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Biomedical subjects

M Markova

Publications and source records attributed to M Markova.

10 recordsLinked to original sources
PubMed1979

[Effect of a dietary regimen with separated administration of protein on liver in the rat].

Rats received a protein-deficient standard diet and, separately at different hours of the day, protein (casein). The control group was given the standard diet added with casein. The livers of the rats were examined for histological and ultrastructural changes. The smallest changes were observed in animals which had received protein at eight o'clock. The control animals and the animals which had received protein at thirteen and nineteen o'clock, respectively, showed slight fatty infiltration of the liver.

Animals↗
PubMed1979

[Effect of the protein intake on the rhythm of assimilation in white rats with proportioned feeding].

Experimental data on the influence of separate protein feeding by giving milk cassein at different hours of the day and night, apart from the energy-supplying food, to young rats, showed that protein is best utilized by the organism when given durins the dark period of the day. The results obtained are discussed in relation to the coefficients of protein and caloric effectiveness in the different hours of the day and night, with regulation of the light and dark period for 24 hours.

Adaptation, Physiological↗
PubMed1972

[Chylothorax].

Explore the source record for details and available documents.

Adult↗
PubMedDate not supplied

Response of rat lung to N-hexane and whole-body x-irradiation given solely or combined.

Biochemical, cytological and morphological studies in Wistar male rats. For N-hexane inhalation treatment, dynamic exposure chambers maintaining a concentration of 5,500 mg/m3 over 5 hours per day were used for 8 days. Immediately there after, the animals were given a single whole-body exposure to 4 Gy X-rays. Bronchoalveolar lavage fluid (BALF) was obtained from removed lungs. Lung homogenates were prepared subsequent to intracapillary lung perfusion via the right cardiac ventricle. Short-term n-hexane inhalation treatment was found to increase BALF total cell counts, predominantly alveolar macrophages (AM); elevated activities in lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) evidenced injury affecting type I and type II pneumocytes over early post-treatment times. Whole-body irradiation alone moderately decreased AM numbers in respiratory pathways. Exposure to both agents combined resulted in depressed activity of a major antioxidant enzyme, superoxide dismutase, and diminished contents of nonprotein sulfhydryl groups in the lungs. Most of the endpoints recorded underwent greater change in the case of combined treatment, indicating synergistic action of n-hexane and ionizing radiation with regard to the biological effects studied.

Animals↗