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Biomedical subjects

M Mozes

Publications and source records attributed to M Mozes.

113 records · Page 7Linked to original sources
PubMedDate not supplied

Peripheral nerve section as palliation for severe ischemic foot pain.

Multisensory peripheral nerve divisions were performed in 17 elderly patients with severe ischemia, forefoot pain and non-healing lesions or localised gangrene. They were unsuitable for a vascular reconstructive operation, or for localised foot amputation. The mean age of the patients was 73 years; 13 were males and 10 had diabetes mellitus. All were faced with a major amputation. Considerable pain relief was achieved in all patients but only five patients retained a functional lower extremity for more than 6 months. Of these five one was a diabetic and four were non diabetic. Peripheral nerve section is a useful procedure, but should be applied very selectively and only rarely in diabetic patients.

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PubMedDate not supplied

Mineral and endocrine metabolism during fracture healing in dogs.

The blood levels of parathormone (PTH), calcitonin (CT), vitamin D metabolites, calcium, phosphate, magnesium and alkaline phosphatase (AKP) were determined in 13 young dogs with experimental fractures of long bones. The parameters were measured before the fracture and during healing until the appearance of an early callus. Serum Ca levels were significantly reduced immediately after the fracture (10.95 +/- 0.30 mg/dl to 10.25 +/- 0.25 mg/dl; p less than 0.05). Significant rises in serum levels of PTH (0.99 +/- 0.10 ng/ml to 1.57 +/- 0.22 ng/ml; p less than 0.01); CT (0.14 +/- 0.01 ng/ml to 0.18 +/- 0.01 ng/ml; p less than 0.05); 24,25-dihydroxyvitamin D (13 +/- 2 ng/ml to 19 +/- 3 ng/ml; p less than 0.01) and AKP (153 +/- 24 U/l to 211 +/- 26 U/l; p less than 0.01) were noted during fracture repair. A reduction in serum levels of 25-hydroxyvitamin D (22 +/- 2 ng/ml to 15 +/- 1 ng/ml; p less than 0.001) was noted at the same time. The parameters returned or tended to return to normal levels during callus development. The data demonstrate the changes in levels of Ca-regulating hormones in response to bone injury. This suggests that CT and 24,25-dihydroxyvitamin D (24,25-(OH)2-D) can be associated with the process of callus formation.

Alkaline Phosphatase↗