[Tumors of the smooth muscles of the uterus with epithelioid and star-like sclerotic appearance].
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Biomedical subjects
Publications and source records attributed to M Marchini.
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Endometrial biopsies were obtained in 12 volunteers between 18 and 35 years old who had used SHB 209 AE oral contraceptive during the previous six months. Three main types of endometrial patterns were observed: proliferative, very similar to a normal proliferative phase; early secretory: similar to early postovulatory endometrium; late secretory: characterized by diffuse predecidual changes in the stroma. At SEM after one week a great prevalence of nonciliated cells was observed. During the 2nd and the 3rd week, the endometrial surface appears still flattened with scanty glandular outlets.
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In 21 infertile patients, operated on for bilateral hydrosalpinges, multiple tubal biopsies, removed during surgery, were studied by light microscopy and scanning electron microscopy. Compared with control biopsies, taken from 12 fertile women, all cases but one showed flattening or loss of major and minor mucosal folds and epithelial deciliation. However postsurgical fertility rate, after 1-3 years follow-up, is not proportional to the percentage of ciliated cells.
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One case of left fallopian tube prolapse following vaginal hysterectomy is reported. Modifications of the endosalpinx at S.E.M. show a mucosa relatively resistant to biological assault.
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Three cases of hydrocolpos observed in the Milan Department of Obstetrics and Gynecology and of Pediatric Surgery are described. Two of them were cases of simple imperforated hymen whereas the third had a vaginal obstruction associated with microcephaly and polydactily. The diagnosis was based on vaginography and urography and the treatment on resection of the vaginal membrane in two cases and in laparatomic Leadbetter-Politano's operation in the third. The Authors stress the importance of a very early diagnosis for a definitive treatment and a good prognosis and also the interest of a follow-up of these patients.