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Biomedical subjects

M Mackay

Publications and source records attributed to M Mackay.

At least 73 records · Page 4Linked to original sources
PubMed1985

Asthma in a country hospital.

All 39 adult asthma admissions to Kaitaia Hospital in 1983 were surveyed. Of 15 patients treated by a doctor prior to admission, only one received treatment likely to abort the attack. Twenty-four patients were supposed to be taking beclomethasone or cromoglycate but only six were taking it regularly with an adequate inhaler technique. The possibility of erratic use of beclomethasone being a contributing factor in the high mortality from asthma in New Zealand is raised. Of 15 patients not taking beclomethasone or cromoglycate, 10 gave a history suggesting they could have benefited from such medication. Twenty-eight of the admissions were thought to have been potentially preventable.

Adolescent↗
PubMed1985

The gene for an exported antigen of the malaria parasite Plasmodium falciparum cloned and expressed in Escherichia coli.

An exported protein of the erythrocytic stages of the malaria parasite, Plasmodium falciparum, has epitope(s) in common with the surface of the sporozoite stage (1). Two cDNA clones encoding this protein, Ag5.1, have now been isolated and expressed in Escherichia coli. The coding sequence contains a region with strong homology to that of the circumsporozoite protein of P. falciparum. Other features of the sequence can be explained in terms of the observed behaviour of the protein in the parasite life cycle. The Ag5.1 can now be synthesised in bacteria in sufficient amounts to analyse the immune response to this protein.

Amino Acid Sequence↗
PubMed1985

The sex difference in dichotic listening: multiple negative findings.

Verbal dichotic listening tests were administered to 477 normal, right-handed adults in five consecutive experiments. None of the five separate analyses yielded a significant sex difference in degree of ear asymmetry, nor was a significant difference found when data were pooled. Supplemental analyses provided some evidence of a sex difference among subjects without familial sinistrality. Nonetheless, subjects' sex accounts for a very small proportion of the total variance in ear asymmetry.

Adolescent↗
PubMed1985

Cloning studies on the gene coding for L-(+)-lactate dehydrogenase of Plasmodium falciparum.

We show that the L-(+)-lactate dehydrogenase (EC 1.1.1.27;L-lactate: NAD+-oxidoreductase) of Plasmodium falciparum (LDH-P) is encoded in the parasite genome. A monoclonal antibody (McAb 7.2) has been shown to bind the LDH-P subunit which has an apparent molecular mass of 35 kDa. A polyclonal antiserum raised against affinity purified LDH-P has been used to isolate cDNA clones containing LDH-P epitopes from a lambda gt11Tn5 expression library. DNA sequence analysis of one clone, lambda LDH-P.1, reveals a single open reading frame which shows a degree of homology to the N-terminal domain of known LDH amino acid sequences.

Amino Acid Sequence↗
PubMed1982

Asthma deaths.

Explore the source record for details and available documents.

Asthma↗
PubMed1982

Asthma deaths.

Explore the source record for details and available documents.

Asthma↗
PubMed1978

The organization of a human milk bank in a North Q ueensland hospital.

The development of a human milk bank with nursing mothers as donors of human milk is described. Breast milk is collected manually, and as aseptically as possible, by the mother in the privacy of her home, and the milk is transported frozen to the milk bank by a member of the Nursing Mothers' Association of Australia. A sample of expressed milk is also collected and sent to the Microbiology Department of the Australian Government Health Laboratory for bacteriological examination. The milk bank is suitably located in the paediatric ward of the Townsville General Hospital. Human milk which has been classed as bacteriologically safe is given untreated to hospitalized infants in preference to formula milk. The result is a human milk bank which is administered under medical and microbiological control.

Australia↗
PubMed1975

Childhood chemotherapy and later drug abuse and growth curve: a follow-up study of 30 adolescents.

The authors studies the correlation of methylphenidate medication in childhood with later drug abuse and growth in height. Thirty adolescents with histories of minimal brain dysfunction who had been treated for at least six months with chemotherapy were compared with 30 adolescents who had not been so treated. The findings do not indicate that methylphenidate prescribed in childhood contributed to later drug abuse or seriously interfered with growth in height.

Adolescent↗