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Biomedical subjects

M M Zitouna

Publications and source records attributed to M M Zitouna.

At least 19 recordsLinked to original sources

[Pyoderma gangrenosum. 15 cases].

We report a retrospective study of 15 cases of pyoderma gangrenosum. The male/female ratio was 2, average age 40 years (range: 2-48 years). The typical ulcerous form was observed in 11 patients, whereas bullous pyodrma gangrenosum was noted in 2 patients and the granulomatous superficial form in 2 others. The leg was the most frequent localization. It was often associated with another skin localization. Two patients had neutrophilic pulmonary involvement which was concomitant to the skin ulcers. Association with internal disease was found in 8 patients. Histology showed vasculitis in 11 patients. In 9 of them, leukocytoclastic vasculitis was observed. Prednisone and clofazimine were the most frequently prescribed drugs. Th rate of recurrence of pyoderma gangrenosum was 46% independently of treatment. Occurrence of neutrophilic pneumopathy was rapidly fatal in two of our patients

Adolescent↗

[Basal cell carcinoma arising in a seborrheic keratosis: a case report].

Seborrheic keratosis are one of the most common benign epidermic tumors in clinical practice. Malignant transformation is exceptional and occurs by the involvement of human papilloma virus. We report a case of seborrheic keratosis of the armpit in a 55 year-old woman whose biopsy revealed the presence of a basal cell carcinoma.

Basal Cell Carcinoma↗

[Paraganglioma of the cauda equina. Apropos of a case with review of the literature].

Paragangliomas are unusual neuroendocrine tumors. The most common anatomical site is within head and neck (90%). It has rarely been described in the region of the cauda equina. We report the case of a 49 years-old white woman who presented with a slow, progressive cauda equina syndrome over a 20-years period. Radiological examination showed erosion of the vertebral laminae of L4, L5 and S1 and disclosed an intra-dural mass lesion occupying the entire spinal canal between L4 and S1. The patient underwent sub-total excision and adjuvant radiation therapy. Histological examination concluded to a paraganglioma. This diagnosis was confirmed by immunohistochemical studies.

Cauda Equina↗

[Synovial lipoma arborescens].

The synovial lipoma are uncommon articular tumors of unknown origin. We report two cases of synovial lipoma arborescens arisen in a man and a woman respectively 41 and 27 years old. Both had already consulted for a tumefaction progressively increasing in volume. It was accompanied in the first case by a laxity in the knee joint. Radiography and arthroscopy showed an important hyperplasia of the articular synovia. A total synovectomy was performed in both cases. The synovia had a hairy aspect and was extremely thickened. It weighted 1.5 kg in the first case and its section had a fatty aspect. The histological examination confirmed the diagnosis of synovial lipoma arborescens. The observed aspect of the two tumors and particularly their volume, which was very important in the first case are arguments in favor of their tumoral nature.

Adult↗

[Fibrous inflammatory polyp of the digestive tract. Apropos of 5 cases].

Inflammatory fibroid polyp is a rare benign tumor of the digestive tract. The authors report three cases: two intestinal and one gastric. These cases are of particular interest because of the association ill one case of an intestinal submucosal lipoma with the inflammatory fibroid polyp, and the existence in the gastric case of an inflammatory reaction caused by food debris. This offers, further evidence in support of the theory implicating a chronic inflammatory reaction.

Aged↗

[Collagenous enterocolitis. Apropos of a case and review of the literature].

Collagenous enterocolitis is a recent entity of which only two cases have been published. The authors report the association of collagenous colitis and collagenous sprue in a 67-year-old woman. The diagnosis of collagenous enterocolitis is based on the presence of a duodenal collagen deposit with partial villous atrophy associated with collagenous colitis. The symptom appeared one month after non-steroidal antiinflammatory treatment. The authors discuss the role of drug toxicity in the pathogenesis of collagenous enterocolitis.

Aged↗

[Colloid cyst of the fourth ventricle. Apropos of a case].

We report a case of a 29 year old patient with a colloid cyst of the fourth ventricule. Colloid cysts or epithelial cysts are exceptional in this site. A common neuroepithelial origin with third ventricule cysts could be explained by similar embryological developments of the prosencephalic and the rhombencephalic roofs. The diagnosis can only be made by histological examination.

Adult↗

[Large placental chorioangiomas: 2 case reports].

Two cases of large placental chorioangiomas are reported. These tumors gave rise to obstetric and neonatal complications with perinatal death in both cases. These rare tumors were discovered by pathological examination of the products of delivery, with their precise nature being identified histologically. Review of the literature shows that fetal, neonatal and obstetric consequences are multiple and can often be explained by placental and cardiac insufficiency in utero secondary to the presence of these vascular tumors.

Adult↗

[Primary malignant melanoma of the rectum. A case report].

The authors report a case of primary malignant melanoma of the rectum seen in an 84-year-old woman. This blackish tumour measuring 3 cm in diameter and situated 8 cm from the anal margin was treated by surgical excision. The patient died during the immediate postoperative period.

Aged↗