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Biomedical subjects

M Minchev

Publications and source records attributed to M Minchev.

At least 19 recordsLinked to original sources
PubMed1990

[The multiple-organ failure syndrome in intra-abdominal infections].

A specific clinical picture, characterized by affection of parenchymatous organ functions, named "multiple organ deficiency syndrome" was studied in 68 patients with intraabdominal infections. The severity of the infection was determined by practicable quantitative tests, furnishing objective assessment of the function of all affected organs. Reliable correlation was found between the number of affected organs and quantitative testing values as to the outcome of the disease. This approach however is not recommended for individual prognosis, but for classifying the patient into group with presumable mortality rate. Apart from giving precise description of the severity of infection and the patient's state, the testing is convenient for comparing groups of patients with similar diseases, also for assessment of different treatment schemes and for comparing the results of personal experience with that of other authors.

Abdomen↗
PubMed1984

Antibodies and thermolabile opsonins in the phagocytosis of human red and white blood cells pretreated with formaldehyde.

Erythrophagocytosis is conditioned by serum immunoglobulins. The extent of phagocytosis depends on the haematocrit of the red cell suspension pretreated with formaldehyde. The higher the haematocrit value, the lower will be the extent of phagocytosis. Phagocytosis of white blood cells pretreated with formaldehyde by granulocytes and monocytes is conditioned mainly by a thermolabile fraction of the serum, probably the complement.

Blood Physiological Phenomena↗
PubMed1979

[Pathogenetic and clinical significance of pentagastrin stimulation of gastric secretion in the active phase of peptic ulcer].

The gastric secretion with pentagastrin was studied in 214 subjects (130 with duodenal ulcer, 20 with double localization--in duodenum and stomach, 32 with gastric ulcer and 32--healthy). A different gastric secretory characteristic was found and the problem raised as regards the differentiated therapeutic and surgical approach in the separate tyoes of ulcer disease. The origination and clinical course of the duodenal ulcer and the ulcer with double localization are admitted to depend most likely and to a greater extent, on the gastric secretion rate. The duration of the active duodenal ulcer probably has no substantial effect on the enhanced secretory function of the stomach in the course of many years. The indices of secretion and acid elimination in single gastric ulcers are significantly diminished.

Adolescent↗
PubMed1979

[Age-related aspects of gastric secretion in duodenal ulcer during the exacerbation phase (a pentagastrin study)].

The age characteristics of gastric secretion were studied in 145 patients with duodenal ulcer and 32 healthy subjects via pentagastrin. With age advancing of the patients, a gradual reduction of gastric secretion and acidity are found, being statistically significant after the age of 49. Apart of that, the average values of the indices for each age group remain considerably higher than the normal. The age, at which the disease originated, has also a certain effect on gastric secretion. Significant reduction is observed after the age of 49, concerning only secretion volume and acidity elimination at basic conditions. The changes found in the gastric secretion and acidity are admitted to possibly play a definite role for the rather unusual course and relatively rare duodenal ulcer origination at the age of 50.

Adolescent↗
PubMed1978

[Gastric secretion study by maximal pentagastrin stimulation in healthy persons and peptic ulcer patients].

Gastric secretion was investigated in 187 subjects under conditions of maximal stimulation with pentagastrin. Thirty subjects, out of them, were healthy, 30--with gastric ulcer, 110--with duodenal ulcer and 17--with double ulcer localization--in duodenum and stomach. The indices of gastric secretion in duodenal ulcer and ulcer disease with double localization are considerably higher than those on the healthy subjects and differ essentially. With single gastric ulcer they are significantly lower than those of the healthy controls.

Adult↗
PubMed1977

[Electrolytic changes in thyrotoxicosis].

Ninety four patients with thyrotoxicosis were examined as well as 40 healthy subjects. Normal concentration of sodium, negligible chloride increase and slightly decreased potassium were established in serum. Hematocrite drops in parallel with disease severity. The average erythrocyte volume is increased whereas the average hemoglobin concentration is decreased.

Adult↗
PubMed1976

[Several functional changes in the livers of patients with diabetes mellitus].

The authors have studied the functional liver state in 107 patients with diabetes mellitus. Various stages of functional liver disturbances were found in a considerable part of them. With a few exceptions, the latter have the highest incidence and severity among the patients with decompensated, with mixed type diabetes and with remote vascular degenerative manifestations. Radioisotope investigations with 131J-Bengal pink, reveals the earliest developed changes in some of the liver functions, as compared with rest of the tests. The functional liver state is recommended to be determined in all diabetics with a view to an early detection of the developed functional disturbances and their timely treatment.

Adolescent↗
PubMed1975

[Typing of E. coli strains isolated from a turkey and a test of their sensitivity in relation to antibiotics].

The turkey-poults on an industrial turkey-breeding farm were studied. A total of 75 strains of Escherichia coli were isolated. Typing was performed by Sojka's method: serotype 0-2 was established in 42.2 percent of the cases, 0-71-- in 12.6 per cent, 0-78 (11.2%), and 0-1 (8.4%). The sensitivity of the typed strains was tested to 8 antibiotics and furazolidon. It was found that all strains possess certain amount of resistance to streptomycin, chloramphenicol, oxitetracycli, and spectam. The same strains proved sensitive to ampicillin, colimycin, tetraoleandomycin, and to a certain extent to kanamycin. It is concluded that prophylaxis and treatment should be carried out with the use of ampicillin, colimycin, furazolidon, and tetraloleandomycin.

Animals↗