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Biomedical subjects

M M Lindell

Publications and source records attributed to M M Lindell.

At least 19 recordsLinked to original sources
PubMed1993

Lymphography for staging lymphomas: is it still a useful procedure?

OBJECTIVE: The purpose of this study was to determine the current value of lymphography in a series of previously untreated patients with Hodgkin's and non-Hodgkin's lymphoma seen at the M. D. Anderson Cancer Center over a 1-year period. MATERIALS AND METHODS: From September 1989 through August 1990, 313 previously untreated patients with lymphoma were seen at our institution. In 221 of these, lymphography and CT were performed for abdominal staging. These studies were reviewed to determine if the examinations were complementary, or if the results of one or the other changed the staging in a significant number of patients. Staging was based on clinical findings, as laparotomies are rarely performed at this time. RESULTS: Lymphograms were abnormal and CT scans were normal in two patients with Hodgkin's disease and in two with non-Hodgkin's lymphomas. Biopsy proof of nodal disease was not available for any of these, but the nodes did not change after therapy in three patients. The other patient was seropositive for HIV, and HIV disease itself can cause nodal abnormalities. In one patient with Hodgkin's disease and 12 with non-Hodgkin's lymphoma, lymphograms were normal and CT scans were abnormal, showing enlarged nodes and/or abnormal architecture. CT scans obtained after therapy showed regression of nodal and extranodal masses. CONCLUSION: It was concluded that lymphographic findings did not significantly contribute to staging in these patients. This departure from previous experience may be due to improved state-of-the-art CT. In addition, the use of a combination of chemotherapy and radiation therapy to treat the lymphomas has increased, diminishing the need for detection of subtle nodal changes.

Hodgkin Disease↗
PubMed1992

Current use of lymphography for staging lymphomas and genital tumors.

The current literature and the experience at The University of Texas M.D. Anderson Cancer Center were reviewed to determine the current status of the use of lymphography for staging of malignant disease. Lymphography continues to be used for staging and surveillance of the lymphomas and, to some extent, for staging of carcinoma of the cervix. Testicular tumors are now primarily staged and followed by CT and serum markers. Currently, other abdominal and pelvic tumors are not commonly evaluated with lymphography.

Female↗
PubMed1990

Fibrous lesions of bones.

A large variety of benign and malignant fibrous lesions occur in the skeleton. Many fibrous bone lesions have characteristic features on plain radiographs and are easy to diagnose; others may pose significant difficulty. Most often, an osteolytic defect is seen associated with a fibrous lesion in the affected bone, although a mixed and sclerotic fibrous bone lesion is not unusual. Many benign fibrous bone lesions are asymptomatic; others become clinically apparent because of associated pathologic fracture or deformity of the involved bone. Malignant fibrous lesions tend to be aggressive, with focal bone destruction and adjacent soft-tissue involvement. The authors describe many fibrous bone lesions with their salient clinical and radiographic features.

Bone Diseases↗
PubMed1989

The clavicle: normal and abnormal.

The clavicle is an unusual long bone with many unique embryologic features. It is often involved in congenital and acquired disorders. Traumatic, inflammatory, neoplastic, metabolic and many other miscellaneous lesions may also affect the bone. Because of its ligamentous attachments and the presence of articulations at both ends, the clavicle can also be involved in arthritic diseases. This article illustrates the radiographic manifestations of many of the disorders of the clavicle that are commonly encountered in clinical practice.

Bone Diseases↗
PubMed1987

Parosteal osteosarcoma: radiologic-pathologic correlation with emphasis on CT.

Parosteal osteosarcoma, a distinct entity in which the neoplasm arises on the bone surface, presents characteristic features. Thorough radiologic and histologic evaluation and early definitive surgery usually result in a favorable prognosis and make limb salvage feasible in many adult patients. Twenty-six patients with proven parosteal osteosarcoma were seen at The University of Texas M. D. Anderson Hospital and Tumor Institute at Houston. All were examined by conventional radiography, 16 by CT, and one by both CT and MR. CT is valuable for the evaluation of tumor invasion of the medullary canal, involvement of the cortex, and extension into the soft tissues, findings frequently not demonstrable by other noninvasive techniques. Additional information is obtained regarding the presence and location of satellite lesions and intralesional radiolucent areas and the relationship of the vascular bundle to the tumor mass. These findings are important for planning both percutaneous biopsy and surgery.

Adolescent↗
PubMed1985

Appearance of the intact lymphomatous stomach following radiotherapy and chemotherapy.

Gastric lymphoma can be treated effectively by a combination of chemotherapy and radiotherapy of the intact stomach; this often eliminates the need for gastrectomy. This article presents 21 patients with gastric lymphoma and compares the radiographic appearance of the intact stomach before and after treatment. There was a variable decrease in lymphomatous involvement of the stomach during the first several months after radiotherapy alone or in combination with chemotherapy. Gastric atrophy with diminished distensibility and constrictive changes was observed, but most remarkable was the appearance of linitis plastica.

Adult↗
PubMed1985

Computed tomography of osteosarcoma after intraarterial chemotherapy.

The response to intraarterial cis-diamminedichloroplatinum II (CDP) chemotherapy was evaluated by computed tomography (CT) in 33 patients with pathologically proved osteosarcoma of the long or flat bones. Twenty-one of the 33 patients had a CT scan before chemotherapy was started. In the other 12 patients, a CT scan was obtained after at least two courses of treatment, and additional studies were performed during the course of therapy. In those patients responding to treatment, the posttherapy scan revealed a remarkable decrease or complete disappearance of the associated soft-tissue mass and clear reestablishment of the fat planes between the muscle bundles that had been obscured. There was sharp definition of the peripheral margins of the calcified healing neoplasm, and the calcification in the healing tumor could be differentiated easily from that of the original bone neoplasm. The findings of CT were compared with those of conventional studies and pathologic results. CT was more accurate than conventional studies in detecting healing process and diagnosis of remission.

Adolescent↗
PubMed1982

Mediastinal metastases from prostatic carcinoma.

We reviewed the frequency of intrathoracic metastases of prostatic cancer at initial presentation in 1,435 patients seen from 1968 to 1978. Of these patients 75 (5.2 per cent) had intrathoracic metastases, including nodular metastases in 60 (4.2 per cent), mediastinal adenopathy in 9 (0.6 per cent), mediastinal adenopathy and pulmonary nodules in 3 (0.2 per cent), and lymphangitic pulmonary metastases in 3 (0.2 per cent). Mediastinal adenopathy in patients with metastatic carcinoma of the prostate has not been emphasized previously. Responses to therapy are described. In addition to the 9 patients with mediastinal adenopathy at presentation 7 had mediastinal metastases during the course of the disease.

Humans↗
PubMed1981

The extremity soft-tissue lesion: a comparative study of ultrasound, computed tomography, and xeroradiography.

Twenty-five extremity soft-tissue lesions were evaluated by ultrasound (US), computed tomography (CT), and xeroradiography (XR). The lesion was detected by CT in 20 of 25 cases. In five cases, a soft-tissue tumor was not identified by CT due to small lesion size, isodensity, or the inability to distinguish scar tissue from recurrent tumor. Of the three modalities, the vascular bundle was most reliably defined by CT. In 20 of 25 cases, the lesion was detected by XR, but the size was accurately determined in only 13 cases.

Adolescent↗
PubMed1981

Primary oat cell carcinoma of the larynx.

Oat cell carcinoma of the larynx is a rare and highly malignant tumor. Five cases are reported and the world literature is reviewed. Three of the five patients had distant metastases when they were first seen with hoarseness. The radiographic and histologic findings and treatment regimen for one patient are described, as well as correct recommendations for therapy of these tumors.

Adult↗
PubMed1980

Radiologic evaluation of small esophageal carcinoma.

Eleven patients with small esophageal carcinomas are described. Double-contrast esophagography is essential in the detection of small esophageal tumors. In spite of the "early" detection, we did not find an improvement in survival in these patients.

Aged↗