Responses of autoimmune factor VIII inhibitors to a combination of cyclophosphamide and prednisone.
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Autoantibodies↗
Biomedical subjects
M Maigre
Publications and source records attributed to M Maigre.
A lymph node interdigitating reticulum cell sarcoma.
A 20-year-old woman presented with bilateral cervical, supraclavicular, and mediastinal lymphadenopathy. A nodal biopsy specimen showed a diffuse malignant proliferation of large pleomorphic cells. The ultrastructural features and the antigen phenotype (expression of HLA-DR, CD68, alpha 1-antichymotrypsin, and S100 protein and inconstant reactivity for CD11c, CD15, and peanut agglutinin) were consistent with a derivation from interdigitating reticulum cells. Despite intensive combination chemotherapy with autologous bone marrow transplantation and local irradiation, the patient relapsed in the initial sites of the disease. A review of 12 previous reports of interdigitating reticulum cell sarcomas showed that most of these rare tumors behaved aggressively and were unresponsive to classic intensive chemotherapeutic regimens.
Adult↗
[Biermer's anemia].
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Anemia, Pernicious↗
[Systemic mastocytosis and malignant hemopathies. Review of the literature apropos of a case].
The authors report the case of a 68-year old woman with systemic mastocytosis revealed by spleen enlargement and portal hypertension, and associated with chronic myelomonocytic leukaemia. Based on their review of the literature, they describe the general characteristics of systemic mastocytosis and underline the frequent association of this disease with malignant haematological disorders, notably in the myeloid series.
Aged↗
[Pseudo-septicemic pyoderma gangrenosum and breast cancer. Apropos of a case caused by an intramuscular injection].
We report a case of pyoderma gangrenosum (PG) mimicking a severe infectious skin disease in a woman with metastatic breast cancer. PG started at the site of an intramuscular injection administered a few days previously, and it subsequently extended. The skin disease was cured by high-dose corticosteroid therapy and clofazimine, but it marked a turn for the worst in the course of the breast cancer which became rapidly fatal.
Breast Neoplasms↗