Search PubMedSearch

Biomedical subjects

M Manfredini

Publications and source records attributed to M Manfredini.

8 recordsLinked to original sources

An epidemiological study on severe mental retardation among schoolchildren in Bologna, Italy.

The prevalence, causal origin of and impairments associated with severe mental retardation (SMR) were investigated among all school-age children (six to 13 years) living in the city of Bologna, Italy. 90 children (57 boys, 33 girls) with IQs less than or equal to 50 were identified. The prevalence of SMR was 4.2 per 1000 for males, 2.5 per 1000 for females and 3.4 per 1000 for both sexes. Causal origin was prenatal for 33.3 per cent, perinatal for 14.4 per cent, combined pre- and perinatal for 5.6 per cent and postnatal for 13.3 per cent. Another 12.3 per cent of the children with IQs less than or equal to 50 had autism or childhood psychosis, while there was no evident cause of mental retardation for the remaining 21.1 per cent. 50 per cent had at least one associated physical or neurological impairment other than mental retardation, with epilepsy and cerebral palsy predominating.

Adolescent

CT and plain X-ray examination of the skull in pure traumatic laceration of the brain.

The authors reviewed a series of 68 brain lacerations. Patients with associated subdural hematomas and/or depressed skull fracture were excluded from this study. The material has been divided in three groups: mainly hypodense, mainly hyperdense and mixed lesions. Clinical outcome was evaluated according to the various features of parenchymal lesions: CT aspect, mass effect and site. The presence of a considerable amount of blood suggests an unfavourable prognosis while the site and the mass effect do not seem to influence the course of the disease.

Brain

Iopamidol vs. metrizamide myelography: clinical comparison of side effects.

One hundred myelographies with iopamidol and 100 with metrizamide were performed in order to compare the side effects of the two contrast media after injection into the spinal subarachnoid space. All patients were observed for a follow-up period of at least 4 days. The most frequently observed side effect, headache, was more common, of longer duration, and more severe with the use of metrizamide than with iopamidol. Only neck pain was more common with iopamidol. More severe side effects such as meningeal irritation, psychoorganic syndrome, and epileptic seizures occurred only with metrizamide. The results seem to indicate a lower neurotoxicity and better patient tolerance for iopamidol than for metrizamide.

Adult

Focused encephalography.

Focused encephalography is a diagnostic procedure performed after computed tomography (CT) that can be specifically focused on diagnostic problems not solved by CT. The authors have used the procedure in 20 cases, and it has proved to be quick, risk-free, and without serious side effects. It provides useful supplementary diagnostic information, and can be especially helpful when CT is not available or when the CT scanner is an early-generation model.

Brain Diseases