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Biomedical subjects

M M Wood

Publications and source records attributed to M M Wood.

36 records · Page 2Linked to original sources

Evaluation of the Schirmer tear test.

We used the Schirmer filter paper test to measure tear production in 10 healthy women after instillation of local anesthetic drops at the same time of day for 30 or 31 consecutive days. We found that it was not a reliable indicator of tear production. The results varied widely even on the same subjects many of whom would, according to the standards for interpretation of the test, have been judged to produce an inadequate amount of tears.

Adult↗

Comparison of techniques to determine continence zone.

The urethral pressure profiles for 36 patients were analyzed specifically for continence zone by 3 techniques: 1) triangle, 2) planimeter and 3) weight. Graphically, the best agreement was between the weight and planimetry methods but, statistically, there was a significant difference among techniques except for the subgroup that had the smallest continence area.

Bladder Exstrophy↗

Efficacy and effectiveness issues in the NIDA Cooperative Agreement: interventions for out-of-treatment drug users. National Institute on Drug Abuse.

This paper examines the Cooperative Agreement (CA) HIV intervention studies for active drug users, sponsored by the National Institute on Drug Abuse, in terms of the constructs of prevention efficacy and effectiveness. A rationale is presented for conservatively interpreting outcome findings of these studies as indicative of intervention efficacy, as opposed to effectiveness. It is argued that the CA studies fall more within the domain of efficacy owing to the high degree of control and optimization that occurred with respect to intervention recruitment, participation, process monitoring, and staff training. Because the interventions were implemented and evaluated in community-based, noninstitutional settings with many real-world constraints, it is suggested that minimal shrinkage of their effects would occur if they were implemented in uncontrolled community settings. The relationship of intervention structure, content, process, dose, and participant characteristics to intervention efficacy is reviewed and discussed, both in general terms and with reference to the CA studies.

Acquired Immunodeficiency Syndrome↗