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Biomedical subjects

M Melzer

Publications and source records attributed to M Melzer.

48 records · Page 3Linked to original sources
PubMed1976

The status of the urinary tract in a survey of 92 cases with neurogenic bladder.

Since 1973 intermittent catheterisation was introduced in our centre and this practically eliminated pathology of the urethra. More than half of the patients had a high and complete lesion. It is our impression that 5 years following injury more than half of the patients preserved a normal upper urinary tract; however, only 39 of the 92 patients had a follow-up of over 5 years. Nephrolithiasis was rare in comparison to other reports in spite of belonging to the stone belt area. Complications of the lower urinary tract including a 10 per cent incidence of vesico-ureteric reflux were compatible with other series. Narrowing of the external sphincter on voiding cystogram should be substantiated by a profile pressure record. One female patient is a candidate for ileal conduit. Most of the patients have some form of erection but the data on ejaculation should be accepted with reserve. Two patients in this series died more than 10 years after injury, one due to a myocardial infarction and the other due to chronic renal failure following secondary amyloidosis.

Adolescent↗
PubMed1975

Pyonephrosis due to salmonella cholerae-suis variant kunzendorf.

A patient with unilateral infection of the kidney due to Salm. cholerase-suis is presented. Long-term treatment with ampicillin was of no avail. Nephrectomy terminated the infection. The extirpated kidney showed severe obstruction, stones and tissue damage.

Abscess↗
PubMed1975

The management of urologic complications after kidney transplantation.

Urologic complications occurred in four (20%) of 20 kidney transplants performed in 18 patients. The complications encountered were acute hemorrhage from the distal end of the ureter, a calyceal fistula, a ureteral stricture with associated fungus infection, and obstructive uropathy. In two of the four cases it was necessary to sacrifice the transplant.

Acute Disease↗
PubMedDate not supplied

Tuberculosis in an area bordering east London: significant local variations when compared to national data.

From September 1996 to June 1997, in an area bordering East London, we prospectively collected epidemiological, clinical and microbiological data on all patients with newly diagnosed culture-positive tuberculosis and compared these to national data based on notifications. The significant differences were that tuberculosis was diagnosed almost exclusively in non-Caucasian patients (42/47 [89%]) and that there was a high percentage of extrapulmonary tuberculosis (27/47 [57%]) including four cases of tuberculous meningitis and five cases of osteomyelitis. We also observed that 19/27 (70%) of patients with extrapulmonary tuberculosis had normal chest X-rays, 3/17 (18%) sub-Saharan Africans were HIV antibody-positive and drug resistance strains were isolated from six sub-Saharan Africans and one Caucasian. Figures for treatment failures and mortality compared favorably to national averages at 6 months. National data do not accurately reflect local epidemiology and clinical presentations. Hospital-based surveillance and promoting awareness of local differences is essential to prevent delayed diagnosis, inappropriate management and poor clinical outcome.

Adolescent↗
PubMedDate not supplied

[Effect of environmental factors on the composition of lipopolysaccharides released from the Rhodobacter capsulatus cell wall].

The goal of this study was to compare the environmental factors that determine viability of the gram-negative photosynthesizing bacteria Rhodobacter capsulatus (specifically, light and growth medium composition) and to assess the effect of these factors on the synthesis and composition of lipopolysaccharides released from the cell wall. Depletion of medium resulted in the release of lipopolysaccharides with a truncated polysaccharide fragment. It is concluded that, due to high viability of these bacteria, the main factor that induced lipopolysaccharide release from the cell wall, irrespective of culturing conditions, is cell division rather than cell death.

Cell Wall↗