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Biomedical subjects

M M Zion

Publications and source records attributed to M M Zion.

36 records · Page 2Linked to original sources

An unusual case of double-outlet left ventricle.

The first case of a double-outlet anterior left ventricle with normal relationships of the great vessels is reported (S.L.D.). This case is associated with a chromosomal trisomy--the exact nature of which is not yet clear. The clinical, electrocardiographic, echocardiographic and angiographic features are described.

Cardiac Catheterization↗

Complete atrioventricular canal with survival to the eighth decade.

Survival to the eighth decade of patients with atrioventricular canal is extremely rare. A patient is presented with such survival of the complete form of the defect. This possibly represents the first such report in the medical literature. The value of 2-dimensional echocardiography, particularly with venous contrast studies, in establishing the diagnosis, is shown.

Age Factors↗

Auscultatory features of hypertrophic obstructive cardiomyopathy. A study of 90 patients.

The auscultatory signs in 90 subjects with hypertrophic obstructive cardiomyopathy are described. The late-onset ejection systolic murmur and its responses to vaso-active manoeuvres reflect a volume-dependent outflow tract obstruction. Late vibrations of the systolic murmur, not uncommonly recorded at the apex, are due to associated mitral incompetence. Non-ejection systolic clicks may occur, and the likely explanation is inequality of the functional length of the mitral chordae tendineae secondary to asymmetrical myocardial hypertrophy. The second heart sound is often abnormal, usually with delay in the aortic component. Some correlation was demonstrated between the relative degrees of left and right ventricular outflow obstruction and the pattern of splitting of the second heart sound. Reversed or partially reversed splitting is usually associated with a more severe left ventricular outflow obstruction. Ejection systolic clicks and early diastolic murmurs occur infrequently, but are not incompatible with the diagnosis of hypertrophic obstructive cardiomyopathy.

Adolescent↗

Anomalous origin of the left coronary artery from the pulmonary artery: new electrocardiographic, echocardiographic and surgical observations.

The case of a two year old girl with anomalous origin of the left coronary artery from the pulmonary artery is described. She was never in heart failure but had cardiomegaly and anginal pain. The ECG showed a typical infarct pattern with left ventricular hypertrophy. An unusual finding was a prolonged QTc of 0.52. During cardiac catheterization and twice 24 hours later she developed ventricular fibrillation treated with electroshock and prevented later with propranolol. The QTc returned to normal after surgery. Echocardiography showed diastolic flutter and early systolic closure of the pulmonary valve. This disappeared after surgical correction. Transverse 2D echo of the aortic root showed a large right coronary artery which decreased in size after surgery. The left coronary artery was not seen on echocardiography. At cardiac catheterization the diagnosis of an anomalous origin of the left coronary artery from the pulmonary artery was established, with a large shunt to the pulmonary artery through the anomalous artery. Mild pulmonary hypertension and mild mitral regurgitation were present. At surgery, since direct implantation was technically impossible, the left coronary artery was successfully connected to the aorta via a 6 mm expanded Poly-Tetra-Fluoro-Ethylene (P.T.F.E.) graft.

Child, Preschool↗