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Biomedical subjects

M M Schreiber

Publications and source records attributed to M M Schreiber.

At least 19 recordsLinked to original sources

The risk of developing subsequent nonmelanoma skin cancers.

Data from the Southeast Arizona Skin Cancer Registry collected during 1985 through June 1988 were used in this study. Patients who had a nonmelanoma skin cancer (basal cell or squamous cell carcinoma) removed in 1985 were observed until subsequent nonmelanoma skin cancers developed or until June 30, 1988. Twelve categories of nonmelanoma skin cancers were developed on the basis of the type of first nonmelanoma skin cancer and type of second, third, and fourth nonmelanoma skin cancers. Analyses showed the highest risk of a subsequent nonmelanoma skin cancer developing was within 1 year (36.39%), the rate of developing another nonmelanoma skin cancer depended on type (squamous cell carcinoma, 100%; basal cell carcinoma, 44.23% to 83.65%), and total risk decreased during the 1277 days of the study.

Aged↗

Chronic solar ultraviolet damage associated with malignant melanoma of the skin.

A retrospective study of 226 cases of cutaneous malignant melanoma (CMM) was done to determine if patients with CMM showed evidence of chronic solar ultraviolet radiation damage, i.e., a past history of actinic keratosis (AK), basal cell carcinoma (BCC), squamous cell carcinoma (SCC) anywhere on the patient's skin, and solar elastosis (SE) at the site of a CMM. This statistical analysis consisted of 119 clinical records and 158 pathology slides after all cases of lentigo CMM were deleted. CMM showed no statistical correlation with AK, BCC, SCC, or SE. This supports the idea that it is not the chronic solar-ultraviolet radiation exposure that causes CMM.

Adult↗

Malignant melanoma in southern Arizona. Increasing incidence and sunlight as an etiologic factor.

This study demonstrated an increasing incidence of malignant melanoma during the past ten years and a very high incidence of this tumor in southern Arizona. During the ten-year period, 533 melanomas were removed from white patients. Of these, 52% were male and 48% were female. The number of melanomas increased yearly, from 20 in 1969 to 120 in 1978, a crude rate incidence of 6.49 to 28.57 (27.20 standardized) per 100,000, respectively. This reflects an average annual increase of 34% to 37% and a 340% increase for the period. The highest incidence of tumor was in the 50 to 59 year and 60 to 69 year age groups. The most common site of occurrence was the back, with twice as many tumors arising there in males. The legs were involved in 13% of patients, with an occurrence rate eight times higher in females. The extremely high incidence of melanomas in southern Arizona is probably due to meteorologic and geographic factors allowing large amounts of ultraviolet light to reach the earth's surface.

Adolescent↗

Nail bed carcinoma.

Chronic conditions of the nail bed are frequently seen. Rarely a carcinoma will be present, which can only be diagnosed by a high degree of awareness of its possibility and then by performing a biopsy.

Aged↗