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Biomedical subjects

M Majstorović

Publications and source records attributed to M Majstorović.

11 recordsLinked to original sources

Hypohidrotic ectodermal dysplasia: dental features and carriers detection.

Ectodermal dysplasia is a heterogeneous condition characterized by affected ectodermal structures, among which the teeth and skin with its derivatives (hair sweat glands) are the most frequent. The aim of this work is to present the analysis of dental traits in five families (affected boys and their mothers) with hypohidrotic ectodermal dysplasia (HED), and to evaluate the importance of orofacial and dental findings in the determination of female HED gene carriers. Hypodontia (oligodontia) was found in all the patients. The mothers, gene carriers, had either hypodontia or a reduced size of teeth with a particular morphological, peg shape. In patients with hypohidrotic ectodermal dysplasia the deciduous second molar teeth were mostly affected by taurodontism. The characteristic dental finding in heterozygous females of the mandibular peg shaped incisors and canines, as well as of hypodontia or peg shaped upper lateral incisors can be used as a reliable criterion for the detection of HED gene carriers.

Adult↗

Factors predicting a child's dental fear.

The aim of the present study was to determine and assess the variables most involved in the etiology of a child's dental fear. The study was performed on a sample of 89 children aged from 5.5 to 12.5 years and their mothers. The sample comprised 37 children with experience of dental trauma (19 boys and 18 girls) and 52 children without experience of dental trauma (28 boys and 24 girls). Corah Dental Anxiety Scale (DAS) was applied to evaluate the level of the child's (CDAS) and mother's (MDAS) dental anxiety. Broome's Child Medical Fear Questionnaire (CMFQ) was used to assess the child's fear of medical treatment. Hollingshead Two Factor Index of Social Position (ISP) was calculated to assess socio-economic status of the family. Cluster analysis differentiated one group of dentally anxious children with the highest level of maternal anxiety (MDAS = 14.44) and the lowest socio-economic status (ISP = 41.94). Another group of extremely anxious children (CDAS = 14.31) showed the highest fear of medical treatment (CMFQ = 22.08) and rather low socio-economic status. One group represented children with the lowest CDAS (5.63), lowest MDAS (8.46), and lowest CMFQ (13.54). Linear regression analysis showed high correlation between previous traumatic medical experiences and a child's dental anxiety using the linear model CDAS' = b0 + b1 x CMFQ. The analysis revealed that a child's dental fear mostly depends on early negative medical experience, while material dental anxiety and socio-economic circumstances seem to be of less importance.

Adult↗

[Intrauterine development of newborns of mothers with diabetes mellitus].

The examination of 170 babies born to diabetic mothers revealed that the body weight of these children was by a significant percent higher than that of other babies of the corresponding gestation age. Hypertrophic babies are born more frequently to mothers with manifest diabetes than to those with gestation diabetes. In mothers with the long-lasting disease accompanied by vascular lesions, retardation of the intrauterine fetal growth may occur. In order to improve the condition of these infants, their mothers should be constantly supervised during pregnancy and they should be prescribed adequate diet and therapy. Diabetic mothers also require greater care at delivery and a more liberal attitude towards the application of the cesarean section in order to prevent hypoxia and obstetric traumas of the infant.

Adult↗