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Biomedical subjects

M Maresh

Publications and source records attributed to M Maresh.

50 records · Page 3Linked to original sources

Low energy diets in the treatment of gestational diabetes.

A randomised prospective study of treatment with dietary restriction alone or insulin therapy with dietary advice was performed in 15 women with glucose intolerance diagnosed early in the third trimester of pregnancy. Twenty-four hour profiles of plasma glucose and 3-hydroxybutyrate were performed before and four weeks after commencing treatment. The effect on neonatal outcome was assessed. The case history of one of the patients in the study was sent to British physicians with a special interest in diabetes to obtain their opinion about the appropriate initial treatment of women with gestational diabetes.

3-Hydroxybutyric Acid↗

An obstetric microcomputer information system.

A systems analysis has been done to determine how computer technology can provide an information system to improve the care of the mother and her baby. A minimum data base was established complying with the recommendations of the Körner Committee and designed to meet the needs of the health personnel looking after the mother and baby. An ICL DRS 20/50 network of four microcomputers has been installed in the obstetric unit of a district teaching hospital with a link to the regional mainframe. There have been no significant software or hardware faults since the system became fully operational in January 1984. All women are registered on the system at their first visit allowing the pregnancy to be followed prospectively. Subsequently midwives enter data on line at delivery and at discharge. The on line validation and range checks improves the accuracy of the data allowing a reliable perinatal audit to be obtained routinely. The system has been accepted by the staff since much of the routine pregnancy documentation is produced automatically. This includes booking letters and summaries for general practitioners, admission slips, birth notification forms, registers and forms for the community midwives and health visitors. Immediate production of reports for community health staff allows better communication and improved patient care. No additional staff are needed in the obstetric unit and one job which was mainly of a clerical nature has been saved and the salary transferred to provide one more midwife for the postnatal wards.(ABSTRACT TRUNCATED AT 250 WORDS)

Computers↗

The effect of diet and insulin on metabolic profiles of women with gestational diabetes mellitus.

Twenty women with abnormal glucose tolerance, detected from a routine program of antenatal screening for gestational diabetes mellitus (GDM) at 28 wk, were admitted for 24-h metabolic profiles. They were then alternately allocated to either insulin and dietary restriction or dietary restriction alone and then retested 4 wk later while on therapy. Ten normal controls were assessed twice at similar gestations to the study group. Before treatment, the 20 gestational diabetic subjects had higher mean concentrations of plasma glucose and 3-hydroxybutyrate than the controls for most of the profile, but mean insulin values were similar. Insulin therapy was associated with a reduction in mean glucose concentrations so that the profile was similar to the controls, while in the diet-alone group the reduction was less. The 3-hydroxybutyrate concentrations rose between profiles in the normal group and also rose in those treated by diet alone, but still remained within the upper range of normal even at night. Insulin therapy resulted in a similar 3-hydroxybutyrate profile to the controls. The C-peptide response to breakfast was reduced in both groups to levels below that of the controls. Neonatal outcome indices were similar in the two treatment groups, despite the differences in maternal metabolites, but because of the size of this study, conclusions about the neonate must be tentative.

3-Hydroxybutyric Acid↗

Selection of an obstetric data base for a microcomputer and its use for on-line production of birth notification forms, discharge summaries and perinatal audit.

A microcomputer system is described which stores data for perinatal audit and produces 'on-line' the statutory birth notification form and mother and baby discharge summary. The derivation of a minimum data-base and the methods used to obtain reliable data are outlined. The results of a trial of the production of the birth notification form for 195 deliveries are reported together with those of a further trial of 86 deliveries in which the system was used to produce both the notification form and the discharge summary. A study of the accuracy of the handwritten birth notification forms revealed a high error rate which was markedly reduced by the use of the microcomputer system. The system is now in routine use and further developments are outlined.

Computers↗

Delayed pushing with lumbar epidural analgesia in labour.

Seventy-six primigravidae with epidural analgesia were randomly assigned to one of two groups for management in the second stage. In one group the women delayed pushing and in the other they were managed conventionally. The two groups were well matched for maternal and infant characteristics, including position and level of the presenting part at full dilatation and fetal scalp blood pH. The mean waiting time in the second stage before pushing was increased from 27 min in the conventional group to 123 min in the delayed group. This delay was not associated with an increase in abnormal fetal heart rate abnormalities or any decrease in umbilical cord pH or Apgar scores. In contrast, the delay was associated with an increase in spontaneous deliveries and a decrease in forceps deliveries (P = 0.06). These findings suggest a need for redefining the management of the second stage of labour with epidural analgesia.

Adult↗

Computers in obstetrics.

Computers are being used increasingly often in obstetrics for many applications from producing routine documentation to research, and from audit to helping decision making. This article attempts to span this whole field to give a feel for the uses to which we should be putting the computer.

Decision Support Techniques↗