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Biomedical subjects

M Maleki

Publications and source records attributed to M Maleki.

30 records · Page 2Linked to original sources

Venospastic phenomena of saphenous vein bypass grafts: possible causes for unexplained postoperative recurrence of angina or early or late occlusion of vein bypass grafts.

Angina recurred in a 54 year old white man after multivessel coronary artery bypass surgery. Fourteen months after operation the frequency and intensity of his mixed angina increased and cardiac stress testing was positive. Repeat cardiac catheterisation showed that all the bypass grafts were widely patent; however, spasms of a vein graft to right coronary artery system were clearly seen. Treatment with calcium blocking agents and long acting nitrates abolished the symptoms during 16 months of clinical follow up.

Cardiac Catheterization↗

Atypical xanthoastrocytoma presenting as a meningioma.

A 15-year-old boy was admitted to excision of a large exophytic right parietal tumor, which, on computed tomography scans and angiograms, revealed marked contrast-medium enhancement in infusion studies. Angiographic studies showed meningeal feeders, which suggested a meningioma. Computed tomography scans demonstrated extensive erosion of the skull, which indicated a slowly growing process. Pathologically it shared many features with pleomorphic xanthoastrocytomas, suggesting that neoplasia of the glia limitans may have a wide range of clinicopathological manifestations, including a favorable long-term prognosis.

Adolescent↗

Arteriovenous malformations of the posterior cerebral hemispheres.

Arteriovenous malformations (AVMs) of the brain usually present with acute hemorrhage or epilepsy. Of 54 patients with AVMs limited to the posterior cerebral hemispheres some 60% had intermittent or acute visual symptoms. Most had homonymous hemianopia. Because of the possible neurologic consequences of an AVM it is important to distinguish the headaches and visual symptoms of this lesion from those of classic migraine, a more common condition. In this paper this differentiation and the pathogenesis of the symptoms are reviewed.

Adolescent↗

Primary sclerosing cholangitis.

Two new cases of primary sclerosing cholangitis with a rapid fatal course, particularly the patient in Case 2, are presented. Primary sclerosing cholangitis is a rare condition of unknown cause presenting with extrahepatic biliary obstruction due to a chronic inflammatory obliterative process with the absence of stones, cancer, or previous biliary surgery. This condition is often associated with ulcerative colitis, retroperitoneal fibrosis, and Riedel's thyroiditis. Surgical treatment for promoting bile drainage and long-term corticosteroid therapy are effective palliative measures.

Cholangitis↗