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Biomedical subjects

M M Lewis

Publications and source records attributed to M M Lewis.

At least 73 records · Page 4Linked to original sources
PubMed1990

Case report 588: Intracortical chondroma of the left femur.

A case of intracortical chondroma in the left femur in a 22-year-old man is presented. Proof was obtained by open biopsy. The issue of periosteal vs intracortical chondroma was discussed in depth, with emphasis on the radiographic appearances. The differential diagnosis of this benign intracortical lesion was also included. The histopathologic characteristics of this intracortical chondroma were described and a possible explanation for the unusual location of the cartilage lesion within the cortex was considered.

Adult↗
PubMed1990

CO2 laser cauterization of giant-cell tumor margins.

The CO2 laser was evaluated to determine its effectiveness for marginal cauterization of giant-cell tumors after resectional curettage. Average power densities of 11-53 W/cm2 for corresponding application times of 120 and 60 seconds were found to produce 30 degrees temperature rises in fresh human femoral heads. This temperature was adequate to achieve thermal necrosis of the tumor margins to a depth of 5 mm. CO2 laser resection was found to be accurate and reproducible. No damage to underlying hyaline cartilage and soft tissues was evident histologically at one and four weeks after experimental local laser cauterization of distal femoral condyles in rabbits.

Animals↗
PubMed1990

Periosteal chondroma. A report of ten cases and review of the literature.

Periosteal chondroma is a slow-growing benign cartilaginous tumor of limited size arising within or under the periosteum, which, through constant pressure, induces cortical erosion and periosteal reaction. Ten new cases of periosteal chondroma are reported. All were treated by marginal or intralesional excision. No local recurrence was seen following this treatment. These patients demonstrated the clinical, roentgenographic, and pathologic features of this benign entity, which aid diagnosis, thereby avoiding overtreatment.

Adult↗
PubMed1990

Case report 603. Giant cell reparative granuloma of the distal end of right femur.

A GCRG of the femur in a 57-year-old man was described. He had undergone local radiotherapy and systemic chemotherapy for T-cell lymphoma of the jaw and scalp diagnosed 4 weeks previously. Since radiologically the lesion suggested an aggressive process, malignant lymphoma was the most probable preoperative diagnosis. In the differential diagnosis giant cell tumor, brown tumor of hyperparathyroidism, benign fibrous histiocytoma, and malignant fibrous histiocytoma were discussed in further detail. This histologically documented case of GCRG of the femur without any underlying process appears to be the first case reported in a long bone. It is unclear if the reparative process was primary or represented a reaction of the host bone to lymphoma which had completely responded to chemotherapy.

Diagnosis, Differential↗
PubMed1989

Juxtacortical liposarcoma. A case report and review of the literature.

Juxtacortical liposarcoma is an uncommon entity. The purpose of this paper is to report the case of a 63-year-old man with juxtacortical liposarcoma. Liposarcomas arising as surface lesions of bone are extremely rare. Histologically, juxtacortical liposarcoma is composed of myxoid and round-cell areas. Because of the extent of compartmental involvement and the high-grade malignancy, limb-sparing surgery was not considered for the patient. A review of the English literature on diagnosis and treatment indicates a grave prognosis.

Femoral Neoplasms↗
PubMed1989

Osteosarcoma. Clinical and pathological considerations.

The current local recurrence rate following limb sparing surgery for osteosarcoma is on the order of 5 per cent. Major advances in both reconstructive surgery and adjuvant chemotherapy have dramatically improved the disease-free survival rate and the quality of life in patients with osteosarcoma.

Bone Neoplasms↗
PubMed1989

Soft-tissue tumors and tumor-like lesions of the foot. An analysis of eighty-three cases.

The cases of eighty-three patients who had a soft-tissue tumor or tumor-like lesion in the foot or ankle were retrospectively analyzed to determine the relative frequency of the lesions and which factors, if any, could be used to identify them preoperatively. Seventy-two (87 per cent) of the lesions were benign, with ganglion cysts and plantar fibromatoses being the most common, and eleven (13 per cent) were malignant tumors, five (45 per cent) of which were synovial sarcomas. The age of the patient and the location of the lesion were the two most important factors that characterized the malignant tumors. For eight patients (12 per cent), radiographs were helpful in identifying the nature of the lesion. The sex of the patient, a history of trauma, the duration of the symptoms, the size of the lesion, and the presence of pain or of neurological symptoms were not useful in discriminating a benign lesion from a malignant tumor.

Adolescent↗
PubMed1988

Giant cell tumor of the ischium. A report of two cases and review of the literature.

The ischium represents one of the rarest sites of giant cell tumor of bone. Two additional cases are presented here. The unusual site, aggressive appearance and occurrence in older individuals are suggestive of other primary and secondary malignancies. Characteristic features of giant cell tumor and current treatment options are reviewed.

Bone Neoplasms↗
PubMed1988

Treatment of enchondromas of the hand with allograft bone.

We investigated whether cortico-cancellous allograft obtained from cadaveric banked bone is effective in the treatment of enchondroma of the hand. Twelve patients had 15 operations on 19 enchondromas using allograft bone. These patients were compared with 16 patients with enchondroma treated with autogenous iliac cancellous bone. The distribution of tumors was similar in both groups. There was no significant difference in the patient's age, their occupations, or whether the operation involved the dominant hand. In both groups, immobilization was maintained until clinical union was obtained. The duration of immobilization for both groups was identical. There were no recurrences, refractures, or complications in patients treated with allograft bone. The grafts incorporated and remodeled in all patients. We concluded that a allograft cortico-cancellous bone can be used effectively in the treatment of enchondromas of the hand. It is especially useful in the treatment of patients with multiple tumors.

Adolescent↗
PubMed1988

An unusual case of cystic chondroblastoma of the calcaneus: a case report.

A rare case of chondroblastoma of the calcaneus with a significant cystic component is presented. The difference in cure rate and clinical behavior between this lesion and others that would be considered in the differential diagnosis makes awareness of its existence and an accurate histologic diagnosis essential.

Adult↗
PubMed1988

The potential role of the laser in marginal sterilization of giant cell tumor following curettage.

Giant cell tumor is considered to be a lesion which behaves locally in an aggressive fashion and has a high local recurrence rate. Several physical adjuvant methods have been employed to reduce the local recurrence rate including cryosurgery with liquid nitrogen, phenol instillation, and the use of methylmethacrylate. In laboratory conditions, the authors applied a CO2 laser beam to eliminate traces of residual tumor tissue. As a mode of physical adjuvant treatment, use of the laser seems to be a promising technique for local tumor control.

Bone Neoplasms↗