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Biomedical subjects

M Massari

Publications and source records attributed to M Massari.

62 records · Page 4Linked to original sources
PubMedDate not supplied

[Group B beta-hemolytic Streptococcus: study on colonization of mother-neonate couples observed in January-May 1988 at the obstetrics and gynecology unit and the neonatal section at the Pistoia Hospital].

In a previous study, carried out on women at delivery recovered at the obstetric ward of the Pistoia Hospital, we noted a high incidence of group B Streptococci cultured from vaginal site. Because group B streptococcal infection is very serious in neonates we decided to examine the frequence of vertical and horizontal transmission among the mother-neonate couples. We have also compared their rate of colonisation by doing rectal and vaginal swabs on women and rectal, vaginal and external auditory canal swabs on babies. In fact we known that infants moderately to heavily colonised with group B Streptococci at birth, appear to have a significant higher risk of developing serious disease than do infants only lightly colonised. In our work we haven't observed any acute group B streptococcal infection, but we have identified 18 couples mother-neonate colonised by the same group B Streptococci serotype, which is proof of an easy vertical transmission of group B Streptococci whilst horizontal transmission is very rare (only one case).

Female↗
PubMedDate not supplied

[Treatment of differentiated carcinoma of the thyroid and its limitations].

The Authors report their experience in the management of differentiated thyroid cancer (DTC) with extrathyroidal extension including nodal and distant metastases. Twelve patients were included in the review: 11 of them were previously and elsewhere considered not curable. On the contrary, integrated treatment (surgery, radioiodine and radiation therapy) allowed to control the disease in 10 patients with a survival ranging from 14 years to 29 months. Cytopathologic analysis, in the two patients who died, showed a differentiated thyroid cancer with anaplastic areas. Integrated treatment, therefore, represents the treatment of choice for advanced DTC only in total absence of anaplastic cells.

Humans↗
PubMedDate not supplied

[The sternotomy and thoracotomy approaches in the treatment of differentiated thyroid cancer in an advanced phase].

The authors report their experience in the treatment of well-differentiated thyroid cancer. The analysis of 5 cases treated with extensive surgery give the opportunity to discuss about the use of sternotomy or thoracotomy to eradicate mediastinal lymph nodes. The importance of preoperative assessment, especially by histological examination is stressed as well as the role of surgery in the multidisciplinary approach for the treatment of the disease.

Adenocarcinoma, Follicular↗
PubMedDate not supplied

Endoscopic ultrasonography for preoperative staging of gastric carcinoma.

BACKGROUND/AIMS: To assess the accuracy and limitation of endoscopic ultrasonography in preoperative staging of gastric cancer, we performed a prospective study on 99 patients. MATERIAL AND METHODS: Ninety-nine patients with gastric cancer had preoperative staging with endoscopic ultrasound (EUS) and CT. RESULTS: The depth of infiltration (T parameter) was correctly defined by EUS in 58/65 patients (89%). The lymph node involvement (N parameter) was correctly classified in 44/65 patients (68%), the sensitivity was 74% and the specificity was 54%. The most frequent cause of understaging T parameter was microscopic tumor invasion, whereas overstaging was due to peri-tumor inflammation. CONCLUSIONS: We believe that EUS is a reliable method, superior to all diagnostic tools, in the evaluation of locoregional extension of gastric cancer.

Endosonography↗
PubMedDate not supplied

Ultrasonographic imaging of neoplasms of the cervical esophagus.

BACKGROUND/AIMS: We studied the effectiveness of ultrasonography in evaluating the cervical esophagus for the presence of large masses arising from the esophageal wall and consequently, the modifications of the visceral lumen. MATERIALS AND METHODS: The cervical esophagus can be evaluated by ultrasound with longitudinal and axial scans, using the left thyroid lobe as an acoustic window. The cervical esophagus can be visualized from the C5 to D2 vertebrae. From November 1992 to July 1996, 220 patients with esophageal cancer and 120 subjects without esophageal disease (control group) were examined with ultrasonography. Examination of the cervical esophagus was performed with a linear high definition small parts probe with a frequency of 7.5-10 Mhz. RESULTS: In all 31 patients with cancer of the cervical esophagus, ultrasonography of the cervical region showed the presence of an expanding mass from the esophageal wall as well as the modifications in the visceral lumen. The neoplasm of the cervical esophagus was visualized when its diameter exceeded 5 mm. CONCLUSIONS: The experience of the authors shows that, during ultrasound examination of the cervical region, it is possible to accurately evaluate the cervical esophagus, either morphologically or functionally.

Aged↗
PubMedDate not supplied

Evaluation of leiomyoma of the esophagus with endoscopic ultrasonography.

Fourteen patients with suspected leiomyoma of the esophagus were studied by endoscopic ultrasonography, computed tomography, endoscopy and barium swallow. The results were correlated with the histology of the resected specimens: in 2 patients with a peduncolated leiomyoma originating from the second echographic layer, endoscopic resection was performed. Endoscopic ultrasonography was superior to other imaging techniques in detection and staging of leiomyoma because it can determine the layer of origin, the direction of the growth and the consistency of the tumor.

Adult↗
PubMedDate not supplied

Endoscopic ultrasonography in the evaluation of leiomyoma and extramucosal cysts of the esophagus.

BACKGROUND/AIMS: Leiomyoma is the most common type of benign esophageal tumor, whereas extramucosal cysts of the esophagus are congenital anomalies frequently asymptomatic in the adult and in most cases detected incidentally on chest x-ray. It is worthwhile considering these conditions together, because they present similar diagnostic and surgical problems. Conventional imaging tests do not lead to a precise diagnosis. The purpose of this study was to evaluate the use of endoscopic ultrasonography in the diagnosis of, and planning of treatment modalities for, these conditions. METHODOLOGY: Fifteen patients with esophageal leiomyoma and seven patients with extramucosal esophageal cysts were studied with endoscopic ultrasonography using an Olympus GF- EU-M3 instrument with a 7.5-12 MHz echoprobe. In all patients, the results of endoscopic ultrasonography were compared with the histology of the resected specimens. RESULTS: The histology of the resected specimens confirmed the endosonographic diagnosis in all patients. No malignancy was found in any specimen. CONCLUSIONS: Endoscopic ultrasonography is very accurate in visualizing these lesions and differentiating cystic from solid submucosal esophageal masses; in addition, the test can establish the exact location of the mass in relation to the esophageal wall and mediastinum. Therefore, endoscopic ultrasonography has a great impact in confirming the diagnosis of leiomyoma and extramucosal cysts of the esophagus and facilitates therapeutic decision-making because of its capacity to clearly define the size, layer of the origin, and pattern of the mass.

Adult↗