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Biomedical subjects

M Monti

Publications and source records attributed to M Monti.

At least 289 records · Page 16Linked to original sources
PubMed1979

[Cutaneous mycobacteriosis of aquaria. A disease transmitted from fish to man].

The Authors refer about one case of cutaneous infection from Mycobacterium marinum transmitted to man from tropical fishes of a fish tank. The Authors describe the lesions produced by mycobacterium in man and in fish, as well as the relevant hystological findings and the microbiological enquiries carried out for isolation and typing. The possibility of direct transmission of a tubercular infection from fish to man has been demonstrated. The Authors think it to be useful a careful sanitary control on the ichthyc fauna destined to domestic fish tanks.

Animals↗
PubMed1979

[Considerations on a series of malaria cases].

Stress is laid on the seriousness of malaria and the causes of its unusual clinical pictures. Results obtained in the evaluation of G-6-PD, PK, intracellular K and globular resistance, in addition to other parameters, suggest (as pointed out in the literature) that altered cell metabolism may be the primary cause of haemolysis. Attention is also drawn to the lengthy persistance of gametes after gametocidal management in some patients, and the risks that this involves.

Anemia↗
PubMed1979

Heat production by lymphocytes in chronic lymphocytic leukaemia.

Using microcalorimeters of the thermopile conduction type heat production was measured in lymphocytes from peripheral blood in 8 normals and 10 patients with chronic lymphocytic leukaemia (CLL). The heat production per CLL lymphocyte was lower (1.8 pW/cell) than that found in normal lymphocytes (2.6 pW/cell). Due to the high numbers of lymphocytes in the peripheral blood the estimated heat production of the intravascular lymphocyte pool in CLL was considerably higher than in normals. Since the circulating lymphocytes constitute a minute fraction of the total lymphoid mass in CLL it is suggested that the accumulation of metabolically active lymphocytes in blood and tissues may explain the common clinical signs of hypermetabolism in this disease. The results also indicate that calorimetry may be a useful technique for metabolic studies in suspensions of malignant cells.

Body Temperature Regulation↗
PubMed1979

[Habitual physical activity and responsibility at work as risk factors of fatal coronary heart disease (author's transl)].

Mortality in 5 and 10 years for all causes in over 172,000 men classified for habitual physical activity at work was not substancially different between subjects classifed as sedentary, moderate and heavy workers. Mortality for coronary heart disease (CHD), for the same length of observation was statistically higher in sedentary and moderate than in heavy workers (ratio 1.7/1). Bivariate analysis considering both physical activity and responsibility at work, limited to 99,000 men aged 40-59 at entry for a period of 5 years having as end-point CHD, indicated that mortality is higher for higher levels of responsability. Partial correlation coefficients between physical activity and working responsibility on one side, and mortality for CHD on the other showed significant levels (-0.72 and 0.71 respectively) when considering eight combination of different activity and responsibility levels.

Adult↗
PubMed1978

[The gamma-glutamyl transpeptidase (GGTP) as an index for the diagnosis of chronic alcoholic cholestatic hepatitis (author's transl)].

The GGTP is an enzyme localized, in the liver cell, inside microsome. At beginning the use of the GGTP was introduced for the diagnosis of chronic hepatitis; after it was noted as this was steady increased in the cholestasis and in the alcoholism. We have, hence, wanted to experiment if the changing of the level of the GGTP allowed to us a diagnosis of chronic alcoholic hepatitis. Our research is based on seventy-five patients with several liver diseases. It has been noted as the highest levels of the GGTP have appeared in cases of chronic alcoholic hepatitis with signs, histologicals and biochemicals, o cholestasis. In fact we have, on overage, levels of 955 mU/ml in the chronic alcoholic hepatitis with signs of cholestasis and of 135 mU/ml in that without it. In conclusion the GGTP is a good index for the diagnosis of chronic alcoholic cholestatic hepatitis.

Cholestasis↗
PubMed1977

[The role of reduction of the heart rate in the favorable effect of the beta blockers on myocardial ischemia due to isoprenalin in patients with angina pectoris].

In the patient suffering from angina, the protective effect of oxprenolol in the isoprenaline test is demonstrated by the reduction of disappearance of ischemic-type electrocardiographic alterations and of angina and rhythm disturbances. In our study, these results were obtained in spite of neutralization of the negative chronotropic effect of the beta-blocker through the use of an endo-auricular pacemaker. This points indirectly to the role played by the contractile state of the myocard in catecholamine-induced modifications of the oxygen intake of cardiac muscle.

Adult↗
PubMed1977

Microcalorimetric measurements of heat production in erythrocytes of patients with chronic uraemia.

The metabolic activity in the erythrocytes of 12 patients with chronic uraemia was studied by a microcalorimetric method. When the pentose phosphate pathway activity of erythrocytes was stimulated with 10(-4) M methylene blue (MB), significantly higher levels of heat effect were found in the group of uraemic patients than in a group of healthy subjects. The difference between the 2 groups was higher in plasma (p less than 0.005) than in phosphate buffer suspensions (p less than 0.05). The ratio between the mean values for the 2 groups was 1.18 both in plasma and in phosphate-buffer. Also for unstimulated cells the heat effect values were higher in the group of uraemic patients than in the control group. The ratio was 1.21 (p less than 0.005) and 1.14 (p less than 0.05) for plasma and buffer suspensions, respectively. The present results are in disagreement with previous reports, according to which haemolytic anaemia among uraemic patients is due to decreased erythrocyte aerobic metabolism.

Anemia, Hemolytic↗