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Biomedical subjects

M Maldonado

Publications and source records attributed to M Maldonado.

86 records · Page 5Linked to original sources
PubMedDate not supplied

Seroprevalence and sociocultural conditionants of Chagas disease in school-aged children of marginal zones of Asunción.

Chagas disease is becoming a public health problem in Latin America due to the wide distribution, the high prevalence, the magnitude of the damage caused and the difficulties to control it. In Paraguay, the disease is mainly distributed in the departments of Paraguarí, Cordillera and Central. Prevalence in marginal zones, where migrations from rural populations and endemic areas make possible the urbanization of the disease, has no been studied yet. This is a descriptive study with a cross-sectional sampling and a probabilistic system recruitment carried out in school aged children from marginal zones of Asunción to determine the prevalence of Chagas' disease. Serological methods, parasite isolation and questionnaires were used to achieve the goals. Nine hundred and fifty three children were studied to determine the prevalence of Chagas' disease in marginal zones which was 1.4%.

Adolescent↗
PubMedDate not supplied

Sarcoidosis after surgically induced remission of Cushing's disease.

OBJECTIVE: To describe a rare case of sarcoidosis diagnosed after surgical resection of an adenoma in a patient with Cushing's disease. METHODS: We present a case report and discuss the only other similar case identified from the published medical literature. RESULTS: In a 33-year-old woman with symptoms of cortisol excess (including progressive weight gain, proximal muscle weakness, ecchymoses, and amenorrhea), laboratory studies showed serum cortisol values consistent with Cushing's syndrome. After inferior petrosal sinus sampling, the patient underwent surgical resection of an adenoma in the right aspect of the anterior pituitary gland. Maintenance corticosteroid therapy was implemented, and the signs and symptoms of Cushing's disease began to resolve. Five months postoperatively, multiple erythematous lesions developed on the patient's arms and legs. Skin biopsy specimens demonstrated noncaseating granulomas, and sarcoidosis was diagnosed. Two months later, the lesions resolved spontaneously without therapy other than continued corticosteroid replacement. CONCLUSION: Physicians should be aware that unusual postoperative symptoms in a patient who has undergone successful treatment of Cushing's syndrome may be attributable to the emergence of another corticosteroid-responsive disease such as sarcoidosis.

Journal Article↗
PubMedDate not supplied

[The psychometric characteristics of the Depression Scale of the Centro de Estudios Epidemiológicos in adult Mexican women from rural areas].

This paper presents the results of a study aimed at describing the characteristics of the CES-D in a sample of 250 adult women, residents of rural areas in the Mexican states of Jalisco and Michoacán. Our factor analyses did not replicate the factor structure of the original scale, but adequately grouped the items according to their conceptual meaning. The CES-D was found to possess a high internal consistency (Cronbach's Alpha .92) besides being strongly correlated with the measures used to assess the scales's criterion validity. Caution is recommended when using this scale with rural women, especially when interpreting the results which should incorporate not only the total scores but also the evaluation of the presence and persistence of specific symptoms in the particular sociocultural context of the studied population.

Adult↗