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Biomedical subjects

M M Walsh

Publications and source records attributed to M M Walsh.

At least 19 recordsLinked to original sources

Smokeless tobacco use: how it affects the performance of major league baseball players.

The authors examined the effect of smokeless tobacco use on the athletic performance of major league baseball players during the 1988 season. They evaluated performance records of 158 players on seven major league teams who played or pitched at least 10 games or innings during the 1988 season. ST use, they concluded, is not related to player performance in major league baseball but does place players at significantly increased risk for mucosal lesions and other oral pathology.

Adult

Characterization of the polymerase activity associated with cultured peripheral blood mononuclear cells from patients with Kawasaki disease.

The particulate fractions of culture supernatants from peripheral blood mononuclear cells from 39 patients with Kawasaki disease (KD) were examined for the presence of particle-associated reverse transcriptase activity. The peak polymerase activity was significantly higher in cultures from KD patients compared to controls (mean = 6.4 versus 3.6 pmol of dTMP incorporated, p = 0.001). PBMC cultured between the 3rd and 9th wk after onset of fever were most likely to be associated with reverse transcriptase activity. Peak polymerase activity was positively associated with older age (r = 0.41, p = 0.01) and greater magnitude of the serum IgA response at 7-14 d after onset of fever (r = 0.45, p = 0.01) and IgM response at 6-9 wk after onset of fever (r = 0.46, p = 0.01). The appearance of enzyme activity was not associated with a decrease in viability of the cultured cells. A purified enzyme preparation showed radiolabel incorporation only with an RNA template with DNA primer. These data suggest that circulating mononuclear cells from KD patients may harbor a polymerase-associated agent and that these cells can be most readily detected in the early convalescent phase of KD from older patients who mount a marked humoral immune response.

Age Factors

Trends in dental hygiene applicant pool size and characteristics of students upon entry over three decades.

A survey was conducted to determine trends that have occurred in the dental hygiene applicant pool and characteristics of entering dental hygiene students between 1957 and 1987. A two page, 46-item questionnaire with a cover letter and stamped pre-addressed envelope was mailed to each dental hygiene program director in the United States. A second mailing was sent one month later to directors who had not responded to the first mailing. A total of 106 usable questionnaires were returned, for a 54 percent response rate for 1987 programs. Response rates for programs existing in 1977, 1967, and 1957 were 51 percent, 45 percent, and 45 percent, respectively. For associate degree/certificate and baccalaureate degree programs, results suggest trends toward (1) a dramatic decline in dental hygiene applicants over the past ten years, (2) a decrease in dental hygiene class size, (3) an increase in age of applicants and length of education prior to acceptance into dental hygiene programs, and (4) a slight decrease in applicants' overall grade point average and science grade point average in the past decade. In addition, findings indicate that dental hygiene remains predominantly a Caucasian woman's profession. Implications of these findings for recruitment efforts and the numbers of dental hygienists for the future are discussed.

Adolescent

The economic contribution of dental hygienists' activities to dental practice: review of the literature.

This article reviews studies of dental practice and essays on practice management that have included information on the economic contributions of oral hygiene services. Several studies found that these services were less remunerative than other services and recommended that dentists delegate these functions when possible. However, one study noted that performance time, as well as delegation, influenced practice productivity and also reflected the practice's concept of care. Some practice management authors indicated that poorly managed practices without an excess of patients do not benefit economically from hiring a hygienist; but for practices with good management capabilities and an excess of patients, a hygienist may be able to make a major contribution to practice productivity. The lower remuneration for hygiene services and the high percentage of practice time required to provide a complete prophylaxis once or twice a year to each patient led several authors to doubt that dentists would or could provide these services themselves. The data in the reported studies, however, are insufficient to support firm conclusions about the profitability of hygienists' activities in dental practice.

Dental Hygienists

Clinical and microbiologic effects of single-dose metronidazole or scaling and root planing in treatment of adult periodontitis.

Sites affected with adult periodontitis were observed for 3 months to compare their clinical and microbiologic responses to a single 2 g dose of metronidazole, scaling and root planing, or no treatment. 2 sites with probing depths greater than or equal to 5 mm in each of 18 female subjects (6 in each treatment group) were evaluated clinically (plaque and bleeding indices, probing depth, attachment loss) and microbiologically (%s of cocci, motile rods, non-motile rods and spirochetes, and of obligate anaerobic colony-forming units, black-pigmented Bacteroides, Fusobacterium and Actinobacillus actinomycetemcomitans in subgingival plaque). No significant differences in these variables existed between the 3 groups at baseline. The no-treatment (control) group showed no substantial clinical or microbiologic changes during the study. After 1 month, scaling and root planing had effected significant clinical improvement and significant shifts in the subgingival flora to a pattern more consistent with periodontal health; these changes were still evident at 3 months. In contrast, 1 month after metronidazole, there was some clinical improvement and a significant increase in cocci and a decrease in motile rods, but at 3 months these changes were no longer evident. The results show that the benefits of scaling and root planing are sustained for at least 3 months. However, the benefits of a single 2 g dose of metronidazole are both few and transient, indicating that this regimen, while effective against anaerobic infections in other organ systems, is not clinically or microbiologically effective in the treatment of adult periodontitis.

Adult

Use of gingival bleeding for reinforcement of oral home care behavior.

The present study examined the use of gingival bleeding as a reinforcement mechanism for interproximal home care with the toothpick. After initial assessments of plaque and gingival bleeding, 36 subjects were given a professional toothcleaning and instructed to maintain oral hygiene by toothbrushing alone for 3 months. After 3 months of brushing only, subjects were re-examined and given another professional toothcleaning. Having been matched for age and percentage of sites bleeding on probing, as determined at the initial examination, they were than randomly attached to one of three groups. One group, the control, continued to clean their teeth with only a toothbrush, while the other two groups used the toothbrush supplemented with the toothpick for interproximal subgingival cleaning. Both toothpick groups received identical instruction in toothpick technique, but one group was taught to use bleeding as an interpretive device for health. Three months later, clinical assessments indicated significantly less gingival bleeding for both toothpick groups as compared with the control (whose gingival health worsened). Although there was no significant difference between the final scores of the toothpick groups, only the group that used gingival bleeding as a sign of disease showed a significant improvement in gingival health (P less than 0.003), and also had a fivefold higher rate of return of self-report compliance cards. These results suggest that the use of gingival bleeding as a reinforcement mechanism should be considered as a strategy in oral home care instruction to promote compliance with recommended behavior.

Adult

Effects of school-based dental health education on knowledge, attitudes and behavior of adolescents in San Francisco.

A field experiment was done to evaluate the short term effects of a series of classroom preventive dentistry presentations on dental health knowledge, attitudes and reported behavior of adolescents. Eight hundred fifty-four boys and girls, 12-14-yr-old students enrolled in San Francisco middle schools, were randomly divided into experimental and control groups. A written test composed of questions relating to factual dental health knowledge, home care practices, and attitudes to dental health was answered by the experimental group at the beginning and end of the educational intervention and at comparable time intervals by the controls. Results showed a significant increase in knowledge for the experimental group (P less than 0.001), as compared with the control group. Pre-existing attitudes were generally positive for most subjects. Although the educational intervention resulted in no significant differences between the two groups with regard to attitude, there was a significant positive change in attitude within the experimental group (P less than 0.01) from pre- to posttest. In addition, there was a significant increase in the frequency with which the girls in the experimental group reportedly used the toothbrush (P = 0.01) and dental floss (P = 0.01).

Adolescent