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Biomedical subjects

M Nadarajah

Publications and source records attributed to M Nadarajah.

26 records · Page 2Linked to original sources

Isolation of Legionella pneumophila from hospital cooling towers.

Water from twenty cooling towers from three major hospitals (A, B, C) were screened for the presence of Legionella pneumophila. Three of the water specimens were found to be positive for the organism. Serogroup 1 was isolated from the two cooling towers in Hospital A, while serogroup 4 was isolated from one of the cooling towers in Hospital B, this being the first time L. pneumophila has been isolated in Singapore.

Cross Infection↗

Counterimmunoelectrophoresis in the rapid diagnosis of bacterial meningitis.

Cerebrospinal fluid from patients with clinically diagnosed meningitis was tested for meningococcal, pneumococcal, streptococcal Group B and Haemophilus influenzae antigens by counterimmunoelectrophoresis. Antigens were rapidly identified and the results compared favourably with that of bacteriological culture. In the case of pneumococcal meningitis counterimmunoelectrophoresis proved to be more sensitive than culture. The procedure was shown to be sensitive, specific, rapid and easily performed.

Acute Disease↗

Epidemiological features of an outbreak of gastroenteritis/cholera in Katsina, Northern Nigeria.

In April 1982, Katsina, in Northern Nigeria, was affected by an outbreak of gastroenteritis associated with Vibrio cholerae serotype 'Ogawa' and 662 patients were admitted to the Katsina General Hospital during a 16-week period. The outbreak affected all ages and both sexes and all parts of the town and its immediate surroundings except the Government Residential Area (GRA). The overall case fatality rate was 7.7%. Male specific case fatality and female specific case fatality rates were 9.7 and 6.2% respectively. 'Adults' and those in the 11-20 and 21-30 age groups accounted for most of the cases. The epidemic curve was of a propagated and protracted nature. About 51.7% of all the patients spent between 2 and 5 days in the hospital. A similar pattern was observed for all age groups regardless of sex. Cholera vibrio 'Ogawa', Shigella spp., Salmonella spp., Proteus spp. and Escherichia coli were isolated from 16 patients. All well-water samples obtained from the compounds of the cases were contaminated with MPN/100 ml index ranging from 540 to greater than 2400. All samples were positive for faecal coliforms. Salmonella spp., Shigella spp., Proteus spp. and non-O, group 1 (non-O 1) V. cholerae were isolated. Water sellers probably facilitated the spread of the outbreak.

Adolescent↗

Bacterial meningitis--a five year review 1975--1979.

In a five year period 142 cases of bacterial meningitis were reported, of which 50 per cent were children under the age of four years and a third of the children were neonates. The commonest organism isolated was Streptococcus pneumoniae, there being 28 cases. The incidence of Klebsiella organism causing meningitis has been on the increase, and 20 cases were reported within this period. There has been a change in pattern of neonatal meningitis, with group B streptococcal infection predominating over the gram negatives.

Bacterial Infections↗