical and laboratory findings together with the long-term follow-up data on 12 patients with classic CEP who were followed up for a mean of 10.2 years (range, 4 to 13 years). The most striking feature of the long-term follow-up was the occurrence of relapses of CEP (often on multiple occasions) when corticosteroid therapy was discontinued or the dose was tapered. In those nine patients in whom steroid withdrawal was commenced, there was a clinical, hematologic, and radiologic relapse in seven (58 percent). However, prompt reinstitution of therapy led to a rapid resolution of symptoms. By contrast, two patients (17 percent) showed no evidence of relapse when steroid therapy was discontinued. A further three patients (25 percent) are maintained on a regimen of low-dose steroid therapy with no episodes of relapse. Reassuringly, all 12 patients are well at the end of a long period of follow-up. These data suggest that the long-term prognosis for patients with CEP is excellent but the majority will require long-term low-dose oral corticosteroid therapy in order to prevent relapse.

Adolescent↗

Sleep related breathing disorders.

Sleep disorders encompass a broad group of conditions. In this article the sleep related breathing disorders are considered from the initial presentation through diagnosis and investigations to management.

Humans↗

Pneumomediastinum after a transbronchial biopsy.

A pneumomediastinum occurred after a transbronchial biopsy in a woman with pulmonary fibrosis and was confirmed by computed tomography. Although pneumomediastinum has a pathogenesis similar to that of pneumothorax it has not been reported after transbronchial biopsy.

Biopsy↗

Prevalence and predictors of smokeless tobacco use: Iowa's program against smoking.

Data from surveys of adolescents were analyzed so that we could determine the prevalence of smokeless tobacco use and identify and compare the concurrent correlates of its use and cigarette smoking. Panel data from seventh through eleventh and eighth through twelfth graders between 1980 and 1984 and cross-sectional data from seventh graders in 1980 and 1985 suggest that boys are more likely to use SLT than are girls and that the boys' use has increased with age and over time. Concurrent correlates of seventh-grade boys' and girls' SLT use and cigarette smoking were identified with discriminant analyses. Predictors of smokeless tobacco use were compared with those of weekly smoking for boys and girls separately. Predictors of use by boys were also compared with those by girls. Trying alcohol and the other form of tobacco were the only predictors that related to the use of either form by boys and girls. Differences among other predictors were noted and their implications for prevention are discussed.

Adolescent↗

Preparing nonretarded young persons to meet mentally retarded adults.

A representative sample of 420, 15- and 16-year-old students in Dublin city participated in a short educational program designed to introduce them to mentally retarded adults. The main feature was a carefully, structured contact session with retarded peers held in the students' school. Various control procedures ascertained that the program had been effective at increasing the students' confidence at meeting retarded people. Moreover, the majority of students voluntarily chose to visit a local mental retardation center, and a proportion of them maintained regular contacts. We argued that students need to be given explicit guidance on how to interact with retarded peers.

Adolescent↗

A national survey of young people's perceptions of mental handicap.

Over 1300, 15 and 16-year-old students throughout Ireland, completed a range of questionnaires which covered their past contact with mentally handicapped adults, their perceptions of them, their views on integration within society and their knowledge about the causes of this disability. It was found that only one quarter of the students had ever interacted with a mentally handicapped adult and nearly half of them had never been in their company. There were marked differences between these subgroups in their perceptions of, and attitudes to, mentally handicapped people. Equally striking were the differences between male and female students, although the effects of social background, city versus country and socio-economic status, were less pronounced. The implications for school-based, educational programmes on disability are discussed and areas for further research are highlighted.

Adolescent↗

Changing young people's perceptions of mentally handicapped adults.

A representative sample of 420, 15- and 16-year old students, participated in a short educational programme about mental handicap; the main feature of which was a well-structured contact session with a group of mentally handicapped adults. This lasted 40 min and took place in the students' school. Various control procedures ascertained that the programme was effective at increasing their confidence in meeting mentally handicapped people and in their knowledge of the causes of mental handicap. Moreover the majority of students voluntarily visited a local mental handicap centre and a proportion maintained regular contact. These findings were replicated in a second study involving a further 368 students but this time the programme was presented by teachers and/or personnel from a local mental handicap service. The salient features of the contact sessions are discussed and directions for future research noted, particularly explicit guidance for adolescents on interacting with atypical peers.

Adolescent↗

Development of Amsacta moorei entomopoxvirus in ovarian and hemocyte cultures from Estigmene acrea larvae.

Primary ovarian and hemocyte tissue cultures prepared from Estigmene acrea larvae were infected with Amsacta moorei entomopoxvirus. Infection of cultures was achieved with either purified virus or virus-containing culture medium from infected cultures. Virus replication and formation of virus-containing inclusions (VCI) were similar to that normally observed in vivo except that fewer virions appeared to be occluded in VCI.

Blood Cells↗

Developing nursing's future role: a challenge for the millennium: 1.

Over the past decade health care in general and nursing in particular have experienced a period of unprecedented change resulting from a variety of factors including demography, advances in technology and the introduction of differing service delivery systems. For nursing this has created a number of tensions, especially between professional aspirations and the demands of a new managerial culture. Many nurses have found themselves torn between the push towards the ideal of individualized holistic care and the reality of resource constrained environments. The new White Paper 'The New NHS: Modern, Dependable' (Secretary of State for Health, 1997) heralds a move away from the 'short termism' of the internal market towards a partnership model of integrated care. It also reaffirms the Government's commitment to further develop the role of the nurse. This article, the first of two, considers the challenges nurses face in responding to a managerial agenda while simultaneously maintaining the development of the nursing profession. The opportunities afforded by the recent White Paper are identified and the need to address a number of current tensions are highlighted. Developments at the Northern General Hospital in Sheffield are briefly described, with the results of a major survey being presented in the second article.

Delivery of Health Care, Integrated↗

Developing nursing's future role. 2: Nurses' job satisfaction and morale.

This, the second of two articles, presents the results of a recent survey of nurses' job satisfaction and morale undertaken at the Northern General Hospital NHS Trust, Sheffield. The survey was conducted in order to provide a benchmark against which to gauge progress towards creating a work environment in which nurses are able to exercise maximum autonomy within a supportive and enabling culture. The results mirror recent national reports which highlight the increasing tension between workload pressures and the desire to provide holistic patient care. A number of factors were identified which suggest the need for remedial action across a range of fronts. Such factors are briefly described, together with the action taken to date to address the issues raised.

England↗

Jobshares for experienced nurses.

Performance audit from a clinical perspective has been widely accepted. Within Harrogate Health Care NHS Trust, a review of hours worked on day and night duty, coupled with a review of skill mix in one area, led to the successful introduction of a jobshare scheme for experienced nurses.

Humans↗