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Biomedical subjects

M M Henton

Publications and source records attributed to M M Henton.

32 records · Page 2Linked to original sources
PubMed1995

The distribution of Pasteurella haemolytica serotypes among cattle, sheep, and goats in South Africa and their association with diseases.

Over an 8-year period (September 1986 to March 1994), a total of 497 organ specimens from sheep and goats and 96 from cattle, were received for their isolation of Pasteurella haemolytica. They were collected in seven geographical areas in South Africa (as it existed before the April 1994 elections). These areas include the eastern Cape, Transvaal (new name: Gauteng), Nambia, Orange Free State (new name: Free State), Natal (new name: KwaZulu-Natal), western Cape and the northern Cape. This investigation does not represent the statistical incidence of the organism from each region, only the distribution of serotypes isolated from organ specimens submitted from diseased animals in these regions. Pasteurella haemolytica serotype 6 was the most prevalent type isolated from sheep and goats, but was followed closely by types 9 and 2. From cattle, P. haemolytica serotype 1 comprised 39% of the isolates. In sheep and goats, the majority of serotypes were associated with pneumonia, followed by gangrenous mastitis ("blue udder") and septicaemia. The situation in cattle was similar regarding the incidence of pneumonia followed by septicaemia. Up to 33% of the isolates from cattle and sheep specimens were non-typeable.

Animals↗
PubMed1995

Artificial transmission of Bolo disease in woolled sheep and attempted characterisation of the causative unclassified Corynebacterium sp.

Bacterial isolates (n = 38) previously cultured from sheep with Bolo disease were compared bacteriologically with known Corynebacterium spp. and Actinomyces spp. The isolates did not conform to any previously described species but closely resembled C. pseudodiptheriticum and C. urealyticum. More comprehensive tests are needed to classify this Corynebacterium sp. Bacterial cultures of this unclassified Corynebacterium sp. were used artificially to induce Bolo disease in Dohne Merino sheep (n = 20). Ten sheep were kept at Middelburg in the Cape Midlands (Northern Cape) under arid conditions and another 10 at Queenstown in the Eastern Cape in a more humid climate. Two suspensions containing 2.8 x 10(5) Corynebacterium sp. (inoculum A) and 2.8 x 10(9) Corynebacterium sp. (inoculum B) respectively were used to infect each sheep on 9 different sites on the skin. One sheep died during the course of the experiment. Corynebacterium sp. established itself on 81 out of 171 inoculation sites of the remaining sheep and caused typical lesions of Bolo disease, clinically and pathologically. Bolo disease lesions developed slowly over 175 days at Middelburg and 287 days at Queenstown. Weather conditions were unfavourable to the development of fleece-rot and mycotic dermatitis. No difference was seen in lesion development between rams and ewes or between sheep with 5 months' wool growth and those which were shorn before inoculation. More lesions developed with the higher concentration of inoculum B (49 sites positive) as compared to inoculum A (32 sites positive).

Actinomyces↗
PubMed1994

A review of mycotic nasal granuloma in cattle, with a report on three cases.

Three cases of nasal mycotic granuloma containing fungal cells and hyphae in cattle are described. In 2 animals a mucopurulent or purulent nasal discharge was seen clinically, and epistaxis in the third. Histologically, ulceration of the nasal mucosa and a severe granulomatous inflammation of the nasal submucosa with eosinophils as the predominant cell type were evident in the cattle. Non-pigmented fungal cells identified as chlamydospores and short septate hyphae were demonstrated in giant cells and extracellularly within the granulomatous reactions. In one case, the fungal elements were frequently surrounded by homogeneous eosinophilic (Splendore-Hoeppli) material. Dematiaceous fungi, Bipolaris sp. and Drechslera sp., were isolated from 2 cases. Mycology was not performed on the third animal.

Animals↗
PubMed1993

The identification of Mycoplasma mycoides mycoides LC as the aetiological agent of balanoposthitis and vulvovaginitis in sheep in South Africa.

Clinical ulcerative balanoposthitis and vulvovaginitis was experimentally reproduced in 14 sheep infected with a Mycoplasma mycoides mycoides LC field strain, isolated from the Straussheim Dorper stud. The study encompassed a series of field observations, a therapeutic trial and experimental investigations. A wide range of bacteria and various mycoplasma spp., but no viruses, were isolated from a large number of infected animals.

Animals↗
PubMed1990

Systemic cryptococcosis in a cat.

A three-year-old, castrated, male, domestic cat presented with an antibiotic-resistant rhinitis, generalised lymphadenopathy, and skin nodules distributed over the neck, thorax and abdomen. Cryptococcus neoformans was identified on cytology and histopathology specimens, and cultured from all the specimens submitted. The cat died without antimicrobial therapy being instituted. Systemic cryptococcosis was confirmed on necropsy. Lesions were found in the upper and lower respiratory tracts, skin, subcutis, skeletal musculature, lymph nodes, kidney, eye and brain. This report details a case of systemic cryptococcosis in a cat and gives a review of feline cryptococcosis.

Animals↗
PubMed1984

Furunculosis in rainbow trout (Salmo gairdneri) raised in sea water.

Ulcerative skin lesions were encountered in rainbow trout raised in sea water by a commercial concern in the Western Cape, South Africa. Grossly, the lesions resembled furunculosis but, histopathologically, they differed from typical furunculosis in that bacterial colonies were rarely found in the organs, and also the kidneys and spleens were minimally involved. The causative organism was identified as an achromogenic Aeromonas salmonicida that shared characteristics with all 3 subspecies, salmonicida, masoucida and achromogenes. This is the first report of an outbreak of this disease in South Africa.

Aeromonas↗
PubMed1983

Cutaneous flavobacteriosis--polymorphous skin granulomas from Flavobacterium capsulatum. A case report.

A case of multiple eruptive skin granulomas caused by Flavobacterium capsulatum is described. The organism was resistant or poorly sensitive to all antibiotics except carbenicillin. Cure was brought about by using maximal doses of this drug. The source of the infection could not be proved, but it dated from an orthopaedic procedure to the elbow which was followed by a chronic cellulitis at the operation site. Since this is an organism known to occur in stored water, it was presumed that the flavobacterium was introduced into the wound from bottles of boiled and cooled water used in the operating theatre.

Bacterial Infections↗
PubMed1975

Chlamydiosis in a beef herd.

Chlamydial infection in a large beef herd is illustrated and discussed. The pre-natal and post-natal losses that occurred during 1972 are highlighted. Total pre-natal losses for the nine calving herds comprising 2,915 animals varied between 3,7% and 12,4%. Between 1,2% and 11,4% of the calves born alive in the nine herds died before weaning with 70% of the losses occurring within the first three weeks of life. Chlamydial organisms were demonstrated in pre-natal and post-natal losses from all nine herds. Clinical manifestations and lesions involving the intestinal, respiratory, nervous, skeletal, reticulo-endothelial and urinary systems were observed in chlamydia-infected calves. Invariably at autopsy in chlamydia positive cases there was some degree of a fibrinous inflammatory process present. Serological evidence showed that chlamydial organisms had been present on both farms prior to the 1972 investigations.

Abortion, Veterinary↗