Biomedical subjects
M Moller
Publications and source records attributed to M Moller.
Nervous connections between the brain and the pineal gland in the cat (Felis catus) and the monkey (Cercopithecus aethiops).
Silver-impregnated series of cat and monkey (Cercopithecus aethiops) brains were studied in an attempt to demonstrate the existence of nervous connections between the brain and the pineal gland via the pineal stalk (central pineal connections). The presence of such connections between both the pineal gland and the habenular area, and between the pineal gland and the posterior commissure was verified in this study. A well defined median nerve tract between the pineal gland and the posterior commissure is described.
Presence of a pineal nerve in sheep and rabbit fetuses.
The presence of a nerve located just caudal to the pineal gland in the midsagittal plane is demonstrated in sheep and rabbit fetuses. This nerve lies freely in the subarachnoid space and extends from the pineal gland to a region of the CNS located dorsal to the rostralmost part of the subcommissural organ (SCO). In rabbit fetuses the nerve is obsered on days 23 and 24 of gestation; we suggest that it is an ontogenetic equivalent to the pineal nerve of anuran amphibians. The developmental fate of the mammalian fetal pineal nerve is dicussed.
Lack of effect of portacaval shunt on ornithine decarboxylase activity in regenerating rat liver.
The influence of the end to side portacaval shunt on the level of activity of the enzyme ornithine decarboxylase following partial hepatectomy was investigated. A sharp rise in the enzyme level was found in both the shunted animals and in the normal controls. The chronology of the increase in enzymic activity was somewhat altered in the portacaval shunted animals, but both groups had similar peak values. The rate of cell division was also found to be unaffected. This report finds no evidence of support for the reported inhibition by the portacaval shunt of the increase in ornithine decarboxylase following partial hepatectomy.
Dendrodendritic gap junctions: a developmental approach.
Dendrodendritic gap junctions have been identified in the periaqueductal gray substance of adult rabbits and in the visual cortex of sheep fetuses. The introduction of Alcian blue as a marker substance facilitated the positive identification of gap junctions. Dendrodendritic contacts in the human fetal neocortex have been examined in freeze-cleaved specimens. The contacts are identified as gap junctions by their freeze-fracture appearance. Features of the developing dendrodendritic gap junctions are described. The possible significance of these contacts is discussed, and it is suggested that they provide electrotonic coupling of neurons belonging to the same columnar organization. In addition it is suggested that the dendrodendritic gap junctions of fetal neocortex participate in cell differentiation and morphogenesis of the cerebral wall.
[Merckognost-ureastix for determination of carbamide in serum and whole blood].
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The ultrastructure of the human fetal pineal gland. I. Cell types and blood vessels.
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Concordance between morphological and biochemical estimates of fluid spaces in rat brain cortex slices.
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The ultrastructure of the carotid body in chronically hypoxic rabbits.
1. The ultrastructure of the carotid body in the rabbit has been examined by electron microscopy.2. A comparison was made between the ultrastructure of the carotid bodies in sea level rabbits, in rabbits which had been exposed to hypoxia equivalent to an altitude of 6000 m for 7 days and in rabbits which always had lived at an altitude of 4000-4300 m.3. We could not detect any difference in the ultrastructure between the two groups of hypoxic rabbits.4. When the hypoxic rabbits were compared with sea level rabbits there was a marked increase in the number of dense cored vesicles and mitochondria in the type I cells in the hypoxic rabbits. The Golgi region also appeared to be enlarged in the type I cells in the hypoxic rabbits.5. The finding suggests that in the rabbit the production of amines, probably dopamine, within the type I cells is increased during prolonged hypoxia which might explain the lowered ventilatory response to hypoxia observed in human high altitude residents.6. If the carotid bodies are organs of internal secretion the finding is compatible with an increased production of a hormone produced within the type I cells.
Histochemical investigations on the human fetal subcommissural organ. II. The "large granules".
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On the innervation of the human fetal pineal gland.
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Forty-eight cases of caput ulnae syndrome treated by synovectomy and resection of the distal end of the ulna.
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[Chromosome aberrations in 334 individuals with various types of abortion (including 144 couples)].
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