Effects of ethidium bromide on mitosis and chromosomes: a possible material basis for chromosome stickiness.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to M McGill.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A case is reported of an alloimmunized, neonatal, thrombocytopenic patient who was successfully transfused with maternal platelets collected by cytapheresis and cryopreserved 3 months before delivery. Phlebotomy or cytapheresis of the mother immediately before delivery was avoided. Transfusion of maternal platelets over a 7-day period with aliquots containing an average of 7.1 X 10(10) platelets in 50 ml of plasma was possible. Satisfactory increases in platelet counts were sustained after transfusion.
Foot ulceration due to neuropathy is a serious cause of morbidity in diabetes. Ulceration usually occurs at the part of the foot subjected to excessive mechanical pressure. A more generalized increase in pressure under the feet has also been shown to be a feature of many patients with diabetic neuropathy. In this study the electrodynogram was used to measure the pressure at seven positions under each foot. The maximum vertical foot bearing pressure was found to be higher in 11 diabetic patients with previously healed unilateral foot ulcers (10.6 +/- 5.9 kg cm-2) than in 11 diabetic patients who did not have such a history (4.2 +/- 1.3 kg cm-2). However there was no difference in pressure between the foot with previous ulceration and the contralateral foot (9.7 +/- 6.8 kg cm-2, 11.6 +/- 7.9 kg cm-2). Vertical foot bearing pressure was decreased by an average of 18% by wearing shoes padded with a Professional Protective Technology insole and the decrease was greater in patients with higher foot pressure. These results showed that increased vertical foot pressure is an important, but not the only, factor in determining the occurrence of foot ulcer.
How can we improve the process of patient care and satisfaction? One way is to improve methods of transmitting, storing and manipulating information. That answer puts technology at the very core of health care.
Diabetes is reaching epidemic proportions in many countries of the world and the World Health Organization (WHO) predicts a tripling of the current prevalence rates by 2025. In reality there will not be sufficient physicians to cope with this epidemic. One solution is to utilize highly skilled allied health professionals to do much of the routine diabetes education and management. Convincing hospital administrators of this need, however, can be problematic especially when for many years the focus of the health service has been on communicable diseases. Selection of appropriate staff is very important as they will need to take on much of the burden of the work. Of course these staff require comprehensive clinical training beyond what is expected of most health professionals. In addition to this, it is generally recognized that a multidisciplinary team is an effective method of providing diabetes care. However, a multidisciplinary team is not simply the sum of different health professionals who work independently. Rather, the various members of the diabetes health care team, while working within their own scope of practice, need to integrate their roles to complement each other and blend together. Diabetes is one of the foremost health challenges facing the world in the new millennium. It has the potential to overwhelm health budgets. Health administrators and health service planners need to heed the warnings as the toll from this serious disease mounts.
Explore the source record for details and available documents.