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Biomedical subjects

M Martelli

Publications and source records attributed to M Martelli.

At least 127 records · Page 7Linked to original sources
PubMed1979

Present tendencies in the surgical treatment of pectus excavatum.

Among the malformations of the chest wall, pectus excavatum is undoubtedly the most frequent. It may appear in various forms and may show varying degrees of severity. Surgical correction by operation is mostly sought by the patients for aesthetic reasons. After careful review of the methods proposed by various writers for the correction of this malformation, the present writers emphasize the advantages and disadvantages of these techniques, especially in relation to the methods of stabilising the reduction. Finally, they report on their own case material and present some significant examples.

Adolescent↗
PubMed1978

Daunomycin, cytosine arabinoside and 6-thioguanine (DAT) vs vincristine, cytosine arabinoside and 6-thioguanine (VAT) in the induction treatment of acute nonlymphocyte leukemia: a randomized collaborative study.

One hundred patients were entered in a cooperative study comparing the efficacy of two different regimens in the induction treatment of acute nonlymphocytic leukemia (ANLL). Patients were randomly allocated to receive either the DAT or VAT combination; half of the patients were also randomized to receive CNS prophylaxis including intrathecal methotrexate + prednisone and cranial irradiation. Consolidation and maintenance therapy were uniform in responding patients. Out of 82 evaluable patients 41 (50%) attained complete remission (CR) with no significant difference between the two regimens. Median remission duration was slightly longer in the DAT group (32.5 vs 22 weeks); median survival was 34 weeks for all evaluable patients with no difference between the two schedules. Meningeal relapse occurred only in two patients after 19 and 99 weeks of continuous remission. Fourteen patients are still alive after 61 to greater than or equal to 155 weeks, of whom seven are in their initial remission (six in the DAT and one in the VAT group). We conclude that 1) DAT and VAT are equally effective in inducing CR in a high proportion of ANLL patients; 2) until marrow remission can be prolonged significantly, preventing CNS leukemia will not have any significant impact of the course of ANLL.

Adolescent↗
PubMed1977

[Pre- and postoperative treatment of pulmonary suppuration].

A group of patients presenting a pathology of pulmonary suppuration is examined and a type of basic treatment used for preparing such patients for surgery, not always indicated by suppuration, is presented. A number of clinical and functional parameters measured before and after such treatment are also examined. The therapy carried out personally in the immediate postoperative period and in the long term is illustrated.

Cephalexin↗