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Biomedical subjects

M M Shangold

Publications and source records attributed to M M Shangold.

28 records · Page 2Linked to original sources
PubMed1982

Menstrual irregularity in athletes: basic principles, evaluation, and treatment.

Recent advances in reproductive physiology have led to an understanding that the ovarian follicle controls the entire menstrual cycle. The most mature follicle, which is the best estrogen-producer, is most sensitive to gonadotropin stimulation and is destined to ovulate next. During the course of a training program, an athlete may be subjected to many factors including loss of weight and fat, low weight and fat, acute and chronic hormonal changes, and physical and emotional stresses. Each of these, alone or in combination, may be associated with menstrual irregularity or amenorrhea. Although menstrual irregularity and amenorrhea are common among athletes, these problems should always be evaluated thoroughly. It is dangerous to assume that such problems are either exercise-related or not serious. Athletes are not immune from developing significant pathology, which can be detected only if sought. Therapy is indicated for some women who have such menstrual dysfunction.

Anovulation↗
PubMed1977

Pregnancy following the "insensitive ovary syndrome".

A patient in whom the "insensitive ovary syndrome" was followed by a successful pregnancy is reported and discussed. Conception occurred while this patient was receiving estrogen therapy. The marked differences in her ovarian responsivity to endogenous and exogenous gonadotropin stimulation remain enigmatic.

Adult↗
PubMed1976

Plasma prostaglandin F 2-alpha levels in dysmenorrehic women.

Plasma prostaglandin F 2-alpha (PGF 2-alpha) concentrations were compared in nine ovulatory dysmenorrheic women, one dysmenorrheic oral contraceptive user, and two nondysmenorrheic control subjects, in an effort to demonstrate a relationship between plasma PGF 2-alpha levels and dysmenorrhea. In addition, the effects of aspirin, a known inhibitorof prostaglandins synthesis, on dysmenorrhea and on PGF 2-alpha levels were investigated. No statistical difference was demonstrated between the plasma PGF 2-alpha levels of dysmenorrheic and nondysmenorrheic subjects throughout the menstrual cycle. Attainment of an adequate salicylate level was accompanied by a significant decrease in PGF 2-alpha levels. All dysmenorrheic subjects reported improvement in symptoms while taking aspirin. The greatest subjective relief was reported by women who began taking aspirin (10 grains every 4 hours) 3 or more days prior to the onset of bleeding.

Adult↗
PubMedDate not supplied

Prevention of vaginal trichomoniasis by compliant use of the female condom.

BACKGROUND: Several case-control studies suggest that the male condom protects women against some sexually transmitted diseases. The female condom is the first barrier device under the woman's control that may be effective in the prevention of sexually transmitted diseases. GOAL OF THIS STUDY: To determine if appropriate use of the female condom decreased the rate of recurrent vaginal trichomoniasis in previously diagnosed and treated women. STUDY DESIGN: One hundred and four sexually active women with vaginal trichomoniasis were treated with metronidazole and assigned to a group using the female condom or a control group during a 45-day period of continued sexual activity. Fifty women served as controls, and 54 women were assigned to use the female condom. RESULTS: Only 20 women used the female condom each time they had sexual intercourse. Reinfection with trichomonas occurred in 7/50 (14%) controls, in 5/34 (14.7%) noncompliant users, and in 0/20 compliant users of the female condom. CONCLUSION: The compliant use of the female condom is effective in preventing recurrent vaginal trichomoniasis.

Adult↗