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Biomedical subjects

M M Mower

Publications and source records attributed to M M Mower.

99 records · Page 6Linked to original sources
PubMedDate not supplied

Anomalous origin of the right coronary artery from the pulmonary artery.

A 35-year-old woman was seen because of a two-year history of exertional dyspnea. She had a high-pitched systolic and diastolic murmur and evidence of left ventricular hypertrophy. Increased hemoglobin oxygen saturation was noted as the level of the pulmonary trunk, and indocyanine green dye curves were characteristic of a left-to-right shunt. Aortic root angiography revealed that the right coronary artery arose from the pulmonary trunk and that blood flow was reversed. The incidence, clinical manifestations, and therapy of this rare syndrome are reviewed.

Adult↗
PubMedDate not supplied

Considerations in the development of the automatic implantable defibrillator.

A highly reliable ventricular fibrillation detector and a satisfactory electrode system for delivering defibrillating pulses to the heart play a central role in the development of an automatic implantable defibrillator suitable for clinical use. Among the four implanted electrode designs tested, the combination of an electrode placed in the superior vena cava with a conformal electrode on the apex of the heart provided satisfactory defibrillation thresholds with ease of implantation. A new sensing method is also described for which an electrogram derived from the defibrillating electrodes is used as input. A form of a density function is developed for a filtered version of the input, ventricular fibrillation being characterized by a density curve lacking a large peak occurring at a level corresponding to the baseline of the filtered signal. These ideas are being incorporated into the design of a prototype implantable defibrillator delivering pulses of 24 joules.

Animals↗