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Biomedical subjects

M Nasu

Publications and source records attributed to M Nasu.

At least 361 records · Page 20Linked to original sources
PubMed1984

Gastric plasmacytoma and multisystem autoimmune disease.

A 54-year-old women with solitary gastric plasmacytoma, Ig M and kappa-light chain type, associated with multisystem autoimmune disease is described. The gastric plasmacytoma developed seven years after the diagnosis of Hashimoto's thyroiditis, primary biliary cirrhosis and Sjögren's syndrome. We speculate that this plasmacytoma developed in association with an immunodeficient and/or immunosuppressed state resulting from multisystem autoimmune disease and therapy.

Autoimmune Diseases↗
PubMed1984

Pedunculated hepatoma--report of two cases and review of the literature.

Although pedunculated hepatoma has received little attention in the United States and Europe, in Japan more than forty cases have been reported, probably owing to the relatively high frequency of hepatoma. Formerly preoperative diagnosis was difficult in the early period. Recently it can be made by ultrasound, computed tomography and angiography, however, the choice of operative procedure is not uniform. In some cases good results were obtained by only tumor excision or partial hepatic resection, whereas other cases presented undergoing more extended resection show a poorer course. In the present case 1, intrahepatic recurrence was recognized three months after surgery in spite of relatively early diagnosis. Reviewing the literature, it appears that the degree of invasion at the pedicle is mainly related to prognosis. If invasive, segmentectomy or lobectomy is necessary and postoperative adjuvant therapy is needed.

Carcinoma, Hepatocellular↗
PubMed1984

Cephalosporin-resistance in the Bacteroides fragilis group and the effect of clavulanic acid.

Thirty-five beta-lactam-resistant isolates of the Bacteroides fragilis group were examined for the susceptibility to eight cephalosporins, alone, and in combination with a subinhibitory concentration of the beta-lactamase inhibitor, clavulanic acid. The majority of strains tested became fully susceptible to cephaloridine, cefotaxime and ceftriaxone in the presence of clavulinic acid whereas the effect of the inhibitor on the susceptibility to compounds such as cefsulodin and ceftazidime and to a lesser extent cefoperazone varied according to species. Bact. fragilis strains almost invariably showed substantial reductions in MICs whereas those of other species, especially Bact. thetaiotaomicron, were influenced to a lesser extent. Susceptibility to cefoxitin was unaffected by the inhibitor but a few strains with high level resistance to latamoxef (moxalactam) became susceptible in the presence of clavulanic acid. All strains were found to produce beta-lactamase as determined by the nitrocefin test and these were characterized by isoelectric focusing.

Bacteroides fragilis↗
PubMed1984

Occurrence of galactosamine-6-phosphate as a constituent of Bacillus megaterium spore coat.

Galactosamine-6-phosphate was identified as a component of the coat of the Bacillus megaterium QM B1551 spore. It was one of the main constituents of the outermost layer of the spore coat, but it was absent from the other integuments including the cortex. These findings suggest that galactosamine-6-phosphate comprises the phosphorus-containing skeleton structure of the spore coat.

Bacillus megaterium↗
PubMed1984

Ameloblastic fibrosarcoma: an ultrastructural study of the mesenchymal component.

The mesenchymal components of tumors from 2 patients with ameloblastic fibrosarcoma were studied ultrastructurally. The mesenchymal components consisted predominantly of fibroblastic cells with a few histiocytic or fibrohistiocytic cells and myofibroblastic cells. In addition, a very small number of undifferentiated mesenchymal cells were found. We speculate that the mesenchymal components in this tumor may be derived from the undifferentiated mesenchymal cells.

Adult↗
PubMed1984

Ultrastructural and histochemical studies of granular-cell ameloblastoma.

Four cases of granular-cell ameloblastoma were studied by light and electron microscopy, histochemistry and electron enzyme histochemistry. Microscopically, granular cells commonly occurred in a follicular pattern, but, in one case, they were in a plexiform pattern. The high activity of acid phosphatase and electron microscopic features revealed that the cytoplasmic granularity was ascribed to the high content of lysosomes. It was speculated that granular-cell ameloblastoma occurs due to the altered dysfunction of tumor cells, and the age factor is related to the pathogenesis of this tumor.

Acid Phosphatase↗