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Biomedical subjects

M Myquel

Publications and source records attributed to M Myquel.

9 recordsLinked to original sources
PubMed1981

[Neurological tolerance of lithium-psychotropic drugs association (author's transl)].

The authors have studied the neurological tolerance from the combination of lithium-psychotropic drugs from 265 associated cures carried out on 132 patients between 1971 and 1978. The risk of neurological inability to assimilate is not greater when haldol is combined with lithium by comparison with other combinations where it is not included. Only the presence of cerebral organicity presents a risk factor. The 117 associated cures were preceded by preliminary treatments during which either the lithium or the psychotropic drugs were used to the same extent during the treatment. This series seems to allow on one hand to demonstrate that the incidence of neurological signs is multiplied by two by the combination, on the other hand to note that the intensity of the neurotoxic effects increases.

Adult↗
PubMedDate not supplied

[Clinical significance of the erythro-plasmatic ratio of lithium (author's transl)].

Six hundred erythrocyte-plasma lithium ratios have been gathered from 67 patients presenting affective disorders. Ratios values in relapse period are not altered regarding those in remission phase as between periods with neuroleptic associations and those without. Ratios values are not noticeably modified by personality, sex and the evolution of affective disorders. But lithium preventive action is essentially found in patients with high erythrocyte-plasma.

Antipsychotic Agents↗
PubMedDate not supplied

[Two-dimensional immuno-electrophoresis of cephalospinal fluid proteins wih a study of the IgG/albumin ratio in psychiatry (author's transl)].

The purpose of this study (about 187 adult psychiatric patients) is to investigate correlations between "organic brain syndrome" (vascular or abiotrophic) and values of CSF proteins (technique of two-dimensional immunoelectrophoresis). The authors show positive correlations between 'vascular' brain syndrome and increase of one alpha 2 globulin, between 'abiotrophic' brain syndrome and decrease in all globulins, the importance of brain damage and increase of IgG/albumin ratio.

Adult↗