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Biomedical subjects

M Massin

Publications and source records attributed to M Massin.

At least 55 records · Page 3Linked to original sources
PubMed1985

Nickel allergy: analysis of metal clothing objects and patch testing to metal samples.

In 22 nickel-sensitive subjects, 57 metal clothing objects were said to be not tolerated (37) or tolerated (20). They were analysed by X-ray energy dispersion in electron microscopy, and by the dimethylglyoxime spot test. The correlation between the analytical results and the statements of patients is discussed. Patch tests to nickel-plated metal samples with various thicknesses of chromium (0.25 mu to 1 mu) or gold/copper/cadmium (0.5 mu) were performed in human subjects or in guinea pigs sensitive to nickel. Surface-plating and anticorrosive techniques, as well as the results in nickel-sensitive subjects, are described and discussed. Good tolerance will not be obtained under experimental conditions if nickel in any form is a component of the object. It is to be hoped that appropriate regulations will prohibit the use of nickel in the manufacture of clothing objects.

Adolescent↗
PubMed1985

[Specular microscopy in the diagnosis of the iridocorneal endothelial syndrome].

Irido-corneal endothelial syndrome regroups three disorders including: endotheliopathy, peripheral anterior synechiae and iris changes. According to the aspect of these abnormalities, three syndromes are described: essential iris atrophy, Chandler's syndrome and iris naevus (Cogan-Reese) syndrome. Endothelial changes studied by specular microscopy are typical: in early stages, a rounding off cell angles and intracellular blackout areas can be seen; in former stages, black out areas increase and there is a disruption of the regular mosaic. These features are a major point for differential diagnosis. We present six cases reports among which three where effectively diagnosed as iridocorneal endothelial syndrome and three were not.

Adult↗
PubMed1985

[Anti-inflammatory effect of tiaprofenic acid following ocular surgery].

We evaluated the anti-inflammatory and analgesic action of tiaprofenic acid in the post-operative course of ocular surgery by means of a double-blind study versus placebo in a series of 85 patients. 41 of these patients received tiaprofenic acid and 44 received the placebo. Tiaprofenic acid was administrated at a dose of 600 mg/day according to a peri-operative therapeutic plan (2 days before and 6 days after the operation). The results demonstrate that the anti-inflammatory action of tiaprofenic acid is significantly better than that of the placebo and that it is very rapid, appearing on the day after the operation. The tolerance was very good and identical in the two groups. The use of tiaprofenic acid in ocular surgery results in a significant reduction in the intensity and the duration of the inflammatory reaction.

Anti-Inflammatory Agents, Non-Steroidal↗