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Biomedical subjects

M Mira

Publications and source records attributed to M Mira.

76 records · Page 5Linked to original sources

[Temporary disability: analysis strategies].

OBJECTIVES: To apply different regression models to estimate rate ratios for temporary sick-leave (TSL) which may occur several times in the same individual during a period, and the frequency is not constant for the observation period. SUBJECTS AND METHODS: All workers employed more than 30 days between January 1st of 1992 and June 1st of 1995 were included into the population study. The following period was 1,259 days and the total number of workers included in the study was 2,306. During that period 2,649 TSL episodes were notified, which meant 85,947 lost days. Poisson regression, Generalised Estimating Equations (GEE) and Andersen-Gill modification of Cox regression modify by Wei (WLW) were applied. RESULTS: The highest TSL incidence rates were seen in women, lesser than 30 years old, cleaners, maintenance workers and auxiliary nurses, and those involved in shiftwork. This profile was not modified after applying GEE and WLW regression models, although confidence intervals were widened. CONCLUSIONS: TSL data does not fit Poisson regression assumptions, but GEE and WLW regression models do not appear as alternatives. Other conditional regression models would need to be explored to suitably analyse this data.

Absenteeism↗

Hormonal and biochemical abnormalities in women suffering from eating disorders.

This study reports the results of a biochemical investigation of 80 eating disorder patients and results of an endocrinological investigation of 20 subjects. Of the 80 subjects studied, 22 suffered from anorexia nervosa and 51 were diagnosed as having bulimia. These patient's results were compared to those of 30 control subjects. The eating disorder patients had significantly higher levels of total CO2 calcium, alanine aminotransferase and cholesterol, and significantly lower levels of potassium, chloride and phosphate in the plasma. Hypokalaemia was strongly associated with self-induced vomiting and laxative abuse. Hypercholesterolaemia occurred most commonly in anorexia nervosa patients. Preliminary endocrinological results suggest decreased gonadotrophin levels are associated with binge eating and self-induced vomiting and laxative abuse, as well as with low weight. We feel eating disorder patients should be interviewed and examined by a physician with an interest in this area. Appropriate investigations should be ordered. The physician should also undertake counseling about the short- and long-term sequelae of disordered eating.

Adult↗