Search PubMed⌕ Search

Biomedical subjects

M Micoud

Publications and source records attributed to M Micoud.

At least 91 records · Page 5Linked to original sources
PubMed1981

Angioimmunoblastic lymphadenopathy after infectious mononucleosis.

Angioimmunoblastic lymphadenopathy occurred in a 46-year-old man 16 months after an episode of infectious mononucleosis induced by Epstein-Barr (EB) virus. The features of infectious mononucleosis included fever, pharyngitis, lymph gland enlargement, hepatosplenomegaly, hyperbasophilic mononuclear cells, and IgM antibodies to EB virus, although heterophile antibodies were not detected. The illness was severe and prolonged and included an asymptomatic measles virus infection. Over a year later massive enlargement of the lymph nodes led to a biopsy, which showed a diffuse infiltration with lymphoid cells and a proliferation of arborising small vessels typical of angioimmunoblastic lymphadenopathy. In spite of corticosteroids, levamisole, chlorambucil, and radiotherapy, no remission occurred, and serious infections led to death 18 months after the onset. Viral infections with EB virus and measles virus associated with pre-existing or subsequent immunological changes probably resulted in the appearance of angioimmunoblastic lymphadenopathy.

Humans↗
PubMed1981

[Serological diagnosis of human brucellosis by means of an immunoenzymatic technic (ELISA). II.--Comparison with four other usual reactions (author's transl)].

The authors analysing 553 serums, compare the results given by ELISA, in the diagnosis of human brucellosis, with four other usual serological tests : agglutination, rose Bengal plate agglutination test, complement fixation test, immunofluorescence. In the ELISA standard study and the research of specific M component, they can estimate, experimentally, the minimal absorbance necessary for concluding in positivity. They show the excellent specificity and sensitivity of this assay, its performances are almost the same as the immunofluorescence ones. Among 55 positive serums in one assay at least 83,6% are positive in both tests ELISA and IIF and 90,9% are detected by ELISA alone.

Brucellosis↗